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3521
Data Sheet 1_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.zip
Published 2025“…Background and Objectives<p>Multiple sclerosis (MS) significantly impacts adolescents and young adults (aged 15–39 years), causing substantial neurological disability. …”
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3522
Data Sheet 2_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.docx
Published 2025“…Background and Objectives<p>Multiple sclerosis (MS) significantly impacts adolescents and young adults (aged 15–39 years), causing substantial neurological disability. …”
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3523
Table 3_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.docx
Published 2025“…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”
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3524
Table 1_Effects of compound probiotics on growth performance, immunity, antioxidant capacity and gut microbiota in weaned rabbits.docx
Published 2025“…</p>Results and discussion<p>Our results showed that dietary supplementation with probiotic significantly promoted growth performance (e.g., increased average daily gain and decreased feed-to-gain ratio), enhanced immune function (reflected by elevated plasmic immunoglobulin levels and reduced pro-inflammatory cytokine concentrations) and improved antioxidant capacity (manifested by higher activities of superoxide dismutase and glutathione peroxidase and lower malondialdehyde content) in weaned rabbits. …”
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3525
Data Sheet 1_Physical activity of moderate-intensity optimizes myocardial citrate cycle in a murine model of heart failure.pdf
Published 2025“…Interestingly, 8-sWR significantly decreased myocardial citrate content in the presence of unchanged myocardial [BCAAs], ETC proteins content and mtDNA copy number.…”
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3526
DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF
Published 2024“…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”
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3527
Table 1_Efficacy and safety of dietary polyphenol supplements for COPD: a systematic review and meta-analysis.docx
Published 2025“…As bioactive compounds exhibiting dual antioxidant and anti-inflammatory properties, polyphenolic derivatives demonstrate significant therapeutic potential through multimodal mechanisms targeting COPD pathophysiology - particularly in modulating redox homeostasis (GSH/GSSG ratio elevation), attenuating NF-κB-mediated inflammatory cascades, and enhancing respiratory function parameters (FEV1 improvement ≥12% from baseline). …”
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3528
Data Sheet 1_Efficacy and safety of dietary polyphenol supplements for COPD: a systematic review and meta-analysis.zip
Published 2025“…As bioactive compounds exhibiting dual antioxidant and anti-inflammatory properties, polyphenolic derivatives demonstrate significant therapeutic potential through multimodal mechanisms targeting COPD pathophysiology - particularly in modulating redox homeostasis (GSH/GSSG ratio elevation), attenuating NF-κB-mediated inflammatory cascades, and enhancing respiratory function parameters (FEV1 improvement ≥12% from baseline). …”
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3529
Video (Efficacy of uterine manipulator in total abdominal hysterectomy)
Published 2025“…No significant differences were observed in postoperative complications or pain scores between groups. …”
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3530
Table 1_High-dose thiamine supplementation ameliorates obesity induced by a high-fat and high-fructose diet in mice by reshaping gut microbiota.xlsx
Published 2025“…</p>Results<p>The results showed that high-dose thiamine supplementation for eight weeks could significantly alleviate symptoms of HFFD-induced obesity and improve HFFD-induced intestinal epithelial barrier dysfunction by enhancing the tight junction function. …”
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3531
Image 1_High-dose thiamine supplementation ameliorates obesity induced by a high-fat and high-fructose diet in mice by reshaping gut microbiota.tif
Published 2025“…</p>Results<p>The results showed that high-dose thiamine supplementation for eight weeks could significantly alleviate symptoms of HFFD-induced obesity and improve HFFD-induced intestinal epithelial barrier dysfunction by enhancing the tight junction function. …”
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3532
Image 1_Effect of hypoxia-induced mIL15 expression on expansion and memory progenitor stem-like TILs in vitro.tif
Published 2024“…RNA-Seq data revealed that in TIL-mIL15-IL2 cells, the expression of genes related to T cell differentiation and effector function, including PRDM1, ID2, EOMES, IFNG, GZMB, and TNF, were significantly decreased, whereas the expression of the memory stem-like T cell marker TCF7 was significantly increased. …”
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3533
Table 1_A study on the effects of modified sprint interval trainingon physical fitness test scores and the quantitative and dose-response relationships among Chinese male universit...
Published 2025“…</p>Results<p>The results showed significant improvements in key anaerobic capacity indicators after the 6-week intervention: Average Power (AP) increased from 77.4 ± 10.1 to 132.6 ± 21.1 (p < 0.01, Adjusted p < 0.03 ment, with a maximum effect size of 3.344), Peak Power (PP) increased from 102.9 ± 14.5 to 189.5 ± 28.8 (p < 0.01, Adjusted p < 0.02, maximum effect 3.790), and Time to Peak Power (TTP) decreased from 12.3 ± 3.3 to 9.5 ± 2.6 (p < 0.01), confirming that the intervention enhanced the participants' anaerobic capacity. …”
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3534
Data Sheet 1_hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways.doc
Published 2025“…Background<p>Breast cancer remains a leading cause of mortality among women worldwide, with existing therapeutic options often accompanied by significant side effects and a persistent risk of disease recurrence. …”
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3535
Data Sheet 1_Global, regional, and national burden of interstitial lung disease in middle-aged and older adults from 1990 to 2021 with projections to 2050: a systematic analysis of...
Published 2025“…Joinpoint regression analysis revealed that while ASPR and ASIR increased from 1990 to 2010 but subsequently decreased from 2010 to 2021, conversely, ASDR and DALYs increased from 1990 to 2011 before declining after 2011, frontier analysis highlighted Canada, Ireland, the United States, Japan, and the United Kingdom as nations with significant improvement potential. …”
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3536
Data Sheet 1_Water accessibility as a catalyst for food diversity: a case study.pdf
Published 2025“…A decreasing trend of FCS and DDS with an increase in the time needed to fetch water indicated a significant negative correlation (Spearman's correlation analyzing all participants = −0.178, p < 0.001 and −0.221, p < 0.001, respectively). …”
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3537
Table 1_Water accessibility as a catalyst for food diversity: a case study.pdf
Published 2025“…A decreasing trend of FCS and DDS with an increase in the time needed to fetch water indicated a significant negative correlation (Spearman's correlation analyzing all participants = −0.178, p < 0.001 and −0.221, p < 0.001, respectively). …”
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3538
Image 1_Water accessibility as a catalyst for food diversity: a case study.pdf
Published 2025“…A decreasing trend of FCS and DDS with an increase in the time needed to fetch water indicated a significant negative correlation (Spearman's correlation analyzing all participants = −0.178, p < 0.001 and −0.221, p < 0.001, respectively). …”
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3539
Long-term changes in macronutrients, micronutrients, and potentially toxic elements under 33 years of continuous chemical fertilizer and organic matter application
Published 2025“…The content of macronutrient elements (Ca, Mg, P, and K) remained stable with organic matter added treatments, with Ca and P significantly correlating with C and N (<i>p</i> < 0.05). …”
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3540
Table1_Slow-release boron fertilizer improves yield and nutritional profile of Beta vulgaris L. grown in Northeast China by increasing boron supply capacity.docx
Published 2024“…Boron fertilizer can increase soil B content and significantly improve crop yield and quality. At present, the effects of slow-release B fertilizer on beet root yield and quality remain unclear. …”