Table 1_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.docx by Shaolian Zang (11987905)

“…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …”

Image 3_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif by Shaolian Zang (11987905)

“…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …”

Image 2_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif by Shaolian Zang (11987905)

“…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …”

Image 1_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif by Shaolian Zang (11987905)

“…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …”

S1 Data - by Sunday O. Ochai (12083153)

“…Anthrax cases in 1990 were concentrated in the central and northern regions of KNP(excluding Pafuri), primarily affected kudus; while subsequent mortalities affected mostly impala and were restricted to the far north, in Pafuri. Significant correlations were found between kudu anthrax mortality and a decrease in NDVI, average temperature, SPI-6 and SPI-12 (Standardised Precipitation Index in various time intervals. …”

Table 1_Multiparametric MRI assessment of renal blood oxygenation, fat content, and hemodynamics in an animal model of metabolic dysfunction-associated steatotic liver disease.docx by Chao Wang (146527)

“…Aims<p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is a significant risk factor for chronic kidney disease. …”

Loss of parasympathetic cholinergic neurons innervating the liver. by Jiyeon Hwang (19747297)

“…(E, F) Summary plots showing a significant decrease in hepatic (control, <i>n</i> = 7 mice; experimental mice, <i>n</i> = 6 mice), but not plasma (control, <i>n</i> = 11 mice; experimental mice, <i>n</i> = 8 mice), ACh contents in ChAT^{Cre + AAVrg-FLEX-dtA} mice compared to the controls. …”

Table 1_Association of brain-derived neurotrophic factor levels at different trimesters and new-onset depressive symptom in the third trimester among pregnant women: a longitudinal... by Yue-rong Zhang (21838784)

“…</p>Conclusion<p>Overall, serum BDNF levels in the first, second, and third trimester were significantly associated with decreased PHQ-9 score and reduced risk of prenatal depressive symptoms. …”

Additional within-case comparison information. by Ryan J. Treves (13527735)

“…Our results suggest that the increase in sanctions was associated with decreases in violations with relatively low compliance costs (such as reporting violations), but that there may be considerable mismatch between the scale of penalties and compliance costs for keeping many types of pollutants within regulatory limits, and an underappreciation of critical factors like political pressure that are uncaptured by classical theory. …”

POTW sample summary. by Ryan J. Treves (13527735)

“…Our results suggest that the increase in sanctions was associated with decreases in violations with relatively low compliance costs (such as reporting violations), but that there may be considerable mismatch between the scale of penalties and compliance costs for keeping many types of pollutants within regulatory limits, and an underappreciation of critical factors like political pressure that are uncaptured by classical theory. …”

Deleting liver-innervating cholinergic neurons induces beiging of ingWAT. by Jiyeon Hwang (19747297)

“…Right panel: The mean cell area was significantly smaller in the experimental groups than in controls (control, <i>n</i> = 4 mice; experimental, <i>n</i> = 5 mice, unpaired <i>t</i> test, *<i>p</i> < 0.05). …”

Minimal data set. by Fu-Lin Yu (21446056)

“…Prolonged and excessive exposure to arsenic causes various toxic reactions, leading to diseases that significantly impact health and lifespan. Increasing evidence suggests that arsenic damages skeletal muscle tissue by reducing muscle mass and causing atrophy, thereby contributing to conditions such as respiratory and cardiovascular diseases, as well as diabetes. …”

Data Sheet 1_The association of diabetic retinopathy and diabetic kidney disease in patients with type 2 diabetes mellitus: a prospective observational research study.pdf by Yutong Wu (3130584)

“…Spearman’s correlation analysis revealed significant associations between each DKD indicator and the T2DM subgroups, with rs = 0.223, p = 0.001, for Hcy; rs = 0.452, p < 0.001, for CysC; and rs = 0.564, p < 0.001, for β2-MG. …”

Image 1_Assessment of microstructural abnormalities in gray and white matter of minimal hepatic encephalopathy patients using diffusion kurtosis imaging and their associations with... by Qing Sun (492552)

“…</p>Results<p>The TBSS analysis results showed that MHE patients had significantly decreased fractional anisotropy (FA) in the temporal part of the left superior longitudinal fasciculus and decreased kurtosis fractional anisotropy (KFA) in the left corticospinal tract and anterior thalamic radiation (p < 0.05, threshold-free cluster enhancement corrected). …”

Data Sheet 1_Altered immune cell profiles in blood of mature/peripheral T-cell leukemia/lymphoma patients: an EuroFlow study.docx by F. Javier Morán-Plata (18986483)

“…In contrast, SS/MF showed neutrophilia, associated with decreased numbers of dendritic cells and NK-cells, potentially reflecting their increased migration from blood to the skin. …”

Table 1_Association between platelet count and 30-day in-hospital mortality among intensive care unit patients with sepsis: a multicenter retrospective cohort study.docx by Jun Wang (5906)

“…</p>Conclusion<p>This large-scale, multicenter retrospective study has made a significant contribution to understanding the association between platelet count and mortality in patients with sepsis in intensive care units. …”

Data_Sheet_1_Joint association of serum sodium and frailty with mild cognitive impairment among hospitalized older adults with chronic diseases: a cross-sectional study.docx by Zhaozhao Hui (10221125)

“…Below 143 mmol/L, the risk of MCI was 1.38 (95% CI: 1.03–1.84) for per 1 SD decrease in serum sodium. Compared with the robust group, frailty was significantly associated with an increased risk of MCI (OR = 3.94, 95% CI: 1.92–8.10). …”

Table 1_Integrated gut microbiota and metabolomic profiling reveals key associations between amino acid levels and gut microbial composition in patients with obesity.docx by Musen Qi (22489075)

“…Metabolomic analysis revealed that in patients with obesity, the abundance of carnosine (log2FC = 1.16, FDR = 0.0016, VIP = 0.707), creatinine (log2FC = 0.21, FDR = 0.0009, VIP = 2.02), and cystine (log2FC = 0.55, FDR = 0.009, VIP = 1.47) was significantly increased compared with that in the controls; in contrast, that of ornithine (log2FC = −0.59, FDR = 0.0009, VIP = 1.19), citrulline (log2FC = −0.59, FDR = 0.0003, VIP = 0.707), glycine (log2FC = −0.54, FDR = 0.0003, VIP = 1.41), and serine (log2FC = −0.38, FDR = 0.0019, VIP = 1.62) was significantly decreased. …”

Table 1_Regional and age-specific global trends associated with infectious diarrhea in children under 14 years old caused by pathogenic microorganisms in 2021.docx by Tuanjie Wang (6619406)

Data Sheet 2_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf by Meng Yi (7853249)

“…IL1R1 was highly expressed in specific diabetes-associated NP subpopulations and showed significant positive correlation with neutrophil infiltration. …”