Image1_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG by Wen Zhou (49050)

“…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …”

Image 3_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff by José De Jesus Bravo-Silva (21898316)

“…In neonatal CD1 mice, melatonin markedly decreased viral loads in the brain and suppressed inflammatory gene expression, microglial activation, and M1/M2 polarization imbalance.…”

Image 8_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. These genes were predominantly expressed in CD4⁺ T cells. …”

Supplementary file 1_Dynamic changes in peripheral inflammation as a risk factor for perioperative sleep disturbances in elderly patients undergoing laparoscopic hepatobiliary surg... by Lai Wei (36699)

“…Findings indicated that elevated NLR and SII levels before and after surgery, alongside decreased plasma IL-10 levels post-surgery, are associated with a higher incidence of PSD. …”

Table 4_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx by Miguel Ângelo-Dias (20936444)

“…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”

Table 10_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx by Linling Du (22827035)

“…During T cell differentiation, BTG2 expression initially increased, then decreased, followed by a subsequent rise in the mid-to-late stages; DERL3 expression exhibited a transient increase before returning to baseline; and FOS expression increased gradually throughout the process. …”

Table 1_Dynamic changes in platelet counts and psychological state in ITP patients after COVID-19 infection.docx by Xiaoli Chen (102563)

“…The results showed that only in terms of low-grade fever, the proportion of ITP patients was significantly higher than that of healthy individuals, 31% vs. 17% (p = 0.04). …”

Image 4_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.tif by Linling Du (22827035)

“…During T cell differentiation, BTG2 expression initially increased, then decreased, followed by a subsequent rise in the mid-to-late stages; DERL3 expression exhibited a transient increase before returning to baseline; and FOS expression increased gradually throughout the process. …”

Data Sheet 1_Therapeutic potential of Cordyceps militaris cultivated with Ginkgo biloba seeds for alleviating western diet-induced type 2 diabetes and diabetic nephropathy.pdf by Shinn-Zong Lin (217003)

“…Key biochemical markers, including blood glucose, triglycerides, cholesterol, blood urea nitrogen (BUN), and creatinine, were significantly improved after treatment. Histopathologic analysis revealed restored renal morphology, reduced fibrosis and decreased amyloid deposition. …”

Data Sheet 1_Development of a rapid fiber-detection system using artificial intelligence in phase-contrast microscope images of actual atmospheric samples.pdf by Yukiko Iida (21596408)

“…Additionally, since the counting process relies on visual fiber counting, analytical accuracy can be decreased due to factors such as analyst fatigue. Ambient air samples or air samples collected near demolition sites were observed and acquired using a phase contrast microscope. …”

Image 2_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff by José De Jesus Bravo-Silva (21898316)

“…In neonatal CD1 mice, melatonin markedly decreased viral loads in the brain and suppressed inflammatory gene expression, microglial activation, and M1/M2 polarization imbalance.…”

Table 5_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx by Miguel Ângelo-Dias (20936444)

“…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”

Image 1_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a... by Linxi Qian (555385)

“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”

Table 2_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel... by Jingjian Dong (12458730)

“…In MH7A cells, PSPA decreased inflammatory cytokines (IL-1α, IL-6, IL-18), inhibited cell proliferation (IC50 = 1.43 μg/mL), and induced apoptosis by modulating Bcl-2, Bax, Caspase-3, and Caspase-9. …”

DataSheet1_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.docx by Xiang Li (114679)

“…Immunohistochemical analysis showed tofacitinib significantly decreased the pSTAT3 and pSTAT6 levels in the skin lesions of this patient. …”

Table 1_Association between DASH diet and metabolic syndrome in US adults: a cross-sectional study.xlsx by Jianing Liu (140090)

“…The proportion of women, younger individuals, non-Hispanic Blacks, low-income individuals, smokers, and those with MetS gradually decreased from Q1 to Q5 quintile groups. After adjusting for all variables, the odds ratio of MetS risk in the highest DASH quintile (Q5) compared with the lowest (Q1) was 0.60 (0.48, 0.77). …”

Shikonin promotes ferroptosis though NSUN2-mediated m⁵C methylation modification of TFRC in acute myelocytic leukemia by Shuyu Chen (4579207)

“…Overexpression of NSUN2 similarly decreased cell viability and increased cell death and ferroptosis, effects that were mitigated upon silencing of TFRC. …”

Table 3_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel... by Jingjian Dong (12458730)

“…In MH7A cells, PSPA decreased inflammatory cytokines (IL-1α, IL-6, IL-18), inhibited cell proliferation (IC50 = 1.43 μg/mL), and induced apoptosis by modulating Bcl-2, Bax, Caspase-3, and Caspase-9. …”

Supplementary Material for: Impact of Abemaciclib-induced Serum Creatinine Elevation on Dose Adjustment of Concomitant Medications by figshare admin karger (2628495)

“…Results: Of 221 patients included in this study, 30.8% had grade ≥2 Scr elevation at 1 month post-ABE initiation, increasing to 56.6% after 2 years. CCr significantly decreased after ABE initiation compared with that at baseline (median [interquartile range]: 44.5 [34.7–55.7] mL/min vs. 61.6 [49.3–81.1] mL/min, P < 0.01). …”

Table 1_Interaction between dietary selenium intake and age on severe headache or migraine in the United States: a population-based study.docx by Xinping Yu (555177)

“…</p>Conclusion<p>A higher dietary selenium intake is significantly associated with a decreased prevalence of migraine, and age can modify the association between them. …”