Supplementary file 1_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.docx by Hai-Qing Tan (22173514)

“…., high-income North America: EAPC = −1.07, 95% CI: −1.82–−0.32), whereas industrializing regions showed significant increases (e.g., East Asia: EAPC = 2.01, 95% CI: 1.02–3.19). …”

Table 4_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.xlsx by Xiaofeng Li (342614)

“…</p>Conclusion<p>We elucidated the significant impact of crotonylation on the ovarian cancer microenvironment and prognosis. …”

Image 4_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.tif by Xiaofeng Li (342614)

“…</p>Conclusion<p>We elucidated the significant impact of crotonylation on the ovarian cancer microenvironment and prognosis. …”

Table 6_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.csv by Xiaofeng Li (342614)

“…</p>Conclusion<p>We elucidated the significant impact of crotonylation on the ovarian cancer microenvironment and prognosis. …”

Data Sheet 6_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv by Ke-Jie He (13239966)

“…Background<p>Particulate matter (PM) pollution is a significant risk factor for ischemic heart disease (IHD). …”

Table 1_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.xlsx by Xiaofeng Li (342614)

“…</p>Conclusion<p>We elucidated the significant impact of crotonylation on the ovarian cancer microenvironment and prognosis. …”

Data Sheet 4_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip by Hai-Qing Tan (22173514)

“…., high-income North America: EAPC = −1.07, 95% CI: −1.82–−0.32), whereas industrializing regions showed significant increases (e.g., East Asia: EAPC = 2.01, 95% CI: 1.02–3.19). …”

Data Sheet 1_Effects of chili straw on rumen fermentation, meat quality, amino acid and fatty acid contents, and rumen bacteria diversity in sheep.docx by Jinlong Li (388896)

“…Key findings include: (1) No significant differences were observed in rumen pH, NH₃-N, or acetic acid-to-propionic acid ratio across groups (P > 0.05). (2) Rumen microbial diversity indices did not vary significantly between groups (P > 0.05), though the relative abundance of Firmicutes and Proteobacteria increased, and Bacteroidota decreased in CS-fed groups, with specific genus-level changes. (3) Carcass weight decreased in the CS20% group (P < 0.01). (4) Cooking loss decreased in CS10%, 15%, and 20% groups (P < 0.05), and meat redness increased in CS15% and 20% groups (P < 0.01). (5) Saturated fatty acids decreased, while the PUFA/SFA ratio and amino acid profiles, including sulfur-containing amino acids (SAA), dibasic amino acids (DAA), essential amino acids (EAA), and total amino acids (TAA), increased with CS, with a significant rise in Gly content in the CS15% group (P < 0.05). …”

Table1_Response of photosynthesis, population physiological indexes, and yield of cotton in dry areas to the new technology of “dry sowing and wet emergence”.docx by Yu Ding (54012)

“…The appropriate "DSWE" irrigation technology (W3D2) can significantly enhance the physiological indicators of cotton, ensuring crop yield and quality while significantly reducing the amount of agricultural irrigation water.…”

Da-Yuan-Yin decoction suppresses NETs formation, inhibits the IL-23/JAK2/STAT3 signalling pathway, and modulates metabolic profiles and gut microbiota composition in damp-heat synd... by Yun Yang (417125)

“…Furthermore, it modulated inflammatory responses, suppressed the interleukin-23 (IL-23)/janus kinase-2 (JAK2)/signal transduction and transcription activator-3 (STAT3) signaling pathway and enhanced antioxidant activity. DYY administration significantly increased total SCFA content. …”

Supplementary file 1_The impact of enterprise digital transformation on employees’ intrinsic motivation: the mediating role of justice perceptions.docx by Xiaorui Chang (22804850)

“…The research results, derived from path analysis and moderating effect analysis methods, indicate that enterprise digital transformation has an motivational effect on employees’ intrinsic motivation, and employees’ distributive justice, procedural justice, and interactional justice perceptions all play significant mediating roles, while information processing job characteristics show significantly different moderating effects on different motivational paths: When information processing are low, the distributive justice path loses its motivational effect, while the motivational effect of the interactional justice path significantly decreases when information processing are high, and the moderating effect on the procedural justice path is always insignificant. …”

Table 1_Preventive administration of shengmaiyin: a novel approach to counteract heatstroke-induced coagulopathy in rats.xlsx by Longping He (18492915)

“…The EHS group showed significantly prolonged PT and APTT, increased Lac, decreased platelet count, and elevated plasma levels of TM, vWF, TSP-1, and PAI-1 compared to the NC group (P < 0.05). …”

Identification of a Novel Virulence Factor in <i>Klebsiella pneumoniae</i> through CpxR-Dependent Transcriptional Activation by Runze Wang (21792959)

“…Among the genes exhibiting significantly decreased expression upon <i>cpxR</i> deletion<i>, </i>we identified a novel potential virulence factor KPHS_28080. …”

Supplementary Material for: Adjuvant Lip Gauze Wet Dressing Restores Lip Barrier Function and Improves Atopic Cheilitis by figshare admin karger (2628495)

“…Results indicated that patients exhibited decreased lip barrier function, which improved significantly with gauze wet dressing, enhancing hydration and normalizing pH levels within 30 minutes. …”

Effects of contralateral noise on CAEP (Lee et al., 2025) by Donguk Lee (21628297)

“…The presentation of contralateral noise had a significant effect on P1 and N1 latencies, both of which decreased. …”

DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF by Huan Yu (140826)

“…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”

Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx by Mingming Xie (20963636)

“…Additionally, the paw withdrawal mechanical threshold in BCP mice increased, while the number of spontaneous foot lifts decreased. In complementary cellular studies, transfection-mediated overexpression of MrgC in N2a cells enhanced UPR^mt biomarker expression, whereas RNA interference-mediated MrgC knockdown produced the opposite effect.…”

Table 1_Gypenoside XLIX inhibiting PI3K/AKT/FOXO1 signaling pathway mediated neuronal mitochondrial autophagy to improve patients with ischemic stroke.docx by Yonglei Liu (5485793)

“…</p>Results<p>Gypenoside XLIX significantly improved neuronal viability (p < 0.01), reduced apoptosis (p < 0.01), and decreased ROS levels (p < 0.001) in OGD cells. …”

Table 1_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx by Yue Bu (11357379)

“…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”

Table 2_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx by Yue Bu (11357379)

“…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”