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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
associated decrease » associated increase (Expand Search), associated disease (Expand Search), associated diseases (Expand Search)
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18601
Table 8_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
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18602
Image5_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff
Published 2024“…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”
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18603
Image 1_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif
Published 2024“…Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…”
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18604
Data Sheet 1_Evaluating the therapeutic potential of BSA-reduced mussel-derived selenium nanoparticles to mitigate copper sulfate-induced hepatic damage and neurodegeneration in a...
Published 2025“…Stabilized selenium nanoparticles reduced for 30 minutes (25 μg/ml) showed significant in vitro reactive oxygen species scavenging activity and improved in vivo antioxidant enzyme levels by decreasing lipid peroxidation and nitric oxide levels. …”
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18605
Data source.
Published 2025“…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …”
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18606
Image 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o...
Published 2025“…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …”
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18607
Data Sheet 1_Dysregulation of melatonin rhythm in Parkinson’s and Huntington’s disease: a systematic review and meta-analysis.docx
Published 2025“…In manifest HD, both amplitude [RoM = 0.92, 95% CI (0.81 to 1.02); p = 0.00] and acrophase [RoM = 0.92, 95% CI (0.07 to 1.78); p = 0.03] significantly decreased. PD patients with sleep disorders had significantly higher melatonin concentrations than the non-sleep disorder group, with a significant test group difference of p = 0.00. …”
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18608
Research Technology Flow Chart.
Published 2025“…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …”
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18609
Data Sheet 1_Andrographis paniculata restores gut health by suppressing inflammation and strengthening mucosal immunity.pdf
Published 2025“…</p>Results<p>ApEtOH significantly downregulated the chemokines RANTES, MCP-1, and ENA-78, reducing the pro-inflammatory cytokines TNF-α and IL-6 in vitro. …”
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18610
Table 2_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.xlsx
Published 2024“…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …”
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18611
Image 2_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif
Published 2024“…Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…”
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18612
Image1_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff
Published 2024“…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”
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18613
Data Sheet 1_Cultivar-specific responses of the citrus endophytic microbiome to Xanthomonas citri subsp. citri infection reveals Lysobacter as a key biocontrol taxon.xlsx
Published 2025“…Conversely, fungal community richness decreased in both cultivars post-inoculation, with notable cultivar-specific changes in the relative abundance of key genera. …”
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18614
Presentation1_Pressure-tolerant survival mechanism of Schizophyllum commune 20R-7-F01 isolated from deep sediments 2 kilometers below the seafloor.pdf
Published 2024“…By assessing the cell viability, biomass, and cell wall thickness changes of strain 20-7-1 under different HHP conditions, we observed that, compared to 0.1 MPa, strain 20-7-1 exhibited slower growth rates and decreased cell viability at 15 MPa and 35 MPa, yet demonstrated significant pressure tolerance. …”
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18615
Aquaporin and red cell O2 permeability
Published 2025“…We find that at 7°/10°C lack of AQP1 in the red cell membrane causes significant reductions of PO2, by 20% in human and by 37% in mouse red cells. …”
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18616
Data Sheet 8_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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18617
Image 1_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.jpeg
Published 2025“…Immunohistochemistry showed that HRG expression was decreased in HCC compared to normal tissues, whereas TUBA1B expression was elevated in HCC.…”
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18618
Data Sheet 3_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx
Published 2025“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”
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18619
Table 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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18620
Table 1_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx
Published 2025“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”