Search alternatives:
significantly enriched » significantly enhanced (Expand Search), significantly increased (Expand Search), significantly decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
enriched decrease » enrichment decreases (Expand Search)
significantly enriched » significantly enhanced (Expand Search), significantly increased (Expand Search), significantly decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
enriched decrease » enrichment decreases (Expand Search)
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4041
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4042
Cohort Evidence Links Phthalate Exposure to Early Onset of Puberty in Chinese Girls
Published 2025Subjects: -
4043
Mean interval from initial diagnosis to initiation of non-pharmacological treatment by year.
Published 2025Subjects: “…treatment initiation decreased…”
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4044
General information of patient who diagnosis insomnia disorder (N = 518,119).
Published 2025Subjects: “…treatment initiation decreased…”
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4045
Detailed treatment status of people who received non- pharmacological treatment at first diagnosis.
Published 2025Subjects: “…treatment initiation decreased…”
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4046
Treatment at first diagnosis of insomnia disorder (%).
Published 2025Subjects: “…treatment initiation decreased…”
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4047
ERI Thresholds Between Adjacent Zones.
Published 2025“…The transition and desert zones decreased by 49.7% and 37.9%, respectively. The ERI decreased and was strongly correlated with the OLS. …”
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4048
Location of the study area.
Published 2025“…The transition and desert zones decreased by 49.7% and 37.9%, respectively. The ERI decreased and was strongly correlated with the OLS. …”
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4049
Random Forest structure with cross-validation.
Published 2025“…The transition and desert zones decreased by 49.7% and 37.9%, respectively. The ERI decreased and was strongly correlated with the OLS. …”
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4050
Land use change from 1990 to 2020.
Published 2025“…The transition and desert zones decreased by 49.7% and 37.9%, respectively. The ERI decreased and was strongly correlated with the OLS. …”
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4051
Geographic data.
Published 2025“…The transition and desert zones decreased by 49.7% and 37.9%, respectively. The ERI decreased and was strongly correlated with the OLS. …”
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4052
Classification accuracy.
Published 2025“…The transition and desert zones decreased by 49.7% and 37.9%, respectively. The ERI decreased and was strongly correlated with the OLS. …”
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4053
Vps34 supports Treg maintenance in lymphoid and non-lymphoid tissues.
Published 2025“…(<b>E</b>) CD4<sup>+ </sup>Foxp3-YFP<sup>+</sup> Tregs (CD45.2<sup>+</sup>) were sort-purified from the spleen of control (<i>n</i> = 4) or <i>Foxp3</i><sup>Cre</sup><i>Pik3c3</i><sup>fl/fl</sup> (<i>n</i> = 5) mixed BM chimera mice and profiled by microarray analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#sec010" target="_blank">Materials and methods</a> for details). GSEA enrichment plots showing increased cTreg signature (left; i.e., top 200 upregulated genes [log<sub>2</sub>FC > 0.5, FDR < 0.05] in cTregs versus eTregs) and decreased eTreg signature (right; i.e., top 200 upregulated genes [log<sub>2</sub>FC > 0.5, FDR < 0.05] in eTregs versus cTregs) in CD45.2<sup>+</sup> Tregs from <i>Foxp3</i><sup>Cre</sup><i>Pik3c3</i><sup>fl/fl</sup> mixed BM chimera mice compared to control mixed BM chimera mice. …”
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4054
Vps34 orchestrates transcriptional and epigenetic remodeling events corresponding to terminal eTreg differentiation during perinatal life.
Published 2025“…GSEA, gene set enrichment analysis; NES, normalized enrichment score; FDR, false discovery rate. …”
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4055
Chromatin accessibility analysis of perinatal Vps34-deficient Tregs.
Published 2025“…(<b>B</b>) Quantification of relative (normalized to average control in each experiment) gMFIs of CellROX and MitoSOX in TCRβ<sup>+</sup>CD4<sup>+ </sup>Foxp3-YFP<sup>+</sup>CD44<sup>low</sup>CD62L<sup>high</sup> cTregs and TCRβ<sup>+</sup>CD4<sup>+ </sup>Foxp3-YFP<sup>+</sup>CD44<sup>low</sup>CD62L<sup>high</sup> eTregs derived from the spleen of 7- to 11-day-old perinatal control or <i>Foxp3</i><sup>Cre</sup><i>Pik3c3</i><sup>fl/fl</sup> mice, as determined by flow cytometry analysis (<i>n</i> = 15 for control and 14 for <i>Foxp3</i><sup>Cre</sup><i>Pik3c3</i><sup>fl/fl</sup> for both CellROX and MitoSOX). (<b>C</b>) GSEA enrichment plot showing decreased Hallmark TNFα signaling via NFκB signature in Vps34-deficient versus control terminal eTregs from single-cell transcriptome profiling (as described in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#pbio.3003074.g003" target="_blank">Fig 3</a>). …”
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4056
Atg14 plays a cell-intrinsic role in orchestrating eTreg survival but not terminal differentiation.
Published 2025“…Jun/Fos transcription factors with predicted decreased activity in Atg14-deficient versus control eTregs are labeled. …”
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4057
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4058
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4059
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4060