Table 1_Simultaneous regulation of both lignin and cellulose biosynthesis modifies xylem fiber properties in Populus.xlsx by Jian Li (41607)

“…</p>Results and discussion<p>The transgenic plants exhibited decreased lignin content and a significant increase in cellulose content. …”

<b>Gene x environment interactions as drivers of lifespan variation in nematodes</b> by Justin Havird (2812975)

“…Both the genetic strains and phytochemicals were associated with mitochondrial function. We found significant effects of genetic background (although not always as precited from previous studies), chemical treatment, and their interactions (GxE) that explained variation in lifespan. …”

Image 1_Endocrine-disrupting effects of environmental BPS and PFOS on human brain organoid development.tiff by Andrea Di Credico (13137135)

“…Importantly, TUNEL assay confirmed the absence of significant cytotoxicity. BPS exposure was associated with reduced ERβ, GPER, and phosphorylated Akt expression, suggesting a possible involvement of estrogen-related pathways. …”

Table 1_Dynamic changes of gut microbiota between the first and second trimester for women with gestational diabetes mellitus and their correlations with BMI: a nested cohort study... by Shilin Zhong (9588065)

“…In the second trimester, GDM individuals showed increased abundance of Fusobacteriota and Firmicutes_D, and genera including Fusobacterium_A and Fournierella, while Anaerotruncus and others decreased (P<0.05). Inflammation-associated genera like Gemmiger_A_73129 and Enterocloster increased, while Megamonas decreased in overweight or obese GDM women, which was not identified in normal-weight women. …”

Supplementary file 1_Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005–2024.docx by Zheyuan Ding (4281394)

“…This study aims to assess the potential independent risks associated with age, period, and birth cohort for the reported incidence of syphilis in Eastern China.…”

Image 1_Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005–2024.jpeg by Zheyuan Ding (4281394)

“…This study aims to assess the potential independent risks associated with age, period, and birth cohort for the reported incidence of syphilis in Eastern China.…”

Data Sheet 1_Immune monitoring of trabectedin therapy in refractory soft tissue sarcoma patients - the IMMUNYON study.pdf by Paulo Rodrigues-Santos (3424613)

“…Therapy duration revealed 59.1% treated for less than 12 months (<12M) and 40.9% for 12 or more months (≥12M). A significant PFS improvement was observed in SD versus PD patients (p=0.0154), while therapy duration showed no effect (p=0.5433). …”

Image 3_Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005–2024.jpeg by Zheyuan Ding (4281394)

“…This study aims to assess the potential independent risks associated with age, period, and birth cohort for the reported incidence of syphilis in Eastern China.…”

Image 1_Temporal trends of community and climate changes in the anthropocene: 21-year dynamics of four major functional groups in a rocky intertidal habitat along the Pacific coast... by Hiroki Sato (105731)

“…We aimed to examine the 21-year trends in regional abundance at both functional-group and species levels, plus their driving mechanisms and their dependence on species properties (thermal niche, calcification status, and vertical niche). Significant temporal trends in abundance were detected at functional-group levels for benthic algae (increasing) and herbivores and carnivores (both decreasing); they followed the temporal population trends of the dominant species. …”

Table 1_Temporal trends of community and climate changes in the anthropocene: 21-year dynamics of four major functional groups in a rocky intertidal habitat along the Pacific coast... by Hiroki Sato (105731)

“…We aimed to examine the 21-year trends in regional abundance at both functional-group and species levels, plus their driving mechanisms and their dependence on species properties (thermal niche, calcification status, and vertical niche). Significant temporal trends in abundance were detected at functional-group levels for benthic algae (increasing) and herbivores and carnivores (both decreasing); they followed the temporal population trends of the dominant species. …”

Soil carbon, nitrogen, and phosphorus stoichiometry in subtropical forests of Zhejiang, China by Tonggui Wu (20215883)

“…<p dir="ltr"><a href="" target="_blank">Soil carbon (C), nitrogen (N), and phosphorus (P) stoichiometry in regional forests has garnered significant attention, yet reported distribution patterns and variation often show discrepancies and even contradictions. …”

Image 2_Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005–2024.jpeg by Zheyuan Ding (4281394)

“…This study aims to assess the potential independent risks associated with age, period, and birth cohort for the reported incidence of syphilis in Eastern China.…”

Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf by Faruk Hossen (20275670)

“…Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …”

Table 4_Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential... by Daniel Leduc (9191783)

“…These spatially consistent patterns reflect the influence of methane seepage, which appears limited to the inner 150-200 m radius of each area, on nematode abundance via input of chemosynthetic food sources. We found significant differences in nematode community structure among all three areas, with most of the heterogeneity in community structure between the shallow Urutī South area and deeper Maungaroa and Glendhu areas, and differences among nematode communities of high, medium and low abundance associated with site-specific gradients in methane seepage. …”

Table 6_Global burden of amputation among children and adolescents from 1990 to 2021: systematic analysis of the Global Burden of Disease study 2021.xlsx by Tao Zhang (43681)

“…Introduction<p>Amputation among children and adolescents, with its substantial physical, psychological, and economic impacts, remains a significant global health issue.</p>Objectives<p>This study uses data from the Global Burden of Disease (GBD) to examine trends in amputation burden among youth aged 0–19 from 1990 to 2021.…”

Table 3_Global burden of amputation among children and adolescents from 1990 to 2021: systematic analysis of the Global Burden of Disease study 2021.xlsx by Tao Zhang (43681)

“…Introduction<p>Amputation among children and adolescents, with its substantial physical, psychological, and economic impacts, remains a significant global health issue.</p>Objectives<p>This study uses data from the Global Burden of Disease (GBD) to examine trends in amputation burden among youth aged 0–19 from 1990 to 2021.…”

Image 7_Systemic immune inflammatory index and mortality in chronic kidney disease.tif by Yanshuang Ma (22176478)

“…Higher SII levels correlated with decreased survival and longevity. In CKD patients over 45 years, SII reliably predicted all-cause mortality (statistically significant) and was linked to cardiovascular and cancer deaths (not statistically significant).…”

Image 11_Global burden of amputation among children and adolescents from 1990 to 2021: systematic analysis of the Global Burden of Disease study 2021.png by Tao Zhang (43681)

“…Introduction<p>Amputation among children and adolescents, with its substantial physical, psychological, and economic impacts, remains a significant global health issue.</p>Objectives<p>This study uses data from the Global Burden of Disease (GBD) to examine trends in amputation burden among youth aged 0–19 from 1990 to 2021.…”

Table 1_Global burden of amputation among children and adolescents from 1990 to 2021: systematic analysis of the Global Burden of Disease study 2021.xlsx by Tao Zhang (43681)

“…Introduction<p>Amputation among children and adolescents, with its substantial physical, psychological, and economic impacts, remains a significant global health issue.</p>Objectives<p>This study uses data from the Global Burden of Disease (GBD) to examine trends in amputation burden among youth aged 0–19 from 1990 to 2021.…”

Image 9_Global burden of amputation among children and adolescents from 1990 to 2021: systematic analysis of the Global Burden of Disease study 2021.png by Tao Zhang (43681)

“…Introduction<p>Amputation among children and adolescents, with its substantial physical, psychological, and economic impacts, remains a significant global health issue.</p>Objectives<p>This study uses data from the Global Burden of Disease (GBD) to examine trends in amputation burden among youth aged 0–19 from 1990 to 2021.…”