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significantly enhance » significantly enhanced (Expand Search), significantly influenced (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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21121
Table 3_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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21122
H2AK119ub is neurodevelopmentally enriched within H3K9ac-positive euchromatin.
Published 2025“…(F) Heatmaps depicting H3K9ac CUT&RUN data within loci with no change, increased or decreased H2AK119ub over neurodevelopment. (G) Heatmaps depicting H3K9ac CUT&RUN data within loci harboring both H2AK119ub and H3K27me3. …”
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21123
Table1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.docx
Published 2024“…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…”
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21124
Image2_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg
Published 2024“…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…”
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21125
Image3_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg
Published 2024“…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…”
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21126
Image1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg
Published 2024“…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…”
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21127
Time-limited downregulation of cerebellar neurophysiological processes in NHPs during LACV infection.
Published 2025“…The color scale is based on the significance (-log<sub>10</sub> p-adj). The gene ontology (GO) sources: BP, Biological Process; CC, Cellular Component; and MF, Molecular Function (terms are highlighted by respective colors). …”
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21128
Risk of bias across 22 included studie.
Published 2024“…</p><p>Results</p><p>A meta-analysis of 22 RCTs (n = 3,463) showed that ketamine/esketamine significantly decreased PPD risk at 1- (risk ratio [RR], 0.41; 95% confidence interval [CI], 0.3–0.57) and 4–6-week (RR, 0.47; 95%CI, 0.35–0.63) follow-ups. …”
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21129
Table 1_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx
Published 2025“…Compared with control interventions, acupuncture significantly reduced VAS scores, decreased the frequency and duration of migraine attacks, and improved response rates, as well as HIT-6 and MHI scores. …”
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21130
Table 1_Avoiding touching until 60 min—contamination of transdermal estradiol gel after physical contact.docx
Published 2025“…In the estradiol gel group, estradiol levels remained stable within the first 30 min (p >0.05), rapidly decreased at 60 min (p <0.001) and remained stable from 60 min to 120 min (p >0.05). …”
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21131
Figure 2 from Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in <i>EGFR</i>- and <i>KRAS</i>-Mutant Lung Cancer
Published 2025“…<p>PRMT1 knockdown decreases persistence in STAT1-high <i>EGFR</i><sup><i>mut</i></sup> and <i>KRAS</i><sup><i>G12C</i></sup> lung cancer cell lines. …”
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21132
Table 2_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx
Published 2025“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
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21133
Supplementary data: Characterization of medical device randomized controlled trials with adaptive designs
Published 2024“…The average annual number of adaptive RCTs per 1000 clinical trials was the highest (8.55 ± 11.65) during 2005–2010, reduced to 3.33 ± 2.35 during 2011–2016, and significantly decreased to 1.29 ± 0.85 during 2017–2024 (p = 0.011). …”
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21134
Image 3_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.tiff
Published 2025“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
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21135
Image 4_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif
Published 2025“…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …”
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21136
Table 1_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx
Published 2024“…Association analysis showed that all six SNPs were significantly associated with milk protein percentage. …”
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21137
Image 4_Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker—epicardial adipose tissue mass index: a...
Published 2025“…Background<p>Although reperfusion therapy has led to improvements in the acute phase of ST-segment elevation myocardial infarction (STEMI), the incidence of major adverse cardiovascular events (MACE) following STEMI has not significantly decreased. The accumulation of epicardial adipose tissue (EAT) may be associated with poorer STEMI prognosis and could serve as a potential prognostic marker. …”
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21138
Image 4_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co...
Published 2025“…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …”
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21139
Table 6_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx
Published 2024“…Association analysis showed that all six SNPs were significantly associated with milk protein percentage. …”
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21140
Table 1_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx
Published 2025“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”