Showing 19,921 - 19,940 results of 21,342 for search '(( significant decrease decrease ) OR ( significantly altered decrease ))', query time: 0.51s Refine Results
  1. 19921

    Table 3_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx by Wenqiao Jia (12356306)

    Published 2025
    “…</p>Conclusion<p>Our findings elucidate the molecular mechanism that PCP4 downregulation promotes PCa progression via Ca<sup>2+</sup>/CAMKK2/AMPK/AR pathway, highlighting its significance in CRPC development.</p>…”
  2. 19922

    Table 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.xlsx by Shenglan He (7641308)

    Published 2025
    “…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …”
  3. 19923

    Supplementary file 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf by Wei Gong (112494)

    Published 2025
    “…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …”
  4. 19924

    Image 1_Immunomodulatory effects of probiotic Lactobacillus brevis ZG2488 on SARS-CoV-2 vaccine responses in mice.tif by Mengshan Chen (14303892)

    Published 2025
    “…</p>Results<p>ZG2488 intervention significantly enhanced local mucosal humoral immunity in the respiratory tract (increased SARS-CoV-2-specific IgG in BALF) and systemic Th1 cellular immunity (increased IFN-γ secretion by splenocytes). …”
  5. 19925

    S1 File - by Shi-jie Wang (18569781)

    Published 2025
    “…The results showed that muscle TOR knockdown and endurance exercise significantly increased the climbing speed, climbing endurance, the expression of autophagy related gene 2(ATG2), silent information regulator 2(SIR2), and pparγ coactivator 1(PGC-1α) genes, and superoxide dismutases(SOD) activity, but it decreased the expression of the TOR gene and reactive oxygen species(ROS) level, and it protected the myofibrillar fibers and mitochondria of skeletal muscle in Drosophila on a high-salt diet. …”
  6. 19926

    Image 1_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... by Ting Yang (189879)

    Published 2025
    “…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …”
  7. 19927

    YOLOv8n structure diagram. by Yaojun Zhang (389482)

    Published 2025
    “…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”
  8. 19928

    Supplementary file 1_The gut commensal Faecalibacterium hominis attenuates indole—AhR signaling and restores ASD—like behaviors with BTBR mice.docx by You Yu (2102071)

    Published 2025
    “…Oral administration of 4P-15 significantly reduced the intestinal levels of indole, indole-3-propionic acid (IPA), and indole-3-acetic acid (IAA), as well as the level of IPA in brain. …”
  9. 19929

    DataSheet9_Refining dual RNA-seq mapping: sequential and combined approaches in host-parasitic plant dynamics.csv by Carmine Fruggiero (20143830)

    Published 2024
    “…The evolutionary distance between parasitic and host plants did not significantly impact the accuracy of read assignment to their respective genomes since enough polymorphisms were present to ensure reliable differentiation. …”
  10. 19930

    Image 4_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... by Ting Yang (189879)

    Published 2025
    “…Furthermore, 29 out of 47 differential metabolites significantly correlated with the eight dominant microbial genera. …”
  11. 19931

    DataSheet_1_RETRACTED: Macrophages depletion alleviates lung injury by modulating AKT3/GXP4 following ventilator associated pneumonia.docx by Youfeng Zhu (2460811)

    Published 2024
    “…Depletion of macrophages protected against lung epithelial cells and significantly decreased MMP9, MMP19, FTH, and FTL expression levels and increased GPX4 expression levels, while partially reversing the changes in macrophage. …”
  12. 19932

    Table_4_Taxifolin increased semen quality of Duroc boars by improving gut microbes and blood metabolites.DOCX by Yexun Zhou (11711813)

    Published 2025
    “…We discovered that TAX increased sperm motility significantly in Duroc boars by the elevation of the protein levels such as ZAG, PKA, CatSper, and p-ERK for sperm quality. …”
  13. 19933

    Image 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

    Published 2025
    “…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”
  14. 19934

    Dust deposition, escape data table. by Yuxuan Liu (349237)

    Published 2025
    “…Results indicate that installing a return pipe significantly reduces dust overflow caused by impact airflow during blanking. …”
  15. 19935

    raw data for GCB paper.xlsx by Dongming Wang (21443882)

    Published 2025
    “…</p><p dir="ltr">Decades of Free Air CO<sub>2</sub> Enrichment (FACE) experiments show that projected atmospheric carbon dioxide (CO<sub>2</sub>) increases significantly influence crop systems, impacting food security. …”
  16. 19936

    Table 1_Socioeconomic status and motor coordination function among children with autism.docx by Muqing Cao (8308815)

    Published 2025
    “…Mothers without a college degree showed a decreased likelihood of probable DCD (OR: 0.33, 95%CI: 0.15-0.71).…”
  17. 19937

    Data Sheet 11_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

    Published 2025
    “…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
  18. 19938

    Geometric model of the binocular system. by Yaojun Zhang (389482)

    Published 2025
    “…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”
  19. 19939

    Enhanced dataset sample images. by Yaojun Zhang (389482)

    Published 2025
    “…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”
  20. 19940

    Data Sheet 1_BMP9 induces postnatal zonal stratification of immature articular cartilage through reconfiguration of the existing collagen framework.pdf by Miles Anderson-Watters (20626604)

    Published 2025
    “…In explants exposed to BMP9, collagen fibrils underwent angular displacement from 19° to 78° with respect to the surface, cell density decreased 1.77-fold, and chondrons were significantly larger. …”