Image 3_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.png by Jianyan Pan (20681864)

“…Notably, a high PAscore was also associated with decreased sensitivity to immunotherapy. Within the HCC microenvironment, malignant cells exhibited polyamine metabolic heterogeneity, those with high polyamine metabolic activity showed altered hallmark pathway signatures and increased communication with myeloid cells. …”

Image 2_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.png by Jianyan Pan (20681864)

“…Notably, a high PAscore was also associated with decreased sensitivity to immunotherapy. Within the HCC microenvironment, malignant cells exhibited polyamine metabolic heterogeneity, those with high polyamine metabolic activity showed altered hallmark pathway signatures and increased communication with myeloid cells. …”

Image 1_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.tif by Jianyan Pan (20681864)

“…Notably, a high PAscore was also associated with decreased sensitivity to immunotherapy. Within the HCC microenvironment, malignant cells exhibited polyamine metabolic heterogeneity, those with high polyamine metabolic activity showed altered hallmark pathway signatures and increased communication with myeloid cells. …”

Data Sheet 3_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.csv by Jianyan Pan (20681864)

“…Notably, a high PAscore was also associated with decreased sensitivity to immunotherapy. Within the HCC microenvironment, malignant cells exhibited polyamine metabolic heterogeneity, those with high polyamine metabolic activity showed altered hallmark pathway signatures and increased communication with myeloid cells. …”

Data Sheet 4_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.csv by Jianyan Pan (20681864)

“…Notably, a high PAscore was also associated with decreased sensitivity to immunotherapy. Within the HCC microenvironment, malignant cells exhibited polyamine metabolic heterogeneity, those with high polyamine metabolic activity showed altered hallmark pathway signatures and increased communication with myeloid cells. …”

Data Sheet 1_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.csv by Jianyan Pan (20681864)

“…Notably, a high PAscore was also associated with decreased sensitivity to immunotherapy. Within the HCC microenvironment, malignant cells exhibited polyamine metabolic heterogeneity, those with high polyamine metabolic activity showed altered hallmark pathway signatures and increased communication with myeloid cells. …”

Impact of Gemin5 in protein synthesis: phosphoresidues of the dimerization domain regulate ribosome binding by Salvador Abellan (19499424)

“…Moreover, cap-dependent protein synthesis was significantly altered by the triple substitution STS/DDD, pointing towards a role of these residues in protein synthesis regulation.…”

Supplementary file 1_Effects of human urine application on soil physicochemical properties, microbial communities, and enzymatic activities.docx by Guangquan Yu (21630101)

“…<p>Human urine (HU) is rich in nutrients necessary for plant growth, and recycling HU as fertilizer has multiple positive impacts, such as enhancing agricultural sustainability, reducing wastewater pollution, and decreasing reliance on chemical fertilizers, so it is of great significance to explore the effects of urine agricultural utilization on soil environment. …”

Core_models.R by Kryštof Korejs (18156751)

“…Total bird species richness was similar in P1 and S1 forests, but decreased significantly in P2 and S2 forest. Contrasting patterns in community metrics were observed for different bird feeding guilds. …”

Core_dataset.csv by Kryštof Korejs (18156751)

“…Total bird species richness was similar in P1 and S1 forests, but decreased significantly in P2 and S2 forest. Contrasting patterns in community metrics were observed for different bird feeding guilds. …”

Data Sheet 1_Lactobacillus paragasseri HM018 derived from breast milk ameliorates hyperlipidemia in high-cholesterol rats by modulating bile acid metabolism.docx by Chunyu Yao (13559263)

“…Metabolomic profiling further indicated that HM018 significantly altered bile acid composition by modulating gut microbiota-mediated bile acid metabolism. …”

DataSheet1_Transcriptomic and sugar metabolic analysis reveals molecular mechanisms of peach gummosis in response to Neofusicoccum parvum infection.zip by Yang Zhang (30734)

“…Our results revealed that N. parvum infection drastically altered the transcripts of cell wall degradation-related genes, the log₂Fold change in the transcript level of Prupe.1G088900 encoding xyloglucan endotransglycosylase decreased 2.6-fold, while Prupe.6G075100 encoding expansin increased by 2.58-fold at 12 hpi under N. parvum stress. …”

Data Sheet 1_Aloe-emodin plus TIENAM ameliorate cecal ligation and puncture-induced sepsis in mice by attenuating inflammation and modulating microbiota.docx by Jingqian Su (666622)

“…We also observed a significantly altered peritoneal cavity microbiota composition post-treatment, characterized by reduced pathogenic bacteria (Bacteroides) abundance. …”

Supplementary Material for: Impact of Ketogenic Diet on Weight, Metabolic, and Endocrine Parameters in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis by figshare admin karger (2628495)

“…Moreover, LH concentrations were significantly reduced (SMD 1.12 ng/dL [0.39, 1.84] p=0.003), FSH levels raised (SMD -0.76 ng/dL [-1.25, -0.28], p=0.002), the LH/FSH ratio decreased (SMD 2.04 (95% CI 1.04-3.03, p<0.001); testosterone decreased (free-T SMD 0.57 ng/dL [95% CI 0.28, 0.86], p<0.001; total-T SMD 0.54 ng/dL, 95% CI 0.28, 0.80, p<0.001), and SHBG levels were significantly increased (SMD 0.79, 95% CI [1.24-0.34],p<0.001). …”

Table 2_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Supplementary file 1_Multimodal MRI study of gray matter and functional connectivity abnormalities in adolescents with bipolar disorder.docx by Pengyu Zhu (1819939)

“…VBM analysis demonstrated decreased GMV in the left cerebellum. No significant correlations were found between imaging measures and clinical scale ratings.…”

Data Sheet 2_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Data Sheet 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Table 4_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Table 3_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”