Data Sheet 8_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx حسب Shengyou Song (22391068)

"…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…"

Image 1_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.jpeg حسب Jiashuo Li (7865036)

"…Immunohistochemistry showed that HRG expression was decreased in HCC compared to normal tissues, whereas TUBA1B expression was elevated in HCC.…"

Data Sheet 1_New prognostic features and personalized treatment strategies of mitochondrial related genes in colorectal cancer patients.docx حسب Qizheng Xu (21077153)

"…Key mitochondrial genes, including SUCLG2, ACACB, OSBPL1A, and TRAP1, have been identified as significant prognostic markers in CRC. The expression of ACACB and OSBPL1A progressively increased, while SUCLG2 and TRAP1 expression decreased in patients. …"

Table 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx حسب Thibaud Dauphin (21196820)

"…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …"

Table 1_Evaluating treatment and care outcomes for neuromuscular diseases in a pediatric intermediate care setting.docx حسب Giacomo Brisca (10963929)

"…The majority of admissions were due to neurological issues (39.7%) and respiratory complications (22%), with a significant proportion of patients requiring initiation or potentiation of respiratory support (59%). …"

Data Sheet 1_PM2.5 exposure reprograms cell cycle dynamics in uterine immune cells at single-cell resolution.docx حسب Lin Zhang (8926)

"…Notably, we observed significant changes in immune cell populations, including reductions in macrophages (510 to 58 cells), NK cells (445 to 91 cells), and granulocytes (1597 to 1 cells). …"

DataSheet2_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf حسب Yongming Du (807059)

"…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…"

Image 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.pdf حسب Maxim Sorokin (4379848)

"…We detected no statistically significant difference in the number of chimeric transcripts in FFPE and FF RNAseq profiles. …"

Workflow of the study. حسب Hongliang Chen (538815)

"…Experiments revealed that the expression of the ACADM and ACADSB genes was decreased in UC patients. Mitochondrial dysfunction contributes to the pathogenesis of UC by altering energy metabolism, promoting immune disorders and activating pathogenic signaling pathways. …"

DataSheet8_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.zip حسب Yongming Du (807059)

"…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…"

Table 5_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x... حسب Yuan Li (67017)

"…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …"

Image 2_Nusinersen for children with type I spinal muscular atrophy: 4 years’ clinical experience in Turkish cohort.jpeg حسب Ömer Bektaş (13827139)

"…Ventilator and gastrostomy requirements decreased in the early treated cohorts. Adverse events were rare, with one discontinuation due to hydrocephalus. …"

Data Sheet 1_hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways.doc حسب Yan Yu (56143)

"…Background<p>Breast cancer remains a leading cause of mortality among women worldwide, with existing therapeutic options often accompanied by significant side effects and a persistent risk of disease recurrence. …"

Effect of miR-7974 mimic transfection on proliferation of MDA-MB-453 cells together with changes in protein and gene expression levels of LC3B. حسب Stralina Eneh (21213312)

"…<b>(B)</b> The fold change of total protein levels of LC3B between negative control/cells only samples and miR-7974-treated samples were statistically significant. <b>(C)</b> The gene expression levels of <i>LC3B</i> were decreased 72h after miR-7974 transfection of MBA-MB-453 cells compared to the negative control/cells-only samples. …"

Table 4_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x... حسب Yuan Li (67017)

"…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …"

Table 2_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x... حسب Yuan Li (67017)

"…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …"

Table 1_Nusinersen for children with type I spinal muscular atrophy: 4 years’ clinical experience in Turkish cohort.docx حسب Ömer Bektaş (13827139)

"…Ventilator and gastrostomy requirements decreased in the early treated cohorts. Adverse events were rare, with one discontinuation due to hydrocephalus. …"

Data Sheet 1_Impact of a structured food sequence and mobile health monitoring on gestational diabetes outcomes: a clinical trial.pdf حسب Ria Murugesan (21795620)

"…A p-value <0.05 was considered statistically significant.</p>Results<p>The intervention group showed significant reductions in 1-h and 2-h postprandial blood glucose levels (−8.41 mg/dL and −7.56 mg/dL respectively, both p < 0.001), decreased LDL cholesterol (−7.33 mg/dL, p < 0.001), increased HDL cholesterol (+6.15 mg/dL, p < 0.001), and improved hemoglobin levels. …"

Image 1_Nusinersen for children with type I spinal muscular atrophy: 4 years’ clinical experience in Turkish cohort.jpeg حسب Ömer Bektaş (13827139)

"…Ventilator and gastrostomy requirements decreased in the early treated cohorts. Adverse events were rare, with one discontinuation due to hydrocephalus. …"

Table 7_Nusinersen for children with type I spinal muscular atrophy: 4 years’ clinical experience in Turkish cohort.docx حسب Ömer Bektaş (13827139)

"…Ventilator and gastrostomy requirements decreased in the early treated cohorts. Adverse events were rare, with one discontinuation due to hydrocephalus. …"