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significantly enhanced » significantly influenced (Expand Search), significantly reduced (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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20481
RNA quality photo
Published 2025“…Moreover, although the expression of the GRP78 gene increased in the sinus tissue of diabetic patients with mucormycosis, it significantly decreased in the same patients after treatment. …”
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20482
Presentation 1_CRIF1 gene therapy ameliorates inflammatory bowel disease by suppressing TH17 cells and fibrosis through mitochondrial function regulation.zip
Published 2025“…Patients with ulcerative colitis exhibited decreased CRIF1 levels with dysfunctional mitochondria in inflamed colonic tissue. …”
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20483
Supplementary Material for: Global, regional, and national burden of motor neuron disease: a systematic analysis of prevalence, incidence, deaths, and DALYs with projections to 203...
Published 2025“…Results: From 1990 to 2021, the global number of MND cases, deaths, and DALYs increased significantly, while the age - standardized prevalence and incidence rates decreased. …”
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20484
Image 6_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.jpeg
Published 2025“…Purpose<p>Diabetic cardiomyopathy (DCM), which is diabetes mellitus-induced cardiomyopathy, significantly elevates the risk of heart failure and sudden cardiac death. …”
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20485
Table 2_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf
Published 2025“…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”
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20486
Point Application Therapy Targeting Feishu, Pishu and Shenshu Attenuates Asthma by Suppressing Autophagy and the AMPK-mTOR Signalling Pathway
Published 2025“…The treatment additionally decreased expression levels of mTOR, LC3, NF-κB and TGF-β1 while increasing AMPK content. …”
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20487
Kalman process.
Published 2025“…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…”
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20488
Image 3_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg
Published 2025“…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”
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20489
Data Sheet 1_Early coronary angiography in patients with myocardial infarction without ST elevation after out-of-hospital cardiac arrest: a systematic review and meta-analysis.pdf
Published 2024“…Observational study subgroup showed decreased short-term mortality, long-term mortality, and CPC 1–2 at discharge, unlike RCT subgroup. …”
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20490
Supplementary file 1_Bioactive fraction isolated from Curcuma angustifolia rhizome exerts anti-diabetic effects in vitro, in silico and in vivo by regulating AMPK/PKA signaling pat...
Published 2025“…After 28 days of intervention, the lower and higher doses of the bioactive fraction (100 and 200 mg/kg BW) substantially decreased fasting blood glucose levels and ameliorated hyperglycemia, glucose intolerance, insulin resistance, and hyperlipidemia. …”
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20491
Data Sheet 1_Total flavonoids isolated from Eucommia ulmoides can alleviate bone loss and regulate intestinal microbiota in ovariectomized rats.docx
Published 2025“…</p>Results<p>Oral administration of TFEL for 13 weeks increased the serum level of bone formation marker PINP and decreased the level of bone resorption marker NTX-I. …”
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20492
Data Sheet 1_Polydopamine nanoparticles as immunomodulators: inhibition of M1 microglial polarization.docx
Published 2025“…To mimic neuroinflammatory conditions, HMC3 cells were stimulated with interferon-gamma (IFN-γ), which significantly increased intracellular ROS levels, surface expression of CD40 and CD86, and secretion of pro-inflammatory cytokines. …”
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20493
Image_1_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg
Published 2024“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”
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20494
Attention mechanism.
Published 2025“…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…”
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20495
Table 1_Co-frequency or contrary? The effects of Qiwei Baizhu Powder and its bioactive compounds on mucosa-associated microbiota of mice with antibiotic-associated diarrhea.docx
Published 2024“…The results showed that QWBZP-TG significantly altered the diversity, structure, and abundance of MAM in the AAD mice. …”
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20496
Table 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx
Published 2025“…</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …”
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20497
Data Sheet 2_CqHKT1 and CqSOS1 mediate genotype-dependent Na+ exclusion under high salinity conditions in quinoa.pdf
Published 2025“…By contrast, K<sup>+</sup> accumulation was slightly reduced in the aerial parts but significantly decreased in the roots of all the genotypes. …”
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20498
Presentation 1_Ischemia-reperfusion injury with a model of porcine whole-blood ex-vivo lung perfusion.pptx
Published 2025“…Interleukin-6 and −8 levels after 6 h were significantly higher in the long CIT group (mean differences, 1.1 pg/ml; 95% CI, 0.39–1.8; P = 0.003; and 29.31 pg/ml; 95%CI, 16.00–42.61; P < 0.001; respectively). …”
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20499
Image 1_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg
Published 2025“…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”
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20500
Image 2_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif
Published 2025“…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …”