Table 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx by Meng Yi (7853249)

“…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …”

Table 1_Association of cardiovascular health with reproductive lifespan and pregnancy loss: insights from NHANES 2005–2018.pdf by Yang Yan (222441)

“…Background<p>Altered reproductive timing of females has close relations to long-term health. …”

Table 2_Association of cardiovascular health with reproductive lifespan and pregnancy loss: insights from NHANES 2005–2018.docx by Yang Yan (222441)

“…Background<p>Altered reproductive timing of females has close relations to long-term health. …”

Multi-omics reveals glycolipid metabolism processes during the early development of largemouth bass (Micropterus salmoides) by Yujie Jiang (2991267)

“…Early embryos' yolk and oil droplet diameters decreased significantly with embryonic development (P < 0.05). …”

Supplementary file 1_Dachaihu decoction ameliorates abnormal behavior by regulating gut microbiota in rats with propionic acid-induced autism.docx by Yangyang Zhang (608493)

“…Meanwhile, the small clinical trial revealed that DCHD significantly alleviated the core symptoms of ASD, with decreased ADOS-2 and ABC scale scores. …”

Data Sheet 1_Dachaihu decoction ameliorates abnormal behavior by regulating gut microbiota in rats with propionic acid-induced autism.zip by Yangyang Zhang (608493)

“…Meanwhile, the small clinical trial revealed that DCHD significantly alleviated the core symptoms of ASD, with decreased ADOS-2 and ABC scale scores. …”

Figure 5 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma by Gwendolyn M. Cramer (16964052)

“…<p>PDT decreases PD-L1 expression and significantly reduces tumor growth after TI. …”

Data Sheet 1_Integrated transcriptomic analysis identifies lactylation-linked gemcitabine resistance and therapeutic targets in intrahepatic cholangiocarcinoma.docx by Wenwei Xie (1987225)

“…Immune landscape analysis indicated altered immune cell infiltration, including increased M2 macrophages and decreased CD8⁺ T cells in the high group. …”

Data Sheet 1_Distinct effects of global signal regression on brain activity during propofol and sevoflurane anesthesia.pdf by Fa Lu (478779)

“…Network topology analyses demonstrated that GSR minimally affected propofol-induced changes in graph theoretical measures but significantly diminished sevoflurane-related network alterations.…”

Data_Sheet_1_Responses of diazotrophic network structure and community diversity to alfalfa-maize intercropping are soil property-dependent.docx by Jinglei Zhang (311803)

“…However, in the average soil, it was the A/M system that had an altered diazotrophic structure, with an increased abundance of 11 bacterial genera and a decreased abundance of three bacterial genera (p < 0.05).…”

Table1_Around the clock: unveiling giraffe rest-activity rhythms and social dynamics.docx by Hanna Mebus (19961244)

“…The presence of a male giraffe during one intervention phase significantly altered diurnal activity patterns, increasing standing behaviors and decreasing feeding time. …”

Supplementary file 1_Effects of microbial organic fertilizers on soil microbial communities and physicochemical properties in tobacco cultivation.docx by Shengli Wang (4318522)

“…</p><p>Results and Discussion: The results indicated that MOF reduced the uptake of ammonium nitrogen by tobacco at different growth stages, promoted the dispersion of the microbial community, and significantly altered the soil microbial community structure. …”

Table 1_High-calcium milk improves osteoporosis in postmenopausal women by regulating intestinal flora and steroid hormone biosynthesis.docx by Yanyan Zhao (211551)

“…</p>Results<p>A one-year randomized controlled trial showed that the high-calcium milk group significantly increased lumbar spine bone mineral density (L1-4 BMD), slowed bone loss in the left hip and femoral neck, elevated serum phosphorus and 25-hydroxyvitamin D levels, and modulated the bone formation marker procollagen type I N-terminal propeptide compared with the regular milk group at 6 months. 16S ribosomal ribonucleic acid sequencing showed that high-calcium milk significantly altered the β-diversity of the intestinal flora, increasing the abundance of beneficial bacteria such as Bacteroides, Oscillibacter, and Subdoligranulum, while decreasing the abundance of Firmicutes and Weissella at 12 months. …”

Image 2_Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model.jpeg by Yang Li (7082)

“…Compared to the Nail group, AST serum concentrations were significantly decreased in the Nail+Therapy group after 72 h (p<0.05). …”

Image 1_Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model.jpeg by Yang Li (7082)

“…Compared to the Nail group, AST serum concentrations were significantly decreased in the Nail+Therapy group after 72 h (p<0.05). …”

Table_1_RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance.DOCX by Jianmin Chen (330051)

“…The hearts were subjected to LC-MS/MS based lipid mediator profiling. Many SPMs were significantly reduced in septic hearts, among which RvE1 had a ~93-fold reduction. …”

Data Sheet 1_Brain injury, endocrine disruption, and immune dysregulation in HIV-positive men who have sex with men with late HIV diagnosis.docx by Yihui He (2936874)

“…Participants in the LD group exhibited differences in brain function with certain regions and decreased functional connectivity between these altered regions and connected structures. …”

Data Sheet 1_Impact of bacteroides uniformis on fatty liver hemorrhagic syndrome in dawu golden phoenix laying hens: modulation of gut microbiota and arachidonic acid metabolism.do... by Yu Zhang (12946)

“…Moreover, targeted metabolomic analysis showed that supplementation of B. uniformis significantly elevated 6-keto-PGF_1α and AA levels, along with significantly reduced levels of thromboxane B₂ (TXB₂), leukotriene D₄ (LTD₄), 8-isoprostaglandin F_2α (8-iso-PGF_2α), 12S-hydroxyeicosatetraenoic acid (12S-HETE), 15S-hydroxyeicosatetraenoic acid (15S-HETE), 9-S-hydroxy-octadecadienoic acid (9S-HODE), and 13-S-hydroxy-octadecadienoic acid (13S-HODE) (p < 0.05). …”

Supplementary file 1_Responses of fish population structure to barrage re-opening in an estuarine ecosystem.docx by Jeong-Soo Gim (18058588)

“…</p>Results<p>During the OP, we observed shifts in fish distribution, including decreased proportions of non-indigenous species and altered habitat distributions. …”

Supplemental Material for Dhiman et al., 2025 by Pallavi Dhiman (21772823)

“…Furthermore, metabolic profiling showed significant changes in the accumulation of compounds influencing flavor and nutritional properties. …”