The T-type voltage-gated Ca²⁺ channel Ca_V3.1 involves in the disruption of respiratory epithelial barrier induced by <i>Pasteurella multocida</i> toxin by Haixin Bi (6867632)

“…This was evidenced by a decreased expression of tight junctions (ZO-1, occludin) and adherens junctions (β-catenin, E-cadherin), as well as enhanced cytoskeletal rearrangement. …”

DataSheet1_Dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model.docx by Yuhan Zhang (2792089)

“…Retinal levels of inflammatory factors were significantly decreased in Ala-Gln-treated diabetic rats. …”

Data Sheet 3_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

Supplementary file 3_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg by Yuhui Zhang (399617)

“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”

Supplementary file 4_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx by Yuhui Zhang (399617)

“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”

Image 9_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg by Jie Li (15030)

“…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O₂⁻ production rate. …”

Table 1_Angiotensin converting enzyme inhibitors and angiotensin receptor blockers impact on the gut microbiome: a systematic review.docx by Elisabeth M. Wang (22480771)

“…In the human study, ACEi/ARB use did not significantly alter microbial diversity, but decreased populations of facultative aerobic pathogens including Staphylococcus and Enterobacterales. …”

Image 8_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg by Jie Li (15030)

“…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O₂⁻ production rate. …”

CO₂fertilisation counteracts the negative effect of poor water quality on the growth and photosynthesis of a Great Barrier Reef coralline alga_datasheets by Bonnie Lewis (20407157)

“…We found complex interactions between factors on algal growth and photosynthetic rates, but overall, growth was significantly enhanced by <i>p</i>CO₂ enrichment under all light and nutrient combinations. …”

Data Sheet 1_Deglycosylated azithromycin alleviates cisplatin-evoked constipation in mice by altering host metabolome and gut microbiota composition.docx by Xiaoting Gu (3368495)

“…</p>Results<p>Deg-AZM significantly enhanced intestinal motility in the mice with cisplatin-evoked constipation. …”

Data Sheet 1_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

Table 1_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx by Lin Liu (74495)

“…AKK also modulated the expression of metabolites linked to neuroinflammation and cognitive function, upregulated BDNF and TrkB, and decreased IBA1, suggesting it enhances cognitive function by modulating neuroinflammation and the BDNF/TrkB signaling pathway.…”

Data Sheet 1_Anti-colorectal cancer effect of total minor ginsenosides produced by lactobacilli transformation of major ginsenosides by inducing apoptosis and regulating gut microb... by Yunjiao Shen (20524133)

“…</p>Results<p>In vitro studies demonstrated that TMG significantly inhibited proliferation and promoted apoptosis in CT26.WT cells. …”

Supplementary file 1_Petroselinum sativum (Parsley) extract suppresses oxidative stress and inflammatory responses in human keratinocytes and reduces atopic dermatitis symptoms in... by Juan Wang (115708)

“…The results showed that HE extracts of parsley (HEP) contained the highest TPC and TFC and exhibited the strongest antioxidant activity, significantly improving cell viability and reducing ROS levels in t-BHP-treated cells. …”

Table 1_The CD300c antibody CL7 suppresses tumor growth by regulating the tumor microenvironment in non-small cell lung carcinoma.docx by Soyoung Kim (117362)

“…CL7 treatment also modulated the tumor microenvironment by increasing the population of M1 macrophages and CD8⁺ T cells, while decreasing the population of regulatory T cells. Our findings suggest that CL7 exerts antitumor effects in NSCLC by reprogramming the immunosuppressive landscape of the TME and enhancing antitumor immunity.…”

Table 1_Efficacy and safety of acupuncture for postoperative gastroparesis syndrome: a systematic review and meta-analysis.docx by Yichuan Xv (18702754)

“…The meta-analysis showed a significantly higher overall response rate in the acupuncture group than the control group [RD = 0.16, 95% CI (0.11, 0.21), p < 0.001]. …”

Data Sheet 2_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.pdf by Yonghu Chen (2040136)

“…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”

Data Sheet 1_Influence of water temperature on feed intake, appetite control, and energy allocation in Atlantic salmon (Salmo salar) post-smolt.pdf by F. Lai (17234491)

“…Plasma ghrelin (Ghrl) levels decreased significantly at elevated temperature. Temperature negatively affected the ghrl1 expression in the stomach, and the expression dynamics of the orexigenic neuropeptide npya and anorexigenic pomca paralogues in the hypothalamus, which were lower at 15°C. …”

<b>SZC-6</b><b> Promotes Diabetic Wound Healing in Mice by Modulating M1/M2 Macrophage Ratio and Inhibiting MyD88/NF-κB Pathway</b> by 昂 轩 (20139579)

“…We also found that SZC-6 significantly reduced MyD88, p-IκBα, and p-P65 protein levels and inhibited the nuclear translocation of P65 in LPS-treated cells. …”

Supplementary file 1_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg by Yuhui Zhang (399617)

“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”