بدائل البحث:
significantly clustered » significantly altered (توسيع البحث), significant clusters (توسيع البحث), significantly restored (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significantly clustered » significantly altered (توسيع البحث), significant clusters (توسيع البحث), significantly restored (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
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641
Table 1_Unraveling the anti-inflammatory effects of Mediterranean diet in patients with cancer remission.xlsx
منشور في 2025"…After dietary intervention, a significant reduction in specific inflammatory and metabolic biomarkers was observed, with distinct effects depending on tumor type. …"
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642
Table 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
منشور في 2025"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"
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643
Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
منشور في 2025"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"
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644
Data Sheet 1_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.csv
منشور في 2025"…A prognostic risk score model based on two genes was then established. Significant differences in immune cell infiltration were observed between high-risk and low-risk groups. …"
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645
Data Sheet 1_Unraveling the anti-inflammatory effects of Mediterranean diet in patients with cancer remission.pdf
منشور في 2025"…After dietary intervention, a significant reduction in specific inflammatory and metabolic biomarkers was observed, with distinct effects depending on tumor type. …"
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646
The role of IRF-1 in mediating T-cell immune imbalance in systemic lupus erythematosus and the construction of a diagnostic model
منشور في 2025"…Six machine learning models were trained and validated in four independent cohorts. scRNA-seq revealed significant downregulation of IRF-1 in T-cell subsets (central memory CD8⁺, Th17) during active SLE, with compensatory overexpression in remission—validated clinically. …"
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647
Image 1_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.jpeg
منشور في 2025"…A prognostic risk score model based on two genes was then established. Significant differences in immune cell infiltration were observed between high-risk and low-risk groups. …"
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648
Data Sheet 1_Spatial–temporal evolution and associated factors of older adult care institutions in Shanghai.xlsx
منشور في 2025"…</p>Results<p>The number of older adult care institutions in Shanghai has seen significant growth over the past 20 years, increasing fourfold due to the rise in both public and private facilities. …"
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649
Supplementary Material for: Leveraging NLP for Psychiatric Phenotyping from Spanish EHR: Enabling the Investigation of Transdiagnostic Symptom Profiles at Scale
منشور في 2025"…The COMBINED algorithm improved overall recall, without significantly decreasing precision (F1 of 0.78 and 0.77 on HOMO and CSJDM, respectively). …"
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650
Table1_Sucrose synthase gene family in common bean during pod filling subjected to moisture restriction.docx
منشور في 2024"….), leaf photosynthesis is significantly reduced under drought conditions. Previous studies have shown that some drought-tolerant cultivars use the pod walls to compensate the decreased photosynthesis rate in leaves by acting as temporary reservoirs of carbohydrates to support seed filling. …"
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651
Data Sheet 1_Top motor and non-motor complaints in patients with Parkinson's disease.docx
منشور في 2025"…Cognitive impairment was a significant predictor of non-motor symptoms in their top three tiers [odds ratio [OR]: 3.88 (95% CI: 1.647 to 9.169)]. …"
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652
DataSheet1_Strict biennial lifecycle and anthropogenic interventions affect temporal genetic differentiation in the endangered endemic plant, Pedicularis hallaisanensis.docx
منشور في 2024"…Other cluster analyses also showed that a microhabitat under historical anthropogenic interventions contained lowered genetic diversity due to a decreased genetic distance between odd-year and even-year flowering cohorts (p < 0.05). …"
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653
Image 2_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff
منشور في 2025"…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…"
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654
Image 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff
منشور في 2025"…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…"
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655
Data Sheet 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.zip
منشور في 2025"…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…"
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656
Changes in dorsal-ventral patterning of CA1 in COUP-TFI mutant hippocampus.
منشور في 2025"…The Dcn/Wfs1 ratio was significantly decreased in the cKO and increased in the cTG. …"
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657
Dynamic changes in mRNA stability.
منشور في 2025"…To visualize RSCU values across different clusters, a z-score normalization for cell lines or tissues was applied using the eq. (1) in Methods. …"
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658
Experimental protocol and behavioral evidence of perceptual learning.
منشور في 2025"…The shaded area represents the standard error of the mean. Significant clusters for the main effect of PRE/post training, as determined by cluster mass permutation two-tailed tests, are indicated with rectangles (p < 0.05 and p < 0.1). …"
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659
Broader frequency tuning in auditory cortex of <i>Fmr1</i> KO rats despite unaltered subcortical tuning properties.
منشور في 2025"…Boxplots dots represent individual multiunit clusters. All other values are means ± SEM. **<i>p</i> < 0.01, ***<i>p</i> < 0.0001, ns = not significant. …"
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660
A Locally Linear Dynamic Strategy for Manifold Learning.
منشور في 2025"…In contrast to alignment modulation, the change in the spectrum is largely non-selective. exhibits no significant change for both signal-oriented (blue) and noise-oriented (orange) modes. …"