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significantly declined » significant decline (Expand Search), significantly delayed (Expand Search), significantly decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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17621
Image 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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17622
Data Sheet 1_Increased epicardial tissue and reduced TAPSE and MAPSE scores in borderline personality disorders. Early indicators for cardiovascular risk?.pdf
Published 2025“…Additionally, significant decreases in right (TAPSE) and left (MAPSE) ventricular function, albeit within the normal range, were measured in BPD patients. …”
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17623
Table 1_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
Published 2025“…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …”
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17624
Table 10_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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17625
Data Sheet 1_Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue.d...
Published 2025“…</p>Results<p>Our findings revealed that OB EVs induced significant phosphorylation of STAT3, a key signaling molecule in cancer progression, and promoted increased cell migration, dependent on fatty acid oxidation (FAO). …”
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17626
Table 3_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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17627
Table6_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx
Published 2024“…In the sensitivity analysis, the A-level usage rate decreased to one-third and the B-level usage rate increased by 2–3 times. …”
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17628
Table 1_LpxR and PagL expression in live attenuated auxotrophic Pseudomonas aeruginosa vaccines modulates lipid A reactogenicity in vitro while preserving immunogenicity.docx
Published 2025“…Both mutant strains showed decreased TLR4 activation in vitro as compared to the wild type. …”
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17629
Image 3_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..jpeg
Published 2025“…The polyphenolic composition of the two cultivars significantly changed depending on the type of LEDs used. …”
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17630
Table4_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx
Published 2024“…In the sensitivity analysis, the A-level usage rate decreased to one-third and the B-level usage rate increased by 2–3 times. …”
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17631
DataSheet1_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf
Published 2024“…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…”
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17632
Table 5_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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17633
Counting results on DRPD dataset.
Published 2024“…At the same time, the model size was reduced by 9.3%, and the number of model layers was decreased, reducing computational costs and storage requirements. …”
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17634
Supplementary Material for: Novel Protocol for the Use of Advanced Hybrid Closed-Loop System in Adolescents Engaged in Contact Sports.
Published 2024“…After starting AHCL, the average participant time spent in the target glucose range (70-180mg/dL) was 79.34±8.46%, and no significant change was observed during the camp (mean difference +0.79±8.24%, p=0.7581). …”
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17635
Tectonic and metallogenic processes along the east Tethyan metallogenic domain (Lhasa-southern Tibet, Kohistan island arc and Chagai magmatic belt): a perspective review
Published 2025“…In the Lhasa terrane, fertile Miocene adakite-like intrusions originated from partial melting of thickened mafic lower crust, while ore-barren adakite characterized by relatively lower εNd(t), higher <sup>87</sup>Sr/<sup>86</sup>Sr(i), and decreased fluid-sensitive element ratios (Ba/La, Pb/Ce, Sr/Nd), indicating reduced slab-derived fluid input and increased contributions from ancient basement crust. …”
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17636
Quantitative results on RFRB dataset.
Published 2024“…At the same time, the model size was reduced by 9.3%, and the number of model layers was decreased, reducing computational costs and storage requirements. …”
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17637
Data Sheet 2_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx
Published 2025“…Rutin administration significantly alleviated LPS-induced lung injury, reducing oxidative stress, apoptosis, and proinflammatory cytokine levels (IL-6, IL-1β, TNF-α). …”
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17638
Table 1_Obstetric and perinatal outcomes in pregnancies conceived with donor versus partner sperm: a systematic review and meta-analysis.docx
Published 2025“…Donor sperm was linked to better clinical pregnancy rates (RR 1.27, 95% CI 1.08–1.48) and decreased incidences of biochemical pregnancy (RR 0.85, 95% CI 0.81–0.88), miscarriage (RR 0.91, 95% CI 0.84–1.00), very preterm birth (RR 0.88, 95% CI 0.80–0.96), and very low birth weight (RR 0.89, 95% CI 0.81–0.98) compared with partner sperm. …”
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17639
Table 2_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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17640
Data Sheet 1_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.xlsx
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…”