Search alternatives:
significantly altered » significantly affected (Expand Search), significantly elevated (Expand Search), significantly lower (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
altered decrease » altered release (Expand Search), observed decrease (Expand Search), teer decrease (Expand Search)
significantly altered » significantly affected (Expand Search), significantly elevated (Expand Search), significantly lower (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
altered decrease » altered release (Expand Search), observed decrease (Expand Search), teer decrease (Expand Search)
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Autapses play a crucial role in PV interneuron’s sustained firing at high frequencies.
Published 2025“…Average action potential (AP) frequency in response to 0−650 pA current steps illustrating a significant increase in PV interneuron firing frequency at low-current steps in control cells without autapses (gray) compared to control cells with autapses (black). …”
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All data points from Fig 2.
Published 2025“…Using whole-cell patch-clamp recordings to examine intrinsic properties of PV interneurons in the PFC, we found that juvenile demyelination in mice induced robust alterations of PV interneuron firing patterns. Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”
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All data points from Fig 5.
Published 2025“…Using whole-cell patch-clamp recordings to examine intrinsic properties of PV interneurons in the PFC, we found that juvenile demyelination in mice induced robust alterations of PV interneuron firing patterns. Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”
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All data points from Fig 8.
Published 2025“…Using whole-cell patch-clamp recordings to examine intrinsic properties of PV interneurons in the PFC, we found that juvenile demyelination in mice induced robust alterations of PV interneuron firing patterns. Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”
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All data points from Fig 3.
Published 2025“…Using whole-cell patch-clamp recordings to examine intrinsic properties of PV interneurons in the PFC, we found that juvenile demyelination in mice induced robust alterations of PV interneuron firing patterns. Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”
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All data points from Fig 1.
Published 2025“…Using whole-cell patch-clamp recordings to examine intrinsic properties of PV interneurons in the PFC, we found that juvenile demyelination in mice induced robust alterations of PV interneuron firing patterns. Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”
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All data points from Fig 4.
Published 2025“…Using whole-cell patch-clamp recordings to examine intrinsic properties of PV interneurons in the PFC, we found that juvenile demyelination in mice induced robust alterations of PV interneuron firing patterns. Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”
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All data points from Fig 9.
Published 2025“…Using whole-cell patch-clamp recordings to examine intrinsic properties of PV interneurons in the PFC, we found that juvenile demyelination in mice induced robust alterations of PV interneuron firing patterns. Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”
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All data points from Fig 7.
Published 2025“…Using whole-cell patch-clamp recordings to examine intrinsic properties of PV interneurons in the PFC, we found that juvenile demyelination in mice induced robust alterations of PV interneuron firing patterns. Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”
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All data points from Fig 6.
Published 2025“…Using whole-cell patch-clamp recordings to examine intrinsic properties of PV interneurons in the PFC, we found that juvenile demyelination in mice induced robust alterations of PV interneuron firing patterns. Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”