يعرض 6,161 - 6,180 نتائج من 6,596 نتيجة بحث عن '(( significant decrease decrease ) OR ( significantly change decrease ))~', وقت الاستعلام: 0.40s تنقيح النتائج
  1. 6161

    Supplementary file 5_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx حسب Yuhui Zhang (399617)

    منشور في 2025
    "…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
  2. 6162

    Table 1_Co-frequency or contrary? The effects of Qiwei Baizhu Powder and its bioactive compounds on mucosa-associated microbiota of mice with antibiotic-associated diarrhea.docx حسب Zeli Zhang (3422570)

    منشور في 2024
    "…The results showed that QWBZP-TG significantly altered the diversity, structure, and abundance of MAM in the AAD mice. …"
  3. 6163

    <b>Increasing ECM tree dominance enhances </b><b>soil </b><b>lignin </b><b>phenols </b><b>but suppresses microbial necromass contribution to soil organic carbon in a subtropical </... حسب Lu Mengzhen (20146224)

    منشور في 2025
    "…Our results indicated that ECM% did not affect SOC content but significantly altered SOC composition. Specifically, a higher ECM% promoted accumulation of plant-derived C and reduced microbial-derived C. …"
  4. 6164

    Table 2_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a... حسب Linxi Qian (555385)

    منشور في 2025
    "…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …"
  5. 6165

    Table 1_Optimization of drying parameters and texture properties of winter jujube slices by radio frequency combined with hot air.xlsx حسب Yang Li (7082)

    منشور في 2025
    "…The results showed as follows: (1) Plate spacing, RF application, and interval time all significantly affected the drying properties in the single-factor test (p < 0.05). …"
  6. 6166

    Dynamine 3 as a diagnostic and prognostic biomarker in pancreatic cancer: Implications for early detection and targeted therapy حسب Fatih Yay (20606054)

    منشور في 2025
    "…</p> <p>In the pancreatic adenocarcinoma (PAAD) cohort, DNM3 gene expression was higher in tumor samples, and there was no significant difference in expression among cancer stages. …"
  7. 6167

    Data Sheet 1_Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study.docx حسب Heinz Wiendl (237353)

    منشور في 2025
    "…IgG and IgM levels remained above the lower limits of normal in most participants. sNfL levels decreased, remaining reduced by M24. Significant reductions in the annualized combined unique active lesion count occurred from M2 onwards. …"
  8. 6168

    Data Sheet 2_Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study.csv حسب Heinz Wiendl (237353)

    منشور في 2025
    "…IgG and IgM levels remained above the lower limits of normal in most participants. sNfL levels decreased, remaining reduced by M24. Significant reductions in the annualized combined unique active lesion count occurred from M2 onwards. …"
  9. 6169

    Image 1_Bacterial peptidoglycan levels have brain area, time of day, and sleep loss-induced fluctuations.jpg حسب Erika L. English (21725081)

    منشور في 2025
    "…Herein, we report murine brain PG levels in multiple brain areas within the context of animals’ rest-wake cycles and after sleep loss. Significant time-of-day changes in brain PG levels occurred in all brain areas; lowest levels occurred during the transition from rest to wake periods, at zeitgeber time 12 (ZT12). …"
  10. 6170

    Image 2_Bacterial peptidoglycan levels have brain area, time of day, and sleep loss-induced fluctuations.jpg حسب Erika L. English (21725081)

    منشور في 2025
    "…Herein, we report murine brain PG levels in multiple brain areas within the context of animals’ rest-wake cycles and after sleep loss. Significant time-of-day changes in brain PG levels occurred in all brain areas; lowest levels occurred during the transition from rest to wake periods, at zeitgeber time 12 (ZT12). …"
  11. 6171

    Image 2_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff حسب Juliana R. Zampieri (22261441)

    منشور في 2025
    "…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.</p>Conclusion<p>While loss of p35 resulted in minor changes in phenotype, there were decreases in ARG-1 production and STAT3 phosphorylation, increased metabolism, and dramatically reduced antigen processing by M0, M1 or M2. …"
  12. 6172

    Data Sheet 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.docx حسب Lillia A. Baird (10575941)

    منشور في 2025
    "…Peripheral NK and CD8+ T cells were decreased dose-dependently. Interestingly, spinal cord infiltrating NK cells increased with low-dose tofacitinib, though no other changes in neuroinflammation were observed. …"
  13. 6173

    Image 1_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff حسب Juliana R. Zampieri (22261441)

    منشور في 2025
    "…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.</p>Conclusion<p>While loss of p35 resulted in minor changes in phenotype, there were decreases in ARG-1 production and STAT3 phosphorylation, increased metabolism, and dramatically reduced antigen processing by M0, M1 or M2. …"
  14. 6174

    Full name and abbreviation. حسب Yuanqiang Lv (20623742)

    منشور في 2025
    "…</p><p>Results and conclusion</p><p>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group’s SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …"
  15. 6175

    Table 2_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx حسب Lillia A. Baird (10575941)

    منشور في 2025
    "…Peripheral NK and CD8+ T cells were decreased dose-dependently. Interestingly, spinal cord infiltrating NK cells increased with low-dose tofacitinib, though no other changes in neuroinflammation were observed. …"
  16. 6176

    The animal experimental protocol. حسب Yuanqiang Lv (20623742)

    منشور في 2025
    "…</p><p>Results and conclusion</p><p>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group’s SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …"
  17. 6177

    Supplementary Material for: Race/Ethnic Differences in In-Hospital Mortality after Acute Ischemic Stroke حسب Sun P.Y. (20106159)

    منشور في 2024
    "…Introduction: Stroke mortality has declined, with differential changes by race; stroke is now the 5th leading cause of death overall, but 2nd leading cause of death in Black individuals. …"
  18. 6178

    Image 3_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff حسب Juliana R. Zampieri (22261441)

    منشور في 2025
    "…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.</p>Conclusion<p>While loss of p35 resulted in minor changes in phenotype, there were decreases in ARG-1 production and STAT3 phosphorylation, increased metabolism, and dramatically reduced antigen processing by M0, M1 or M2. …"
  19. 6179

    Table 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx حسب Lillia A. Baird (10575941)

    منشور في 2025
    "…Peripheral NK and CD8+ T cells were decreased dose-dependently. Interestingly, spinal cord infiltrating NK cells increased with low-dose tofacitinib, though no other changes in neuroinflammation were observed. …"
  20. 6180

    Data Sheet 1_Allicin ameliorates acute myocardial infarction in rats by modulating calcium homeostasis in cardiomyocytes through the induction of hydrogen sulfide production.docx حسب Weiyu Liu (3879487)

    منشور في 2025
    "…</p>Results<p>The results indicate that allicin significantly enhanced cardiac function, raised H<sub>2</sub>S levels in myocardial tissue and serum, reduced necrosis tissue size, decreased myocardial enzyme levels, and improved myocardial pathological changes. …"