Table 3_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx حسب Ying Dong (41989)

"…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. These genes were predominantly expressed in CD4⁺ T cells. …"

Image 1_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.tif حسب Linling Du (22827035)

"…During T cell differentiation, BTG2 expression initially increased, then decreased, followed by a subsequent rise in the mid-to-late stages; DERL3 expression exhibited a transient increase before returning to baseline; and FOS expression increased gradually throughout the process. …"

Utilization of lactate trajectory models for predicting acute kidney injury and mortality in patients with hyperlactatemia: insights across three independent cohorts حسب Yipeng Fang (14132676)

"…When compared with the Traj-3, Traj-2 was only significantly associated with the decreased risk of hospital mortality (OR 0.17, 95% CI 0.14–0.20, <i>p</i> < 0.001), but no with the likelihood of AKI development (OR 0.90, 95% CI 0.77–1.05, <i>p</i> = 0.172). …"

Image 2_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.tif حسب Yujuan Wu (2249857)

"…</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …"

Table 7_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx حسب Miguel Ângelo-Dias (20936444)

"…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"

Table 3_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... حسب Minseo Kim (773205)

"…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …"

Table 1_Communal and agentic teacher behavior in teacher-child dyads. A new self-report scale based on a circumplex approach.docx حسب Madeleine Kreutzmann (20296713)

"…Additionally, as child’s academic performance improved, teachers’ agency decreased. Towards different groups of children, teachers’ interpersonal behaviors varied systematically based on their professional beliefs: teachers with strong heterogeneity beliefs tended to be more communal towards low-performing children compared to high-performing children. …"

Image4_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

"…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …"

Image 5_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.tif حسب Linling Du (22827035)

"…During T cell differentiation, BTG2 expression initially increased, then decreased, followed by a subsequent rise in the mid-to-late stages; DERL3 expression exhibited a transient increase before returning to baseline; and FOS expression increased gradually throughout the process. …"

Image 3_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.tif حسب Linling Du (22827035)

"…During T cell differentiation, BTG2 expression initially increased, then decreased, followed by a subsequent rise in the mid-to-late stages; DERL3 expression exhibited a transient increase before returning to baseline; and FOS expression increased gradually throughout the process. …"

Image 2_Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.tif حسب Yiping Cao (1229856)

"…Pharmacological activation of local PVT A_2AR with its agonist CGS21680 induced significantly decreased 50% paw withdrawal threshold (50%PWTs) and paw withdrawal latency (PWLs), as measured by the Von Frey test and Hargreaves test in adult mice. …"

Data Sheet 5_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx حسب Liqin Liang (652560)

"…Conversely, silencing the ortholog gene NbSOS1-13 in Nicotiana benthamiana showed more accumulation of ROS, serious cell necrosis, reduced activities of SOD and CAT, significantly increased MDA level, obvious leaf wilting, decreased tolerance to infection, and reduced leaf stomatal closure rate and accelerated stomatal area. …"

Data Sheet 3_Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke.zip حسب Fengli Ye (22123540)

"…In vivo, FMT reduced hematoma volume and brain edema, improved neurological function, restored intestinal barrier proteins, decreased inflammatory cytokines, and downregulated hub gene expression.…"

Image 2_Inhibition of CRM1 reverses hypoxia-driven chemoresistance in acute myeloid leukemia via overcoming HIF-1α-mediated lysosomal sequestration.jpeg حسب Xiaohui Feng (2869535)

"…CRM1 and PHD2 expression increased under hypoxia, but nuclear accumulation of PHD2 decreased. Selinexor restored PHD2 nuclear localization, promoted HIF-1α degradation, reduced P-gp expression, and enhanced DNR nuclear accumulation. …"

Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts حسب Yu-Tse Lee (19944891)

"…In vivo studies showed that overall tumor metastasis decreased in 4T1 xenografts mice treated with MSN-PEG/TA 25 with a notable reduction in lung tumor metastasis. …"

Data Sheet 1_Spleen tyrosine kinase inhibition mitigates radiation-induced lung injury through anti-inflammatory effects and downregulation of p38 MAPK and p53.pdf حسب Guoxing Zhang (4994213)

"…The levels of TGF-β, COL1A1, and α-SMA and degree of pulmonary fibrosis at 10 weeks after radiation were also decreased by Syk inhibitor.</p>Conclusion<p>Syk inhibitor may have a potential to be used as a targeted drug to mitigate radiation pneumonitis and inhibit radiation-induced pulmonary fibrosis.…"

Table 2_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx حسب Miguel Ângelo-Dias (20936444)

"…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"

Table 1_Association between telomere length and idiopathic normal pressure hydrocephalus: a Mendelian randomization study.docx حسب Feng Yang (132135)

"…</p>Results<p>Genetically determined longer telomere length was significantly associated with decreased risk of iNPH (OR = 0.44, 95% CI 0.24–0.80; p = 0.008). …"

Data Sheet 1_Oral immunotherapy for cow’s milk allergy in children: a systematic review and meta-analysis.docx حسب Yan Wang (15435)

"…The meta-analysis indicated that oral immunotherapy significantly facilitated desensitization in patients with cow’s milk allergy in children (relative risk [RR] 2.51, 95% CI: 1.54–4.09, I²=84.4%). …"

Data Sheet 1_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.csv حسب Ying Dong (41989)

"…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. These genes were predominantly expressed in CD4⁺ T cells. …"