Force chain network After shear loading. by Hui Cheng (195456)

“…The results indicate significant geographical heterogeneity in loess strength indices, with the structural properties of loess being a primary factor contributing to this variability. …”

Force chain network Before shear loading. by Hui Cheng (195456)

“…The results indicate significant geographical heterogeneity in loess strength indices, with the structural properties of loess being a primary factor contributing to this variability. …”

Particle distribution of soil sample composition. by Hui Cheng (195456)

“…The results indicate significant geographical heterogeneity in loess strength indices, with the structural properties of loess being a primary factor contributing to this variability. …”

Image2_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.tif by Wenchao Tang (14710556)

“…</p>Results<p>Following CTD exposure, the mouse liver showed significant pathological damage and an increase in autophagic lysosomes, while the vitality of L-O2 cells showed a significant decrease. …”

Table1_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.pdf by Wenchao Tang (14710556)

“…</p>Results<p>Following CTD exposure, the mouse liver showed significant pathological damage and an increase in autophagic lysosomes, while the vitality of L-O2 cells showed a significant decrease. …”

Image1_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.png by Wenchao Tang (14710556)

“…</p>Results<p>Following CTD exposure, the mouse liver showed significant pathological damage and an increase in autophagic lysosomes, while the vitality of L-O2 cells showed a significant decrease. …”

Table 1_Association between estimated glucose disposal rate and the risk of atherosclerotic cardiovascular disease: insight from cross-sectional and retrospective cohort studies.do... by Zixuan Wang (35190)

“…</p>Conclusion<p>This study elucidates the significant negative dose-response linear relationship of eGDR with ASCVD risk and the partial mediation effects of AIP, VAI, CMI, LAP, and BMI, highlighting the significance of enhancing glucose-utilizing capacity in decreasing the risk of ASCVD.…”

Telomere-to-telomere genome of <i>Phoebe chekiangensis</i> reveals age-dependent CHG hypomethylation promoting floral transition via MADS-box gene activation by Qinglin Sun (17811556)

“…Their ectopic expression in Arabidopsis significantly accelerated flowering. Whole-genome bisulfite sequencing revealed an age-related decrease in CHG methylation, particularly at the PcMADS19.1 locus. …”

Table 1_Molecular hybridization modification improves the stability and immunomodulatory activity of TP5 peptide.docx by Junyong Wang (3807964)

“…The half-life of YTP in plasma is significantly longer than that of YW12D and TP5. YTP also displays an improved ability to protect the host from CTX-induced weight loss and thymus and spleen indices decrease than YW12D and TP5. …”

Microbial Alliances: Unveiling the Effects of a Bacterial and Fungal Cross-Kingdom SynCom on Bacterial Dynamics, Rhizosphere Metabolites, and Soybean Resilience in Acidic Soils by Zhongling Wen (13878743)

“…Metagenomics and metabolomics revealed that RhRi significantly enhanced beneficial microorganisms (<i>AD3, Gemmataceae</i>) and metabolites (putrescine, stearic acid), hence improving nutrient cycling, stress tolerance, and membrane integrity. …”

Data Sheet 1_Safety and immunomodulatory efficacy of heat-killed Mycolicibacterium manresensis as a novel paraprobiotic in swine.pdf by Carmen Álvarez-Delgado (18964264)

“…Piglets supplemented with higher doses of hkMm exhibited a significant increase in salivary adenosine deaminase levels (p = 0.0042), along with a significant decrease in serum haptoglobin concentration (p = 0.0263). …”

Data Sheet 1_Altered mitochondrial mass and low mitochondrial membrane potential of immune cells in patients with HBV infection and correlation with liver inflammation.pdf by Liling Ma (16752684)

“…In CHB patients with normal ALT but liver inflammation detected on B-scan ultrasonography, a significant decrease was observed in the MMP^low percentage of CD8⁺T (66.13 ± 14.27), CD56⁺NK(57.77 ± 17.40) and CD4^-CD8^-T (61.98 ± 15.98) cells. …”

DataSheet1_Feasibility exploration of GSH in the treatment of acute hepatic encephalopathy from the aspects of pharmacokinetics, pharmacodynamics, and mechanism.DOCX by Kangrui Hu (18718429)

“…Pharmacokinetic studies suggested that AHE modeling led to significant decrease in hepatic and cerebral exposure of GSH and cysteine. …”

Table 1_The impact of public participatory environmental regulation on carbon emission intensity: a policy text analysis.docx by Jianzu Wu (13935369)

“…The findings reveal that: (1) public participatory environmental regulation significantly reduces carbon emission intensity; specifically, baseline regression results indicate that a one-unit increase in public participatory environmental regulation intensity leads to a 0.05 unit decrease in carbon emission intensity, significant at the 1% level; (2) mediation analysis demonstrates that public environmental participation serves as a significant intermediary between environmental regulation and carbon emission reduction; (3) heterogeneity analysis indicates that official characteristics significantly moderate policy effectiveness, with regulations implemented by non-local, shorter-tenured, and less-educated officials showing stronger inhibitory effects on carbon emissions compared to their counterparts. …”

Image 1_Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.tiff by Junxian Hu (8158044)

“…In this study, we observed that under low hydrostatic pressure, TRPV4 activation and subsequent calcium influx led to an increase in CRT synthesis and a significant rise in its cytosolic expression. This was followed by the depolymerization of focal adhesion (FA) complexes, primarily consisting of FAK and integrin β1, which resulted in an increase in collagen type II (Col II) and a decrease in collagen type I (Col I). …”

Data Sheet 1_Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.zip by Junxian Hu (8158044)

“…In this study, we observed that under low hydrostatic pressure, TRPV4 activation and subsequent calcium influx led to an increase in CRT synthesis and a significant rise in its cytosolic expression. This was followed by the depolymerization of focal adhesion (FA) complexes, primarily consisting of FAK and integrin β1, which resulted in an increase in collagen type II (Col II) and a decrease in collagen type I (Col I). …”

Table 1_Efgartigimod combined with steroids as a fast-acting therapy for anti-SRP immune-mediated necrotizing myopathy.doc by Qiqi Peng (6560057)

“…Evidently, these three patients demonstrated significant improvement in muscle strength and decrease of serum CK levels after efgartigimod treatment. …”

DataSheet1_Chronic exposure to inhaled vaporized cannabis high in THC suppresses Adderall-induced brain activity.zip by Jack M. Ognibene (19830132)

“…After a 2-week wash out there were no significant differences between the cannabis and placebo groups when challenged with Adderall.…”

Effect of different light conditions on the growth response of sugar beet to NaCl by Ryota Obama (20179531)

“…Because it is known that glycine betaine activates antioxidant enzyme activities and reduces oxidative stress responses, glycine betaine synthesized in response to NaCl accumulation may have reduced the oxidative stress caused by high light intensity in the shoots, which may have caused the enhanced growth in sugar beet. Furthermore, the growth promotion by NaCl accumulation was accompanied by a significant decrease in NO₃–N concentration, which suggested that NaCl application affects nitrogen metabolism in sugar beet.…”

Image_2_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.tif by Sofia Priyadarsani Das (17830028)

“…The diet containing L. acidophilus at 1 × 10⁷ CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. Moreover, it upregulated several physiological pathways such as carbohydrate metabolism, signal transduction, lipid metabolism, nucleotide metabolism, amino acid metabolism, and environmental adaptation, which led to the upregulation of the AMPK, MAPK, P13K-Akt, lysosome, peroxisome, and ferroptosis signaling pathways; this enhanced growth and immunity in white shrimp. …”