Data Sheet 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.docx حسب Lillia A. Baird (10575941)

"…Tofacitinib, an FDA-approved janus kinase (Jak) and signal transducer and activator (STAT) pathway inhibitor, reduces NK cytotoxicity and decreases overall levels in peripheral blood and may represent a potential ALS therapy. …"

Image 1_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff حسب Juliana R. Zampieri (22261441)

"…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.</p>Conclusion<p>While loss of p35 resulted in minor changes in phenotype, there were decreases in ARG-1 production and STAT3 phosphorylation, increased metabolism, and dramatically reduced antigen processing by M0, M1 or M2. …"

Data Sheet 3_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip حسب Haiyan Liao (6100043)

"…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"

Table 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.xlsx حسب Haiyan Liao (6100043)

"…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"

Table 2_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx حسب Lillia A. Baird (10575941)

"…Tofacitinib, an FDA-approved janus kinase (Jak) and signal transducer and activator (STAT) pathway inhibitor, reduces NK cytotoxicity and decreases overall levels in peripheral blood and may represent a potential ALS therapy. …"

Data Sheet 2_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip حسب Haiyan Liao (6100043)

"…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"

Image 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.tif حسب Haiyan Liao (6100043)

"…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"

Data Sheet 4_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip حسب Haiyan Liao (6100043)

"…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"

Image 3_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff حسب Juliana R. Zampieri (22261441)

"…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.</p>Conclusion<p>While loss of p35 resulted in minor changes in phenotype, there were decreases in ARG-1 production and STAT3 phosphorylation, increased metabolism, and dramatically reduced antigen processing by M0, M1 or M2. …"

Table 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx حسب Lillia A. Baird (10575941)

"…Tofacitinib, an FDA-approved janus kinase (Jak) and signal transducer and activator (STAT) pathway inhibitor, reduces NK cytotoxicity and decreases overall levels in peripheral blood and may represent a potential ALS therapy. …"

Data Sheet 5_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip حسب Haiyan Liao (6100043)

"…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …"

Data Sheet 1_Hyperbaric oxygen therapy for radiation enteritis and clinical parameters: a systematic review and meta-analysis.docx حسب Yuhan Wang (595964)

"…Moderate-quality evidence suggested that HBOT could significantly reduce the incidence of RE [OR = 0.32, 95% CI (0.14, 0.72), P = 0.006], particularly showing a significant advantage in decreasing the incidence of grade 3 or higher RE according to the RTOG/EORTC criteria [OR = 0.37, 95% CI (0.17, 0.82), P = 0.01]. …"

Table 2_Age-dependent diminution of female prognostic advantage in gastrointestinal stromal tumors: a retrospective cohort analysis.docx حسب Yue Zhang (30585)

"…Background<p>Sex and age are significant factors influencing the prognosis of various types of cancer. …"

Table 1_Age-dependent diminution of female prognostic advantage in gastrointestinal stromal tumors: a retrospective cohort analysis.docx حسب Yue Zhang (30585)

"…Background<p>Sex and age are significant factors influencing the prognosis of various types of cancer. …"

Effects of frequency difference, tactile conditions, and replicability. حسب Farzaneh Darki (22076051)

"…The proportion of trials in which the final (5th) triplet was reported as segregated increases with and increases (decreases) in Tact B (Tact AB) relative to Tact Off. …"

Image 2_Age-dependent diminution of female prognostic advantage in gastrointestinal stromal tumors: a retrospective cohort analysis.pdf حسب Yue Zhang (30585)

"…Background<p>Sex and age are significant factors influencing the prognosis of various types of cancer. …"

Image 1_Age-dependent diminution of female prognostic advantage in gastrointestinal stromal tumors: a retrospective cohort analysis.pdf حسب Yue Zhang (30585)

"…Background<p>Sex and age are significant factors influencing the prognosis of various types of cancer. …"

Image 1_Boys born with hypospadias and fetal growth restriction exhibit shorter anogenital distances: a retrospective cross-sectional study.tif حسب Wenfeng Pan (8726820)

"…Patients with hypospadias exhibited significantly shorter AGDs compared to the control group (P < 0.05). …"

Table 9_Transcriptome and metabolome profiling reveal the chlorogenic acid as a resistance substance for rice against the white-backed planthopper Sogatella furcifera (Horváth).xls... حسب Wenqi Xie (5903936)

"…Exogenous application of CGA to TN1 enhanced its tolerance and antixenosis to WBPH, significantly decreasing WBPH’s survival and mean dry weight. …"

Table 10_Transcriptome and metabolome profiling reveal the chlorogenic acid as a resistance substance for rice against the white-backed planthopper Sogatella furcifera (Horváth).xl... حسب Wenqi Xie (5903936)

"…Exogenous application of CGA to TN1 enhanced its tolerance and antixenosis to WBPH, significantly decreasing WBPH’s survival and mean dry weight. …"