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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
associated decrease » associated increase (Expand Search), associated disease (Expand Search), associated diseases (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
associated decrease » associated increase (Expand Search), associated disease (Expand Search), associated diseases (Expand Search)
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Characteristics of the included studies.
Published 2025“…The combined findings showed that high-dose TXA was associated with a significant reduction in intraoperative blood loss [weighted mean difference (WMD) = -215.48, 95% confidence interval (CI) (-367.58, -63.37), P < 0.001], as well as a decreased likelihood of transfusion [risk ratio (RR) = 0.40, 95% CI (0.30, 0.53), P < 0.001]. …”
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Summary of results.
Published 2025“…The combined findings showed that high-dose TXA was associated with a significant reduction in intraoperative blood loss [weighted mean difference (WMD) = -215.48, 95% confidence interval (CI) (-367.58, -63.37), P < 0.001], as well as a decreased likelihood of transfusion [risk ratio (RR) = 0.40, 95% CI (0.30, 0.53), P < 0.001]. …”
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Bias risk assessments for each RCT study.
Published 2025“…The combined findings showed that high-dose TXA was associated with a significant reduction in intraoperative blood loss [weighted mean difference (WMD) = -215.48, 95% confidence interval (CI) (-367.58, -63.37), P < 0.001], as well as a decreased likelihood of transfusion [risk ratio (RR) = 0.40, 95% CI (0.30, 0.53), P < 0.001]. …”
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The flow chart of studies selecting.
Published 2025“…The combined findings showed that high-dose TXA was associated with a significant reduction in intraoperative blood loss [weighted mean difference (WMD) = -215.48, 95% confidence interval (CI) (-367.58, -63.37), P < 0.001], as well as a decreased likelihood of transfusion [risk ratio (RR) = 0.40, 95% CI (0.30, 0.53), P < 0.001]. …”
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Funnel plots for intraoperative blood loss.
Published 2025“…The combined findings showed that high-dose TXA was associated with a significant reduction in intraoperative blood loss [weighted mean difference (WMD) = -215.48, 95% confidence interval (CI) (-367.58, -63.37), P < 0.001], as well as a decreased likelihood of transfusion [risk ratio (RR) = 0.40, 95% CI (0.30, 0.53), P < 0.001]. …”