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4301
Dexmedetomidine improves septic acute kidney injury by inhibiting inflammation and oxidative stress through the activation of the Pink1/Park2 autophagy pathway
Published 2025“…Notably, all results were statistically significant. Overall, our findings revealed that dexmedetomidine may mitigate inflammation, oxidative stress, and renal dysfunction in mice with SAKI by upregulating the Pink1/Park2-mediated autophagy pathway. …”
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4302
Image 2_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o...
Published 2025“…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …”
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4303
Data Sheet 1_Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells.docx
Published 2025“…Flow cytometry revealed that HU-308 restored the Th17/Treg imbalance in AIA, decreasing Th17 cell frequency and enhancing Treg cell infiltration. …”
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4304
Table 4_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
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4305
Data Sheet 1_The protective effects and mechanisms of rosmarinic acid against Pseudomonas aeruginosa infection in Caenorhabditis elegans.doc
Published 2025“…Introduction<p>Pseudomonas aeruginosa poses a significant risk to both the environment and organisms. …”
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4306
The Effect of Confinement on the Phase Behavior of <i>n</i>‑Pentane in Nanoporous Media: An Experimental Investigation at Varying Pore Sizes and Temperatures
Published 2025“…<i>n</i>-Pentane, a key component of crude oil and gas condensate, exhibits altered phase behavior under nanoconfinement, affecting enhanced oil recovery (EOR) and hydrocarbon production in shale reservoirs. …”
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4307
Data Sheet 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Bur...
Published 2025“…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …”
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4308
Table 1_High humidity environment increases FBG by impairing the intestinal barrier.xlsx
Published 2025“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”
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4309
Table 1_The impact of environmental and health messaging, pulse prevalence, and filtering tools on pulse-based food choice and nutrient profiles: a randomized online experiment.doc...
Published 2025“…</p>Results<p>Results showed that messaging alone and increasing the prevalence of pulse products had modest but significant impacts [range of adjusted odds ratios (95% confidence intervals): 1.35 (1.00, 1.83) to 2.91 (2.26, 3.75)]. …”
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4310
Table 1_Intergenerational education mobility in India: nonlinearity and the Great Gatsby Curve.docx
Published 2024“…</p>Results<p>Our analysis reveals a high degree of intergenerational persistence in education, although this persistence has decreased over time. Employing quantile regressions, we observe significant nonlinearities in the relationship between fathers’ and sons’ educational outcomes across the educational distribution. …”
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4311
<b>Social conditions alter the growth, metabolic rate, behavioral traits, and food-shelter preferences in the qingbo </b><b><i>Spinibarbus sinensis</i></b>
Published 2024“…These findings suggest that visual social isolation may not be a significant stressor for qingbo, as the isolation-reared qingbo exhibited improved growth. …”
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4312
Table 2_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
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4313
Data Sheet 2_Astragalus polysaccharide modulates the gut microbiota and metabolites of patients with major depressive disorder in an in vitro fermentation model: a pilot study.xlsx
Published 2025“…APS fermentation increased the abundance of Bifidobacterium and decreased the abundance of Lachnoclostridium (p < 0.05). …”
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4314
Table 2_High humidity environment increases FBG by impairing the intestinal barrier.docx
Published 2025“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”
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4315
Table 1_Singing for memory: neural and cognitive effects of a choral intervention in older adults.docx
Published 2025“…Additionally, task-dependent functional connectivity increased between the right lateral prefrontal cortex, left posterior fusiform cortex and left hippocampus, while connectivity between the right lateral prefrontal cortex and the left inferior frontal gyrus decreased after the intervention.</p>Discussion<p>These findings suggest that regular participation in choral singing may enhance episodic memory and have a positive influence on related brain networks in older adults. …”
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4316
Table 3_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
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4317
Table 1_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
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4318
Table 3_High humidity environment increases FBG by impairing the intestinal barrier.xlsx
Published 2025“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”
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4319
Sex-specific responses of mosquitoes to <i>Bti</i> pesticide and odonate predators
Published 2025“…We found that Bti reduced larval abundance by ~90% within 48 hours but did not induce an overcompensatory response in adult production or fitness. Predators had no significant effect on larvae within 48 hours, but they did have sex-specific effects on the abundance and size of adult mosquitoes. …”
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4320
Table 6_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”