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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
associated decrease » associated increase (Expand Search), associated disease (Expand Search), associated diseases (Expand Search)
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3961
Data Sheet 1_Luteolin induces apoptosis in Philadelphia chromosome-positive acute lymphoblastic leukemia cell by regulating the PI3K/AKT signaling pathway.zip
Published 2025“…Luteolin (LUT), a natural flavonoid compound, has demonstrated significant anticancer activity. However, its mechanism of action in the context of Ph + ALL remains poorly understood. …”
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3962
Data Sheet 1_CD8+ T cells mediate the impact of gut dysbiosis and short-chain fatty acid deficiency on accelerated arthritis progression in collagen-induced arthritis mice.docx
Published 2025“…CD8<sup>+</sup> T cells were significantly increased in mesenteric lymph nodes (MLN) and intestinal mucosa (IM). …”
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3963
Image 2_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.tif
Published 2025“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”
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3964
Table 3_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.xlsx
Published 2025“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”
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3965
Upper extremity orthopedic softball injuries presenting to the emergency department: epidemiology across the lifespan
Published 2024“…The average incidence rate of UE injuries from 2012–2021 was 187.9 per 100,000 persons, with a significant decrease in injury incidence across the timespan (<i>p</i> < .001). …”
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3966
Table 2_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.xlsx
Published 2025“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”
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3967
Computational insights into <i>PKCθ</i> non-synonymous SNPs: from structural changes to functional implications
Published 2025“…Conservation profiling highlighted the evolutionary significance of these residues, indicating their critical roles in protein function. …”
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3968
Data Sheet 1_Quantitative EEG and its relationship with attentional control in patients with anxiety disorders.docx
Published 2024“…Correlation analysis revealed that decreased beta power and increased TBR were significant association between attentional control deficits in ANX.…”
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3969
Figure 1 from Tumor-Immune Signatures of Treatment Resistance to Brentuximab Vedotin with Ipilimumab and/or Nivolumab in Hodgkin Lymphoma
Published 2025“…<b>F,</b> Line and boxplot examples of significant (<i>P</i> < 0.05 & FDR < 0.05) proteins associated with response (blue) or nonresponse (red) over time.…”
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3970
Data Sheet 1_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf
Published 2025“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”
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3971
Table 1_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.docx
Published 2025“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”
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3972
Image 3_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf
Published 2025“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”
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3973
Table 2_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).xlsx
Published 2025“…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …”
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3974
Table 1_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.xlsx
Published 2025“…<p>Impaired intestinal epithelial barrier function is closely associated with the pathogenesis of ulcerative colitis (UC). …”
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3975
Image 2_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.tif
Published 2025“…<p>Impaired intestinal epithelial barrier function is closely associated with the pathogenesis of ulcerative colitis (UC). …”
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3976
Table 1_Emergency department utilization among youth in foster care: benefits of a patient-centered medical home.pdf
Published 2025“…Compared to before the PCMH, ED utilization was significantly lower during engagement with the PCMH [IRR: 0.62 (95% CI: 0.54–0.70)]. …”
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3977
MaMsb2, a signaling mucin, is involved in conidiation, stress tolerances, and virulence in the entomopathogenic fungus <i>Metarhizium acridum</i>
Published 2025“…Additionally, the <i>MaMsb2</i>-disruption bring about the significantly reduced tolerances to various adversities in <i>M. acridum</i>. …”
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3978
Image 5_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf
Published 2025“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”
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3979
Table 3_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).xlsx
Published 2025“…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …”
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3980
Table 1_Integrated multi-omics analysis reveals that Gongying San ameliorates subclinical mastitis by modulating intestinal microbiota and metabolites in dairy cows.docx
Published 2025“…</p>Results<p>GYS significantly increased milk yield, lactose and milk protein, and decreased somatic cell count (SCC) in milk from cows with SCM. …”