Search alternatives:
significantly altered » significantly affected (Expand Search), significantly elevated (Expand Search), significantly lower (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
altered decrease » altered release (Expand Search), observed decrease (Expand Search), teer decrease (Expand Search)
significantly altered » significantly affected (Expand Search), significantly elevated (Expand Search), significantly lower (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
altered decrease » altered release (Expand Search), observed decrease (Expand Search), teer decrease (Expand Search)
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1801
Data Sheet 1_N-acetylcysteine reduces prefrontal reactivity to cocaine cues in individuals with cocaine use disorder.pdf
Published 2025“…While N-acetylcysteine showed no impact on subjectively rated cocaine craving, neural cue reactivity in the superior frontal gyrus was significantly decreased under N-acetylcysteine compared to placebo.…”
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1802
Data Sheet 1_NLRP3 regulates epithelial barrier integrity and protects from airway hyperresponsiveness in experimental allergic asthma.pdf
Published 2025“…</p>Methods<p>Using an experimental model of allergic airway disease, NLRP3-deficient (NLRP3<sup>-/-</sup>) and wild-type (WT) mice were analyzed for AHR, mucus hyperplasia, airway inflammation and the alterations in the airway epithelium transcriptome.</p>Results<p>In comparison to WT mice, NLRP3<sup>-/-</sup> mice exhibited significantly enhanced AHR and mucus production, while eosinophilic airway inflammation was comparable. …”
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1803
Impact of acute binge-like ethanol exposure during the third-trimester equivalent on subicular interneurons in mice
Published 2025“…Adolescent neuronal density was significantly decreased in exposed males’ distal dorsal subiculum (<i>p</i> < .0001, g = −0.8). …”
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1804
Table 1_Mechanism of action of decitabine in treating acute lymphoblastic leukemia.docx
Published 2025“…Animal experimental results indicated that both DAC and doxorubicin substantially decreased tumor length, width, volume, and mass; however, DAC demonstrated significantly superior efficacy in inhibiting tumor growth compared to doxorubicin.…”
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1805
Supplementary Material for: Impact of the apolipoprotein E ε4 allele on cognition and omega-3 fatty acid levels in the plasma membrane of red blood cells in healthy elderly Japanes...
Published 2025“…The ratio of docosahexaenoic acid (DHA) to arachidonic acid was significantly decreased, and the erythrocyte eicosapentaenoic acid (EPA) and DHA levels tended to be reduced in APOE4 carriers. …”
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1806
Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis
Published 2025“…Obvious histopathological differences were detected in resistant and susceptible individuals in terms of inflammatory cells infiltration, and tissue dissociation of mucosal layer. 16S rRNA sequencing was performed to characterize the changes in intestinal microbial community, in which Vibrio increased but Stenotrophomonas, Chryseobacterium, Delftia, and Salinivibrio decreased in the susceptible group. RNA-seq analysis indicated that 1,986 differentially expressed genes (DEGs) were detected in the susceptible group, significantly more than 310 in the resistant group, when compared to the control group. …”
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1807
Table 1_Distinct vaginal microbiome and metabolome profiles in women with preterm delivery following cervical cerclage.docx
Published 2025“…Vaginal microbiome revealed that the proportion of beneficial bacteria (including Lactobacillus, [Ruminococcus] gnavus group, and Megamonas) significantly decreased in the PTB group, and the proportion of harmful bacteria (including Desulfovibrionaceae, Helicobacter, and Gardnerella) significantly increased, which is strongly related to the biochemical parameters of blood (white blood cells, neutrophils, NLR, and SIRI). …”
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1808
Data Sheet 1_The response regulator CrsR positively regulates ansamitocin P-3 biosynthesis in Actinosynnema pretiosum.docx
Published 2025“…Deletion of the response regulator gene crsR drastically decreased AP-3 production. RNA-seq revealed CrsR’s global regulatory role, significantly altering transcription of primary metabolic genes, especially those in purine metabolism. …”
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1809
Image 5_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Furthermore, lymphocyte subsets and cytokine detections were performed by flow cytometry to analyze the alteration of immune responses. Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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1810
Image 4_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Furthermore, lymphocyte subsets and cytokine detections were performed by flow cytometry to analyze the alteration of immune responses. Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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1811
Image 3_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Furthermore, lymphocyte subsets and cytokine detections were performed by flow cytometry to analyze the alteration of immune responses. Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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1812
Image 2_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Furthermore, lymphocyte subsets and cytokine detections were performed by flow cytometry to analyze the alteration of immune responses. Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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1813
Image 1_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Furthermore, lymphocyte subsets and cytokine detections were performed by flow cytometry to analyze the alteration of immune responses. Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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1814
Supplementary file 1_Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut micro...
Published 2025“…</p>Results<p>HSYA significantly inhibited HFD-induced weight gain and alleviated liver inflammation. …”
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1815
Image 2_Phage therapy for extensively drug resistant Acinetobacter baumannii infection: case report and in vivo evaluation of the distribution of phage and the impact on gut microb...
Published 2024“…Sequencing analysis revealed significant alterations in the microbiota composition at both the phylum and genus levels during phage therapy. …”
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1816
Image 1_Phage therapy for extensively drug resistant Acinetobacter baumannii infection: case report and in vivo evaluation of the distribution of phage and the impact on gut microb...
Published 2024“…Sequencing analysis revealed significant alterations in the microbiota composition at both the phylum and genus levels during phage therapy. …”
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1817
Table 1_Prior Trichinella spiralis infection protects against Schistosoma mansoni induced hepatic fibrosis.docx
Published 2024“…Furthermore, pre- infection with T. spiralis markedly reduced S. mansoni- induced hepatic fibrosis, as evidenced by decreased collagen deposition, low expression of α-SMA, and significantly reduced levels of IL-17, IL-1B, IL-6, TGF-B, IL-23, and TNF-α compared to mice infected with S. mansoni only.…”
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1818
C2CD3 is crucial for the localization of the LDR and DISCO complexes.
Published 2025“…Centriole diameter was not significantly altered (siCTRL: <i>n</i> = 44, 115 ± 24 nm; siC2CD3: <i>n</i> = 44, 123 ± 27 nm; <i>P</i> = 0.0564). …”
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1819
Table1_Association mapping for water use efficiency in soybean identifies previously reported and novel loci and permits genomic prediction.xlsx
Published 2024“…However, drought stress is the most significant factor that decreases soybean yield, and more than 90% of US soybean acreage is dependent on rainfall. …”
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1820
Table 1_Pig-L mediates virulence, biofilm formation, and oxidative stress tolerance in Clostridioides difficile.docx
Published 2025“…</p>Results<p>Deletion of the pig-L gene resulted in a significant reduction in C. difficile virulence, decreased biofilm formation, and increased susceptibility to oxidative stress. …”