Table_1_Diffusion and functional MRI reveal microstructural and network connectivity impairment in adult-onset neuronal intranuclear inclusion disease.docx by Rui Zhu (305217)

“…</p>Results<p>Compared with the HCs, NIID patients showed reduced mean kurtosis (MK), radial kurtosis (RK), axial kurtosis (AK), and kurtosis fractional anisotropy (KFA) values in deep gray matter regions. Significantly decreased MK, RK, AK, KFA and fractional anisotropy (FA), and increased mean diffusivity (MD) values were observed in extensive white matter fiber tracts. …”

Table 1_Minimally invasive versus open surgery in uterine serous carcinoma: impact on recurrence and survival in a multicenter cohort.xlsx by Yi Fang (287944)

“…Hypertension was also associated with decreased OS (HR = 2.06, 95% CI: 1.11–3.81, P = 0.022).…”

Supplementary Material for: Perioperative Blood Pressure Management Recommendations in Pediatric Pheochromocytoma: A 10-Year Narrative Review by Ambarsari C.G. (16518681)

“…Nevertheless, mortality rates decreased significantly in the latter half of the twentieth century due to effective perioperative blood pressure (BP) management. …”

Image 3_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg by Dang Li (16400478)

“…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …”

Supplementary file 1_Model-based multi-year P flow analyses and strategies for sustainable food chain management in Changzhou city at China's Taihu Basin.docx by Zheng Guo (14989)

“…Besides, urine diversion and waste incineration scenarios significantly decreased P accumulation in the food chain. …”

Image_2_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.jpg by Živa Frangež (5946392)

“…This reduction correlated with changes in the expression of autophagic activity markers, suggesting decreased basal levels of autophagy in primary and metastatic melanomas. …”

Table_1_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.docx by Živa Frangež (5946392)

“…This reduction correlated with changes in the expression of autophagic activity markers, suggesting decreased basal levels of autophagy in primary and metastatic melanomas. …”

Supplementary file 1_Burden of ageing spectrum of diseases in China, 1990–2021: a systematic analysis of global burden of disease study 2021.pdf by Li Yang (6520)

“…</p>Results<p>From 1990 to 2021, The ASR of all-cause DALYs in China decreased by 35.94% overall and by 33.99% among individuals ≥65 years. …”

Data Sheet 4_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

Data Sheet 1_Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells.pdf by Lizhan Su (19936980)

“…Mechanistically, LH treatment induced a rapid up-regulation of p38 MAPK signaling pathway in both infected and uninfected cells, which enhanced the expressions of NLRP3 and Caspase-1 proteins, thereby promoting the conversion of pro-IL-1β to IL-1β, which led to decreased PRRSV replication. In summary, this study reveals that early boosting of p38 MAPK signaling pathway induced by LH treatment significantly suppresses PRRSV propagation, and LH has the potential to be used as a novel antiviral agent against PRRSV infections.…”

Table 3_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf by Qiao Ma (136536)

“…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”

Data Sheet 1_The CaSBP11 gene functions as a negative regulator in pepper drought stress.doc by Huai-Xia Zhang (8493453)

“…Our results revealed that drought conditions significantly upregulated CaSBP11 expression, whereas ABA treatment suppressed it. …”

Health Risks of Low-Dose Dietary Exposure to Triphenyl Phosphate and Diphenyl Phosphate in Mice: Insights from the Gut–Liver Axis by Jing Cao (287196)

“…In DPHP-fed mice, serotonergic and glutamatergic synapses were simultaneously altered in the liver and intestine, corresponding to the reduction of five brain neurotransmitters (15.4–60.8%). Decreased liver carbohydrate levels and insulin resistance were observed in the DPHP-fed mice. …”

Image_3_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.JPEG by Katrina S. Hofstetter (17545425)

“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”

Image 1_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

Supplementary file 1_Transcriptional and neurotransmitter signatures of cerebral spontaneous neural activity in nurses with burnout.docx by Chun-Mei Song (21716903)

“…</p>Results<p>Nurses with burnout exhibited significantly decreased precuneus fALFF and reduced precuneus-right dorsolateral prefrontal cortex (DLPFC) FC compared to controls. …”

Supplementary Material for: Quality of Life After Alloplastic vs. Autologous Breast Reconstruction: 'The Influence of Patient Characteristics on Outcomes' by Holt-Kedde I.L. (20616542)

“…Conclusion: This study confirms that even when adjusted for confounders, scores on two QoL sub-scales autologous breast reconstruction patients score significantly higher over time. Although autologous reconstruction remained superior regarding “Satisfaction with Breasts”, scores decreased in autologous reconstruction patients when they were depressed at baseline, underwent radiotherapy, had a history of breast cancer, or faced major complications.…”

Outcomes of Corticosteroids Combined with 15 Mg/Week Methotrexate as Initial Treatment for Acute Vogt-Koyanagi-Harada Disease by Yao Lu (185912)

“…All the eyes had retinal reattachment and the choroidal thickness significantly decreased. Sun-set glow fundus was identified in 18 eyes (23.1%). …”

Table 1_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.docx by Jiayue Zhang (7832669)

“…</p>Results<p>The global all-age disability-adjusted life year (DALY) rate of ischemic stroke decreased by 34.90% between 1990 and 2021, with the highest disease burden in China, especially in males. …”

Image 7_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg by Dang Li (16400478)

“…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …”