Repetitive stress induces a reduction in sound-evoked activity that develops as the stressor becomes chronic. by Ghattas Bisharat (20706928)

“…We found a negative slope in most cells especially for mid-intensities, indicating a decrease in activity as the stress becomes chronic (<i>t</i> test for 40 dB <i>p</i> = 0.36, for 60 dB <i>p</i> = 9.3 × 10⁻¹², and for 70 dB <i>p</i> = 0.00750). …”

DataSheet1_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.DOCX by Na Wang (193263)

“…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …”

Table 2_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx by Ivan Antipenko (22808513)

“…In the syncytiotrophoblast (SCT), the primary maternal-fetal barrier, preeclampsia was associated with a significant downregulation of LDLR and cholesterol biosynthesis genes (OR = 4.991, p = 6.30e−04). …”

Table 1_Global burden of tuberculosis attributable to diet low in whole grains from 1990 to 2021, with projection to 2045.pdf by Xiaoning Lu (206322)

“…</p>Results<p>In 2021, TB-DLWG accounted for 177,303.55 DALYs globally, representing an 8% decrease from 1990. The number of deaths was 5,539.13, a 12% reduction. …”

Image_1_Education and metabolic syndrome: a Mendelian randomization study.pdf by Dong Liu (115204)

“…</p>Conclusion<p>The findings of this study suggest that education can decrease the incidence of MetS.</p>…”

Supplementary file 1_Characteristics, clinical evidence and implementation effects of conditional approvals for drugs in China, a pooled analysis from 2020 to 2023.docx by Li Yang (6520)

“…The efficacy evidence of CAs supported by single-arm trials demonstrated statistically significant variances in indication and drug types. …”

Video 1_Progressive encephalomyelitis with rigidity and myoclonus after thymectomy in a woman with myasthenia gravis.mp4 by Lixia Qin (3358520)

“…The patient was treated with intravenous methylprednisolone, oral clonazepam, and tacrolimus, which resulted in significant clinical improvement. A 2-year follow-up demonstrated sustained recovery, accompanied by a decrease in GAD65 antibody titers. …”

Table 1_Evaluation of clopidogrel responsiveness using the Platelet Function Analyzer-200 (PFA-200) in dogs.docx by Joon-Ho Shin (2161726)

“…Among the assessed parameters, only D-dimer levels showed a significant decrease in the clopidogrel-responder group (p < 0.05), suggesting its potential utility in evaluating responsiveness. …”

Image 1_Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.tiff by Junxian Hu (8158044)

“…In this study, we observed that under low hydrostatic pressure, TRPV4 activation and subsequent calcium influx led to an increase in CRT synthesis and a significant rise in its cytosolic expression. This was followed by the depolymerization of focal adhesion (FA) complexes, primarily consisting of FAK and integrin β1, which resulted in an increase in collagen type II (Col II) and a decrease in collagen type I (Col I). …”

DataSheet2_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.DOCX by Na Wang (193263)

“…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …”

Supplementary file 1_Active fungal infections alter the respiratory microbiome profiles of Mayo Clinic Arizona patients.zip by Daniel R. Kollath (18134608)

“…Patients with disseminated coccidioidomycosis showed evidence of extreme dysbiosis in the lung microbiome with a significant overabundance of Malassezia and Bacilli. …”

Image 1_Multi-omics analysis reveals neutrophil heterogeneity and key molecular drivers in sepsis-associated acute kidney injury.jpg by Tianle Cheng (20788417)

“…We identified four neutrophil subtypes—pro-inflammatory, anti-inflammatory, mature, and immature—revealing a significant increase in pro-inflammatory neutrophils in sepsis (40.53% versus 4.19% in controls) and a decrease in anti-inflammatory neutrophils (18.43% versus 27.04%). …”

Table 2_The comparison of remimazolam and midazolam in bronchoscopic sedation: a systematic review and meta-analysis of randomized controlled trials.docx by Yahya Kayed AbuJwaid (21676193)

“…</p>Conclusion<p>Remimazolam may reduce induction and recovery times and decrease the need for rescue sedation compared to midazolam. …”

EXP-DDQN algorithm framework. by Sen Cao (6017846)

“…Furthermore, EXP-DDQN demonstrates significant improvements over traditional DQN and DDQN methods across these metrics. …”

Genetic variants in mitochondrial sirtuins associated with brain tumor risk: a case–control study by Maria Fazal Ul Haq (14659737)

“…Kaplan–Meier analysis showed that mutant allele frequency was found to be associated with a significant decrease in the survival of brain tumor patients.…”

Healthy control group HR and CBF changes. by Liuchuang Wei (19273099)

“…<div><p>Postural Orthostatic Tachycardia Syndrome is characterized by an excessive increase in heart rate during postural changes without significant blood pressure alterations, often accompanied by symptoms such as dizziness, fatigue, and palpitations. …”

Image 2_Multi-omics analysis reveals neutrophil heterogeneity and key molecular drivers in sepsis-associated acute kidney injury.jpg by Tianle Cheng (20788417)

“…We identified four neutrophil subtypes—pro-inflammatory, anti-inflammatory, mature, and immature—revealing a significant increase in pro-inflammatory neutrophils in sepsis (40.53% versus 4.19% in controls) and a decrease in anti-inflammatory neutrophils (18.43% versus 27.04%). …”

Table 3_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.csv by Ivan Antipenko (22808513)

“…In the syncytiotrophoblast (SCT), the primary maternal-fetal barrier, preeclampsia was associated with a significant downregulation of LDLR and cholesterol biosynthesis genes (OR = 4.991, p = 6.30e−04). …”

Supplementary Material for: The effect of far infrared treatment on changes in biomarkers in the arteriovenous fistula by figshare admin karger (2628495)

“…Regardless of treatment group, four-hours of HD caused a significant decrease in tumor necrosis factor-alpha (-1.30 [-1.70;-1.03] pg/ml , P= <0.001), monocyte chemoattractant protein-1 (-32.50 [-50.50;-8.25] pg/ml, P= <0.001), nitrite, and nitrate (-20.00 [-27.75;-14.00] µmol/L, P= <0.001) as well as asymmetric dimethylarginine(-0.24 [-0.28;-0.18], µmol/L P= <0.001). …”

Table 1_The comparison of remimazolam and midazolam in bronchoscopic sedation: a systematic review and meta-analysis of randomized controlled trials.docx by Yahya Kayed AbuJwaid (21676193)

“…</p>Conclusion<p>Remimazolam may reduce induction and recovery times and decrease the need for rescue sedation compared to midazolam. …”