Data Sheet 1_α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT–FOXO1–CD36 pathway.pdf by Xue Bai (129175)

“…</p>Results<p>In HG/F-induced H9C2 cells, A-MG (1 and 3 μM) significantly increased cell viability (p < 0.01) and reduced LDH release (p < 0.05). …”

Data Sheet 1_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

Data Sheet 2_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

Data Sheet 1_Perceived benefits and barriers to the use of long-acting injectable antiretroviral treatment among adolescents and young people living with HIV in Western Kenya: qual... by Shukri A. Hassan (14245301)

“…Participants viewed LA ART as a welcome alternative to oral ART due to benefits like improved adherence, reduced pill burden, increased convenience, enhanced privacy, decreased stigma, lower risk of accidental disclosure, and convergence in using LA contraception. …”

Data Sheet 2_Perceived benefits and barriers to the use of long-acting injectable antiretroviral treatment among adolescents and young people living with HIV in Western Kenya: qual... by Shukri A. Hassan (14245301)

“…Participants viewed LA ART as a welcome alternative to oral ART due to benefits like improved adherence, reduced pill burden, increased convenience, enhanced privacy, decreased stigma, lower risk of accidental disclosure, and convergence in using LA contraception. …”

Table 1_Evaluating the Implementation of fan-beam CT-guided online adaptive re-planning in definitive cervical cancer radiotherapy.docx by Shuai Sun (775057)

“…This approach has shown significant improvements in dose distribution and the potential to provide clinical benefits by reducing acute toxicity.…”

Table 1_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”

Table 4_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”

Image 1_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.tif by Ning An (618997)

“…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”

Table 3_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”

Table 2_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Metabolic risks, particularly high systolic blood pressure, were significant contributors to HHD-related mortality and DALYs, with a pronounced impact in high-SDI regions. …”

Assessing the Causal Role of Walking Pace and Hand Grip Strength with Chronic Obstructive Pulmonary Disease Hospital: A Mendelian Randomization Study by Lu Wang (45927)

“…</p> <p>Our research shows a link between slower walking pace and higher COPD hospitalization risk, as well as decreased lung function (PEF, FEV1, FVC). We also found a significant correlation between weaker hand grip and reduced lung function, especially FVC. …”

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” by Chanping You (9067448)

“…TRIM37 overexpression decreased palbociclib sensitivity, while its knockdown enhanced sensitivity and attenuated the effect of AR on RB1 levels and drug response, establishing TRIM37 as a novel E3 ligase that bound RB1 via its MATH and C-terminal domains.…”

DataSheet1_The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner.docx by Mehri Hajiaghayi (19822665)

“…Nebivolol-treated β₂-knockout memory Th cells showed significant inhibition of β₂-AR-mediated signaling, evidenced by the absence of IL-17A suppression compared to controls. …”

TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts by Thuc Ly (12832686)

“…Autophagy in CAFs is constitutive and independent of STAT3, MAPK1/ERK2-MAPK3/ERK1 and phosphoinositide 3-kinase (PI3K) signaling. Despite the significant role of secretory autophagy in CAFs, its molecular machinery has remained elusive. …”

KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity by Mengyu Liu (2890397)

“…Further analysis indicated significant impairment of autophagic flux by TMT via suppressed lysosomal function, such as by inhibiting lysosomal proteolysis and changing the lysosomal pH, thereby contributing to defects in autophagic clearance and subsequently leading to nerve cell death. …”

<b>Dielectric Properties of Composite PZT Films with Distinct Phase Transition Temperatures via Aerosol Deposition</b> by Ye-Ji Son (20656475)

“…As shown in <b>Figure 6(b)</b>, annealing significantly enhanced the dielectric properties of the composite PZT film. …”

Table 1_Organic and inorganic fertilizers modulate the response of the soil microbiome to salinity stress.docx by Halima Malal (21570602)

“…Furthermore, NPK fertilization increased bacterial network complexity but decreased its stability. This study underscores the significance of employing vermicompost to improve the health of saline soils. …”

Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing by Noora Kantola (14263490)

“…Our results show that grazing may enhance ecosystem stability to winter climate change in comparison to long-term absence of grazing. …”

Age-related driver injury occurrence from crashes at curve–grade combined segments by Hellen Shita (19746166)

“…</p> <p>The results emphasize the significance of tailored education and outreach countermeasures, particularly for teen and older drivers, aimed at decreasing the likelihood of injuries in such driving environments. …”