Data Sheet 1_Identification of telomere-related gene subtypes and prognostic signatures in osteosarcoma.xlsx حسب Zhaoguang Song (20778602)

"…Finally, we discovered that expression of PDK2, PPARG, MORC4, SP110, TERT and MAP3K5 was significantly decreased in OS cells.</p>Conclusion<p>In conclusion, our study has uncovered the importance of TRGs in defining distinct subtypes of OS with different survival outcomes and immune contexts. …"

Image 1_Effects of dietary fiber on Chinese children with functional constipation and targeted modification of gut microbiota and related metabolites.pdf حسب Pei Xiao (466657)

"…At the genus level, the relative abundances of Lachnospiraceae_ND3007_group, Lactococcus, Prevotella, and Anaerofustis significantly increased, whereas Enterobacter, DTU089, and Sutterella showed significant decreases. …"

Figure 5 from Multiplexed Imaging Mass Cytometry Reveals Tumor-immune Microenvironment–dependent Hormone Receptor Expression in Adult-Type Ovarian Granulosa Cell Tumors حسب Eleonora Y. Khlebus (20814571)

"…Top 10 GO terms for every category are presented. <b>G,</b> Top significantly enriched gene sets from MSigDB hallmark gene sets revealed by GSEA. …"

Divergent Oncogenic Signaling and Immune Microenvironment Changes in Low-Grade Serous Ovarian Cancer Undergoing Intraperitoneal Treatment حسب Isaac Bishara (21157583)

"…Conversely, the responder showed downregulation of proliferation-associated pathways, reduced translational activity, and decreased UPR stress signaling, accompanied by compensatory activation of alternative survival pathways including PI3K, Wnt/β-catenin, and Notch signaling. single-nuclei archetype analysis identified dynamic shifts between metabolic and PI3K/immune-enriched subpopulations, highlighting adaptive tumor plasticity under therapeutic pressure. …"

Data Sheet 1_Comprehensive analysis of metabolism-related genes in sepsis reveals metabolic–immune heterogeneity and highlights GYG1 as a potential therapeutic target.csv حسب Jie Zheng (31208)

"…Mechanistically, Gyg1 knockdown significantly reduced glycogen content in myeloid cells, attenuated IL-6 and TNF-α production, alleviated LPS-induced neutrophil, and modestly decreased CD40 expression in monocytes and dendritic cells. …"

DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

"…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"

Table 1_Transcriptional patterns of brain structural abnormalities in CSVD-related cognitive impairment.docx حسب Haixia Mao (3775582)

"…Furthermore, a total of 1,580 genes were revealed to be significantly associated with regional change in GMV. …"

Data Sheet 2_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).pdf حسب Bingbu Li (21097373)

"…These differentially expressed genes were significantly enriched in oxidation-reduction, ferroptosis, steroid biosynthesis, and apoptosis pathways.…"

Table 1_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).xls حسب Bingbu Li (21097373)

"…These differentially expressed genes were significantly enriched in oxidation-reduction, ferroptosis, steroid biosynthesis, and apoptosis pathways.…"

Image 1_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).tif حسب Bingbu Li (21097373)

"…These differentially expressed genes were significantly enriched in oxidation-reduction, ferroptosis, steroid biosynthesis, and apoptosis pathways.…"

Figure 2 from Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell Composition but Differ in Immune Cell Phenotypes حسب Laura Kuett (20493991)

"…Circles display significantly enriched (red) or decreased (blue; FDR < 0.05; multiple testing correction with the Benjamin–Hochberg method) results, with size indicating the log-transformed fold change.…"

Table 1_Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer.... حسب Francisco Alejandro Lagunas-Rangel (13849122)

"…Affected kinases were significantly enriched in cancer-associated pathways, including insulin signaling, EGF–EGFR signaling, PI3K/AKT signaling, and the PD-L1/PD-1 immune checkpoint axis. …"

Supplementary file 1_Transcriptional and neurotransmitter signatures of cerebral spontaneous neural activity in nurses with burnout.docx حسب Chun-Mei Song (21716903)

"…The fALFF t-map was spatially correlated with Allen Human Brain Atlas gene expression (followed by gene ontology enrichment) and neurotransmitter system maps.</p>Results<p>Nurses with burnout exhibited significantly decreased precuneus fALFF and reduced precuneus-right dorsolateral prefrontal cortex (DLPFC) FC compared to controls. …"

Data Sheet 1_Pan-cancer analysis reveals TRA16 as a master regulator of human carcinogenesis.pdf حسب Yanyan Zhu (32035)

"…In liver cancer organoid models, TRA16 and its co-expressed genes were significantly upregulated. Intercellular communication analysis showed that TRA16-positive cells exhibited increased autocrine signaling and overall signaling activity. …"

Data Sheet 3_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).pdf حسب Bingbu Li (21097373)

"…These differentially expressed genes were significantly enriched in oxidation-reduction, ferroptosis, steroid biosynthesis, and apoptosis pathways.…"

Prognostic value of miR-378c in hepatocellular carcinoma and its regulatory effect on tumor progression حسب Yuanjie Bao (21075400)

"…Bioinformatics analysis of miR-378c target genes revealed that miR-378c target genes were enriched in tumor-associated pathways.</p> <p>Serum miR-378c expression is decreased in HCC patients and strongly connected with poor prognosis. …"

Data Sheet 1_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).pdf حسب Bingbu Li (21097373)

"…These differentially expressed genes were significantly enriched in oxidation-reduction, ferroptosis, steroid biosynthesis, and apoptosis pathways.…"

Data Sheet 1_Silencing ATF3 mediates mitochondrial homeostasis and improves ischemic stroke through regulating the MAPK signaling pathway.docx حسب Haifengqing Li (21575201)

"…Notably, silencing ATF3 significantly inhibited the production of reactive oxygen species (ROS), increased the concentrations of ATP and NAD+, and upregulated the expression of MFN1 and MFN2. …"

Table 1_Disorders of acid-base balance promote rumen lipopolysaccharide biosynthesis in dairy cows by modulating the microbiome.xls حسب Guobin Hou (20207727)

"…Introduction<p>Disorders of acid-base balance in the rumen of dairy cows have a significant impact on their health and performance. …"

Image 1_Disorders of acid-base balance promote rumen lipopolysaccharide biosynthesis in dairy cows by modulating the microbiome.jpeg حسب Guobin Hou (20207727)

"…Introduction<p>Disorders of acid-base balance in the rumen of dairy cows have a significant impact on their health and performance. …"