Supplementary Material for: Feedback from human instructors is superior to guidance by a virtual reality simulator when learning flexible bronchoscopy – a randomized controlled tri... حسب figshare admin karger (2628495)

"…[Results] All three groups showed an improvement in SP, DC, PT and NASA-TLX during their 12 procedures (P<.05), without a decrease in performance three weeks later (P>0.05). …"

Table 5_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx حسب Chengli Yu (1445185)

"…Early detection and removal of precancerous lesions during the adenoma-carcinoma sequence can significantly reduce CRC risk. However, current clinical practice lacks rapid, noninvasive screening tools for reliable adenoma detection.…"

Ganaxolone: A Review in Epileptic Seizures Associated with Cyclin‑Dependent Kinase‑Like 5 Deficiency Disorder حسب Sheridan M. Hoy (4897468)

"…In a multinational phase III study (Marigold), 17 weeks’ therapy with adjunctive ganaxolone, administered orally three times daily with food, significantly reduced 28-day major motor seizure frequency from baseline versus placebo in patients aged 2–19 years with CDD-associated refractory epilepsy. …"

Image 1_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.png حسب Giulia Santarelli (14246638)

"…We observed a slight decrease in the microbial burden following LcM247 administration, while treatment with CFS significantly reduced microbial growth compared to control and antimicrobial compounds. …"

Data Sheet 1_Isoform-specific vs. pan-histone deacetylase inhibition as approaches for countering glioblastoma: an in vitro study.docx حسب Ameya Joshi (1290186)

"…The non-specific inhibitor Vorinostat surprisingly promoted migration in the cells at its 2D IC50 value treatment, and none of the inhibitors was able to significantly decrease late resistance compared to untreated controls, indicating the need for the development of more potent HDAC inhibitors for monotherapy for GBM.…"

JAK/STAT signaling can activate MMP expression. حسب Bente Winkler (20760273)

"…In pupal stages, <i>Mmp2</i> expression decreases significantly upon <i>STAT92E</i> downregulation and reaches control levels. …"

Comparative Internal and External AUC Performance Across Single-Site Models. حسب Ioana Duta (18462981)

"…At Agincourt, the internal AUC is 0.96 (interquartile range (IQR) 0.95–0.97), while the external AUC is 0.88 (IQR 0.86–0.88), demonstrating a statistically significant difference with a decrease of approximately 0.08 in performance when models are externally validated. …"

Supplementary Material for: A Randomized Controlled Crossover Trial to Determine the Effects of Three Nostril Regulated Breathing Practices on Attention and Mood حسب figshare admin karger (2628495)

"…A significant main effect of states was observed followed by significant post-hoc pair wise comparison in right NDR for (i) pleasant mood after SAV, CAV, AV and QS, (ii) positive mood after SAV and AV, and (iii) global vigor after SAV, CAV, AV and QS, and (iv) a decrease in negative mood after CAV and AV. …"

Association of lactate-albumin ratio with native liver survival in paediatric acute liver failure: a 10-year retrospective study حسب Zhen Zhang (86004)

"…</p> <p>Among 77 patients, 46.8% (36 cases) had SNL, with 14.3% (11 cases) requiring transplantation. A significant decrease in SNL was associated with higher LAR (<i>p</i> = 0.005), with a 4% decline in SNL for each 1% increase in LAR. …"

DataSheet1_Association between changes in thyroid hormones and incident type 2 diabetes using joint models of longitudinal and time-to-event data: more than a decade follow up in t... حسب Alireza Amirabadizadeh (6399635)

"…Background<p>Type 2 diabetes mellitus (T2DM) poses a significant public health challenge, contributing to considerable morbidity and mortality worldwide, which necessitates urgent preventive measures. …"

Data Sheet 1_N6-methyladenosine RNA landscape in the aged mouse hearts.zip حسب Xia Jing (3255219)

"…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H₂O₂-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …"

Data Sheet 2_N6-methyladenosine RNA landscape in the aged mouse hearts.zip حسب Xia Jing (3255219)

"…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H₂O₂-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …"

Data Sheet 3_N6-methyladenosine RNA landscape in the aged mouse hearts.zip حسب Xia Jing (3255219)

"…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H₂O₂-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …"

Data Sheet 4_N6-methyladenosine RNA landscape in the aged mouse hearts.pdf حسب Xia Jing (3255219)

"…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H₂O₂-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …"

Image 1_Epimedium brevicornu Maxim. extract activates natural killer cells against hepatocellular carcinoma via the cGAS-STING pathway.tif حسب Lu Liu (171341)

"…., a traditional Chinese botanical drug, has shown significant therapeutic effects against hepatocellular carcinoma (HCC), with its flavonoid compounds exhibiting anti-HCC activity through various mechanisms. …"

Data_Sheet_2_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.PDF حسب Meng Chen (48769)

"…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …"

Data_Sheet_1_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.PDF حسب Meng Chen (48769)

"…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …"

Table_1_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.DOCX حسب Meng Chen (48769)

"…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …"

Table 2_Serum uric acid/creatinine ratio and 1-year stroke recurrence in patient with acute ischemic stroke and abnormal renal function: results from the Xi'an stroke registry stud... حسب Zhongzhong Liu (111119)

"…Compared to Q1, the Q2 and Q4 groups showed significantly reduced risk in 1-year stroke recurrence (Q2: HR = 0.46, 95% CI 0.27 to 0.79, P = 0.005; Q4: HR = 0.47, 95% CI 0.27 to 0.81, P = 0.007), with a significant trend across all quartiles (P = 0.01 for trend tests). …"

Table 1_Serum uric acid/creatinine ratio and 1-year stroke recurrence in patient with acute ischemic stroke and abnormal renal function: results from the Xi'an stroke registry stud... حسب Zhongzhong Liu (111119)

"…Compared to Q1, the Q2 and Q4 groups showed significantly reduced risk in 1-year stroke recurrence (Q2: HR = 0.46, 95% CI 0.27 to 0.79, P = 0.005; Q4: HR = 0.47, 95% CI 0.27 to 0.81, P = 0.007), with a significant trend across all quartiles (P = 0.01 for trend tests). …"