Search alternatives:
significantly enriched » significantly enhanced (Expand Search), significantly increased (Expand Search), significantly decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
enriched decrease » enrichment decreases (Expand Search)
significantly enriched » significantly enhanced (Expand Search), significantly increased (Expand Search), significantly decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
enriched decrease » enrichment decreases (Expand Search)
-
1061
Image2_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png
Published 2024“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”
-
1062
Image1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png
Published 2024“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”
-
1063
Image 2_Standardized aqueous extract of Abutilon theophrasti Medic. ameliorates oxidative stress and inflammatory responses against hydrochloric acid/ethanol-induced gastric ulcer...
Published 2025“…In vitro, ATAE treatment significantly lowered nitric oxide (NO) and reactive oxygen species (ROS) production, attenuated nuclear translocation of NF-κB p65, and modulated mRNA expression levels of NF-κB-regulated mediators, including TNF-α, IL-1β, IL-6, MnSOD, GSH-Px, CAT, VCAM-1, and MMP-9. …”
-
1064
Image 1_Standardized aqueous extract of Abutilon theophrasti Medic. ameliorates oxidative stress and inflammatory responses against hydrochloric acid/ethanol-induced gastric ulcer...
Published 2025“…In vitro, ATAE treatment significantly lowered nitric oxide (NO) and reactive oxygen species (ROS) production, attenuated nuclear translocation of NF-κB p65, and modulated mRNA expression levels of NF-κB-regulated mediators, including TNF-α, IL-1β, IL-6, MnSOD, GSH-Px, CAT, VCAM-1, and MMP-9. …”
-
1065
Table 4_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
-
1066
Table 2_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
-
1067
Table 3_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
-
1068
Table 1_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.docx
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
-
1069
Table 5_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
-
1070
Table 6_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
-
1071
Data Sheet 2_Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy.zip
Published 2025“…The immune infiltration analysis showed that there was a significantly increased abundance of macrophages and a decreased abundance of CD4 and CD8 T cells, including Tr1, nTreg, Tfh, CD8 naïve, cytotoxic T cells and effector memory T cells in the epilepsy group. …”
-
1072
Data Sheet 1_Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy.zip
Published 2025“…The immune infiltration analysis showed that there was a significantly increased abundance of macrophages and a decreased abundance of CD4 and CD8 T cells, including Tr1, nTreg, Tfh, CD8 naïve, cytotoxic T cells and effector memory T cells in the epilepsy group. …”
-
1073
Image 1_Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy.tif
Published 2025“…The immune infiltration analysis showed that there was a significantly increased abundance of macrophages and a decreased abundance of CD4 and CD8 T cells, including Tr1, nTreg, Tfh, CD8 naïve, cytotoxic T cells and effector memory T cells in the epilepsy group. …”
-
1074
Supplementary file 1_Ultrafine garlic powder alleviates non-alcoholic steatohepatitis by inhibiting hepatocyte ferroptosis and modulating ERK-dependent oxidative stress.docx
Published 2025“…Fibrosis-related mRNA and pro-inflammatory mRNA expression were significantly decreased. Western blot results showed that UGP significantly inhibited the activation of p-ERK signaling. …”
-
1075
Supplementary file 1_Vegetation C: N: P stoichiometry and ecosystem carbon storage under different grazing patterns on the Tibetan Plateau.docx
Published 2025“…Introduction<p>Grazing is a significant driver of grassland ecosystems changes, but the relationship between plant functional groups’ carbon (C): nitrogen (N): phosphorus (P) stoichiometry ratios and ecosystem C storage under different grazing management patterns remains uncertain.…”
-
1076
Proteomics analysis comparing dsProsβ1- and dsmGFP-fed cabbage stem flea beetle adults.
Published 2024“…Proteins showing significant differential abundance were subjected to Gene Ontology (GO) enrichment analysis using the R package clusterProfiler (v3.17). …”
-
1077
Effects of exogenous phytohormone 5-ALA on fruit quality and volatile metabolites of ' Meizao ' sweet cherry
Published 2025“…At the same time, the anthocyanin content decreased significantly by 64.47% compared with the control, whereas the contents of flavonoids, total phenols, and tannins increased by 114.62%, 7.80%, and 1.67%, respectively. …”
-
1078
De-repression of endogenous retroelements triggers viral mimicry, interferon, and cytokine response.
Published 2025“…<b>(F)</b> GSEA reveals that the “response to virus” pathway is significantly enriched in ATRX-null microglia. NES, normalized enrichment score. …”
-
1079
Data Sheet 1_Serum metabolomics reveal the mechanisms by which fermented brewer’s spent grains promote intestinal development in white-feathered broilers.zip
Published 2025“…Specifically, key DEMs involved in amino acid metabolism included significantly increased phenylalanine levels and decreased 4-HPA and 3-HPA levels (p < 0.05). …”
-
1080
Supplementary file 2_Gut microbiome and serum metabolome alterations in osteosarcoma patients.xlsx
Published 2025“…Principal component analysis identified 33 microbial species that exhibited significant changes in osteosarcoma patients. Of note, the relative abundance of Alloprevotella and Prevotella increased in these patients. …”