Data Sheet 1_An exploratory study on the metagenomic and proteomic characterization of hypothyroidism in the first half of pregnancy and correlation with Th1/Th2 balance.docx حسب Chenchen Zhang (324804)

"…</p>Conclusion<p>Increased P. vulgatus and B. fragilis, decreased DGKK and S10A8 proteins, and a left shift in the Th1/Th2 balance in patients with hypothyroidism in the first half of pregnancy may be associated with the development of the disease.…"

The role of IRF-1 in mediating T-cell immune imbalance in systemic lupus erythematosus and the construction of a diagnostic model حسب Zichen Huang (6587885)

"…Immune analysis revealed decreased numbers of resting CD4⁺ memory T cells and Tregs (<i>P</i> < 0.01), alongside expanded proinflammatory cells (M1/M2 macrophages, neutrophils; <i>P</i> < 0.01). …"

Location map of the study area. حسب Chao Ma (207385)

"…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …"

Multifaceted roles of NADPH oxidases in the growth and pathogenicity of <i>Beauveria bassiana</i> حسب Shengan Zhu (19817727)

"…Deletion of BbNoxB or BbNoxR decreased fungal virulence compared to the WT strain in topical inoculation experiments. …"

Table 2_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.docx حسب Songtao Li (186776)

"…</p>Conclusion<p>These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.…"

Table 1_Association between oral health status and frailty in older adults: a systematic review and meta-analysis.docx حسب Jingwen Huang (232382)

"…Investigating the relationship between oral health and frailty in older adults is of significant importance for preventing frailty, ensuring the quality of life for older adults, and promoting healthy longevity.…"

Table 5_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Table 8_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Aetiology, clinical characteristics, and risk factors influencing mortality in patients with infective endocarditis: a retrospective study حسب Özkan Vural (21470515)

"…Despite advancements in diagnosis and treatment, incidence and mortality rates have not decreased. In this study, we evaluated the clinical and laboratory parameters of patients with infective endocarditis followed in our hospital between 2005 and 2018 and assessed their relationship with in-hospital and one-year mortality.…"

Image5_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff حسب Alexandra Coello-Camba (6489533)

"…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …"

Data source. حسب Chao Ma (207385)

"…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …"

Data Sheet 1_Thalamic functional dysconnectivity in patients with left-hemisphere chronic capsular and pontine stroke.pdf حسب Jun Guo (85069)

"…</p>Results<p>The ipsilesional thalamus of CS patients had abnormally decreased FC with widespread cognitive-related areas while increased FC with visual- and somatic-motor areas. …"

Table 1_A two-sample bidirectional Mendelian randomization analysis between telomere length and hyperthyroidism.xlsx حسب Shiben Zhu (19159465)

"…The risk of hyperthyroidism decreased as genetically predicted TL increased by one standard deviation, as determined by the IVW form GWAS Catalog (OR:0.659,95%CI: 0.541-0.802, p <0.001) and IVW from FinnGen(OR:0.634, 95%CI: 0.479-0.840, p = 0.001). …"

Image 1_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.tif حسب Wenbing Zhang (152972)

"…A higher immune infiltration rate and lower IC50 values of anticancer drugs were significant in the high-risk group. In cellular experiments, Following MAN1B1 knockdown, in cell assays, the colony formation, migration, and invasion ability of HCT116 and HT29 cell lines decreased.…"

Image 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o... حسب Yangtian Jiao (21725018)

"…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …"

Table 1_Inequalities and age-period-cohort effects of global and regional burden for interstitial lung disease and pulmonary sarcoidosis: based on Global Burden of Disease study 20... حسب Lei Zhang (38117)

"…Background<p>Interstitial lung disease (ILD) and pulmonary sarcoidosis pose significant disease burdens on a global scale.</p>Methods<p>The underlying data was derived from the Global Burden of Disease (GBD) 2021 database. …"

DataSheet5_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf حسب Yongming Du (807059)

"…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…"

Research Technology Flow Chart. حسب Chao Ma (207385)

"…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …"

Image1_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff حسب Alexandra Coello-Camba (6489533)

"…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …"

Presentation1_Pressure-tolerant survival mechanism of Schizophyllum commune 20R-7-F01 isolated from deep sediments 2 kilometers below the seafloor.pdf حسب Mengshi Zhao (20157978)

"…By assessing the cell viability, biomass, and cell wall thickness changes of strain 20-7-1 under different HHP conditions, we observed that, compared to 0.1 MPa, strain 20-7-1 exhibited slower growth rates and decreased cell viability at 15 MPa and 35 MPa, yet demonstrated significant pressure tolerance. …"