Image 4_Entropy as a marker of physiological transition during pediatric cardiopulmonary exercise testing.jpeg حسب Kaleigh O’Hara (22750082)

"…In addition to sex and age group comparisons, we examined SampEn before and after the midpoint of each participant’s CPET to assess how SampEn changes as exercise intensity increases. We corroborated previous findings that SampEn decreases in the later half of CPET for healthy pediatric participants for oxygen uptake (V̇O2), carbon dioxide output (V̇CO2), ventilation (V̇E), and heart rate (HR). …"

Data Sheet 1_Effect of liraglutide on the dysglycemia, inflammation, and gut microbiota in prediabetic KKay mice.docx حسب Ying Zhang (40767)

"…Prediabetic mice presented significantly increased body weights, blood glucose levels, and inflammatory factor levels and decreased GLP-1 levels. …"

Data Sheet 1_Involvement of long non-coding RNA (lncRNA) MALAT1 in shear stress regulated adipocyte differentiation.docx حسب Justin Caron (21249173)

"…By leveraging a novel gapmer double stranded locked nuclei acid nanobiosensor, we showed that shear stress inhibits MALAT1 expression, with significantly reduced fluorescence intensity. Our findings indicate that shear stress influences adipocyte differentiation mainly through the downregulation of MALAT1, highlighting a significant interplay between biophysical cues and lncRNAs. …"

Table 1_Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization.docx حسب Lianjie Ruan (22660265)

"…To evaluate its therapeutic potential, we administered exogenous carnosine in both models and assessed its effects on body weight, inflammatory cytokine expression, and histopathological changes.</p>Results<p>Carnosine supplementation significantly improved body weight maintenance, reduced the expression of pro-inflammatory cytokines, and attenuated histological lung damage in both LPS- and papain-induced lung injury models. …"

Table 2_Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization.xlsx حسب Lianjie Ruan (22660265)

"…To evaluate its therapeutic potential, we administered exogenous carnosine in both models and assessed its effects on body weight, inflammatory cytokine expression, and histopathological changes.</p>Results<p>Carnosine supplementation significantly improved body weight maintenance, reduced the expression of pro-inflammatory cytokines, and attenuated histological lung damage in both LPS- and papain-induced lung injury models. …"

Data Sheet 1_Trifolin inhibits the calcium-driven contraction pathway in vascular smooth muscle.pdf حسب Renfeng Li (126284)

"…<p>Trifolin, a bioactive component of the Qingda granule, has demonstrated significant antihypertensive potential; however, its precise mechanisms of action remain largely unknown. …"

Supplementary file 1_Prolonged effect of antibiotic therapy on the gut microbiota composition, functionality, and antibiotic resistance genes’ profiles in healthy stool donors.zip... حسب Ramin Karimianghadim (21288299)

"…No significant increase in clinically important ARGs was detected.…"

Data Sheet 1_Mechanism of salidroside promoting testosterone secretion induced by H2O2 in TM3 Leydig cells based on metabolomics and network pharmacology.zip حسب Zixu Wang (6297470)

"…The study investigated the oxidative damage in TM3 cells induced by H₂O₂ and demonstrated that salidroside significantly decreased the levels of ROS and MDA, while increasing the levels of testosterone, SOD, GSH. …"

Image 1_Entropy as a marker of physiological transition during pediatric cardiopulmonary exercise testing.jpeg حسب Kaleigh O’Hara (22750082)

"…In addition to sex and age group comparisons, we examined SampEn before and after the midpoint of each participant’s CPET to assess how SampEn changes as exercise intensity increases. We corroborated previous findings that SampEn decreases in the later half of CPET for healthy pediatric participants for oxygen uptake (V̇O2), carbon dioxide output (V̇CO2), ventilation (V̇E), and heart rate (HR). …"

Image 2_Entropy as a marker of physiological transition during pediatric cardiopulmonary exercise testing.jpeg حسب Kaleigh O’Hara (22750082)

"…In addition to sex and age group comparisons, we examined SampEn before and after the midpoint of each participant’s CPET to assess how SampEn changes as exercise intensity increases. We corroborated previous findings that SampEn decreases in the later half of CPET for healthy pediatric participants for oxygen uptake (V̇O2), carbon dioxide output (V̇CO2), ventilation (V̇E), and heart rate (HR). …"

Supplementary file 1_Saltmarsh reclamation enhances plant species richness and reduces soil macrofaunal biomass by regulating soil properties through elevation.docx حسب Guangzhi Zhang (471563)

"…<p>Globally, saltmarsh reclamation results in significant losses of coastal wetlands. However, the impacts on above- and below-ground biodiversity and the underlying mechanisms remain poorly understood. …"

Table 1_Soil bacterial community composition but not alpha diversity altered along a gradient of Spartina alterniflora invasion on the coast of Yellow Sea, China.docx حسب Li Yang (6520)

"…Furthermore, no significant changes were observed across different soil depths. …"

Table 1_Moso bamboo invasion alters soil microbial nutrient limitation by modifying plant diversity and soil nutrient cycling in subtropical forest.docx حسب Jiannan Wang (154792)

"…Soil total organic carbon (TOC), total nitrogen (TN), available phosphorus (AP), and available potassium (AK) all decreased significantly with increasing invasion intensity. …"

Data Sheet 1_Impacts of DRG point-based payment system on healthcare resource utilization and provider behavior: a pilot quasi-experimental study in China.docx حسب Xiao Huang (223709)

"…No significant changes were observed in CCI or 14-day and 90-day readmission rates, whereas 30-day readmissions fell by 2.0% (p < 0.05). …"

This is raw data of IL-1β ELISA. حسب Farzad Nasri (8941850)

"…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …"

This is raw data of IL-10 real-time PCR. حسب Farzad Nasri (8941850)

"…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …"

This is raw data of Gal-9 real-time PCR. حسب Farzad Nasri (8941850)

"…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …"

This is raw data of IL-10 ELISA. حسب Farzad Nasri (8941850)

"…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …"

Supplementary file 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burd... حسب Bo Peng (273834)

"…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …"

This is raw data of NF-κB real-time PCR. حسب Farzad Nasri (8941850)

"…</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …"