DataSheet1_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip حسب Jinxin Wang (1696837)

"…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …"

Image 1_Exercise intolerance in patients with chronic coronary syndrome: insights from exercise stress echocardiography.tiff حسب Wei-wei Zhu (20349897)

"…An elevated peak EDVi/E/e’ and a decreased ΔSVi are independent risk factors for exercise intolerance in patients with CCS.…"

Data Sheet 8_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... حسب Ying-han Deng (21604157)

"…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…"

Table 2_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Image 2_Exercise intolerance in patients with chronic coronary syndrome: insights from exercise stress echocardiography.tiff حسب Wei-wei Zhu (20349897)

"…An elevated peak EDVi/E/e’ and a decreased ΔSVi are independent risk factors for exercise intolerance in patients with CCS.…"

Data Sheet 2_Astragalus polysaccharide modulates the gut microbiota and metabolites of patients with major depressive disorder in an in vitro fermentation model: a pilot study.xlsx حسب Yuwei Mi (18003969)

"…APS fermentation increased the abundance of Bifidobacterium and decreased the abundance of Lachnoclostridium (p < 0.05). …"

DataSheet3_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip حسب Jinxin Wang (1696837)

"…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …"

<b>Patterns</b><b> and drivers of </b><b>plant C:N:P stoichiometry</b><b> across a 3000 km aridity gradient</b> حسب Jianzhao Wu (19185964)

"…Below this threshold (AI < 0.7), the leaf C:P and N:P ratios decreased as AI increased, and N limitation became more evident. …"

Supplementary file 6_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf حسب Yanling Wen (552195)

"…</p>Results<p>Our analysis revealed that the proportion of CCR7⁺ Tregs decreased as the disease advanced, while the cell proportion of HLA_DR⁺ regs escalated with the severity of the disease. …"

Supplementary file 1_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf حسب Yanling Wen (552195)

"…</p>Results<p>Our analysis revealed that the proportion of CCR7⁺ Tregs decreased as the disease advanced, while the cell proportion of HLA_DR⁺ regs escalated with the severity of the disease. …"

Data Sheet 1_Biorefinery—inspired, two-step valorization strategy to manage plant-based recalcitrant organic waste, involving solvent extraction, and fermentation with Bacillus cla... حسب Sreejith Meppoyilam (20563139)

"…This novel two-step valorization workflow involves the extraction of small molecules using organic solvents, and fermentation of resulting denatured residues (increased biodegradability or decreased recalcitrance) of reduced microbial load. …"

Image 1_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.tiff حسب Songtao Li (186776)

"…</p>Conclusion<p>These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.…"

Image2_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff حسب Alexandra Coello-Camba (6489533)

"…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …"

Alterations in gut microbiota and plasma metabolites in patients with generalized anxiety disorder: a multi-omics study حسب Yi Li (1144)

"…</p> <p>GAD was associated with increased abundances of <i>Actinobacteria</i>, <i>Bacteroidetes</i>, and <i>Escherichia-Shigella</i> and decreased abundances of <i>Firmicutes</i>, <i>Roseburia</i>, <i>Bifidobacterium</i>, and <i>Prevotellaceae_Prevotella</i>. …"

Table 3_Integrative physiological, biochemical, and metabolomic analyses reveal complex drought and zinc stress tolerance in a novel Miscanthus hybrid.xlsx حسب Monirul Islam (283000)

"…Fatty acid derivatives, nitrogen-containing compounds, hormone/signal-related compounds (jasmonate), and secondary metabolites (phenylpropanoids, N-containing compounds, and terpenes) showed significant (p < 0.05) abundance changes in response to D, Zn, and its combination D + Zn stress. …"

Table 2_High humidity environment increases FBG by impairing the intestinal barrier.docx حسب Yao Wang (102387)

"…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …"

Data Sheet 2_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... حسب Ying-han Deng (21604157)

"…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…"

Table 2_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.xlsx حسب Wenbing Zhang (152972)

"…A higher immune infiltration rate and lower IC50 values of anticancer drugs were significant in the high-risk group. In cellular experiments, Following MAN1B1 knockdown, in cell assays, the colony formation, migration, and invasion ability of HCT116 and HT29 cell lines decreased.…"

Image 2_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.tiff حسب Songtao Li (186776)

"…</p>Conclusion<p>These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.…"

Microbiome-host genetic association. حسب Tamizhini Loganathan (18538349)

"…Core microbiome and correlation analysis at the phylum and genus levels identified significant microbiota. Specifically, the abundance of genera such as <i>Pseudomonas</i> and <i>Akkermansia</i> decreased, while <i>Ruminococcus</i> and <i>Allistipes</i> increased, as determined by statistical and machine learning approaches. …"