Supplementary file 1_Gut microbiome and serum metabolome alterations in osteosarcoma patients.docx by Chao Li (145513)

“…Principal component analysis identified 33 microbial species that exhibited significant changes in osteosarcoma patients. Of note, the relative abundance of Alloprevotella and Prevotella increased in these patients. …”

HSP47 inhibitor Col003 may attenuates neurological impairment in chronic ischemic stroke rats by inhibiting LCN2 by Kejian Zhou (22557101)

“…</p> <p>Fourteen days post-MCAO, Col003 treatment significantly decreased cerebral infarct volume and enhanced neurological function scores in rats. …”

Data Sheet 1_Radiomics reveals the biological basis for non-small cell lung cancer prognostic stratification by reflecting tumor immune microenvironment heterogeneity.docx by Qing Huang (240196)

“…Immune microenvironment profiling showed significantly reduced immune scores and decreased proportions of naive B cells in high-risk patients, indicating impaired immune activity. …”

Table 1_Bacillus megaterium NCT-2 agent alters soil nutrients, vegetable quality, and root microecology in secondary salinized soil.docx by Yimin You (11465812)

“…The chlorophyll a, chlorophyll b, carotenoids, and total chlorophyll were significantly increased by the agent. Critically, high-throughput sequencing revealed NCT-2-driven enrichment of stress-resilient taxa (e.g., Firmicutes, Acidobacteria) and functional synergists (e.g., Acetobacter), which correlated with soil nutrient fluxes and plant antioxidant capacity. …”

Supplementary file 1_Bacillus megaterium NCT-2 agent alters soil nutrients, vegetable quality, and root microecology in secondary salinized soil.docx by Yimin You (11465812)

“…The chlorophyll a, chlorophyll b, carotenoids, and total chlorophyll were significantly increased by the agent. Critically, high-throughput sequencing revealed NCT-2-driven enrichment of stress-resilient taxa (e.g., Firmicutes, Acidobacteria) and functional synergists (e.g., Acetobacter), which correlated with soil nutrient fluxes and plant antioxidant capacity. …”

Table 2_Bacillus megaterium NCT-2 agent alters soil nutrients, vegetable quality, and root microecology in secondary salinized soil.docx by Yimin You (11465812)

“…The chlorophyll a, chlorophyll b, carotenoids, and total chlorophyll were significantly increased by the agent. Critically, high-throughput sequencing revealed NCT-2-driven enrichment of stress-resilient taxa (e.g., Firmicutes, Acidobacteria) and functional synergists (e.g., Acetobacter), which correlated with soil nutrient fluxes and plant antioxidant capacity. …”

date-Guo.xlsx by zengpeng Guo (20696411)

“…</a>We monitored/investigated plant community, seed rain, seed bank, seedlings, rodents, and litter along an N enrichment gradient in an alpine meadow. We found that the N enrichment significantly decreased the species diversity of seed rain, seed bank, and seedling, ultimately resulting in the loss of plant diversity. …”

Table 3_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.xlsx by Hongyu Zhou (352858)

“…Western blot analysis further confirmed DHM-mediated suppression of apoptosis through regulation of p53, Bax, cleaved caspase-3, and Bcl-2 expression. High-dose DHM significantly attenuated retinal thinning (10.7% reduction), decreased pigment loss, and ameliorated structural disorganization in the outer nuclear layer (ONL). …”

Image 1_Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.tif by Peng Zhang (2071)

“…</p>Results<p>Functional and pathway enrichment analysis demonstrated that BBR significantly modulated the inflammation-related signaling pathways of AS. …”

Table 2_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.docx by Hongyu Zhou (352858)

“…Western blot analysis further confirmed DHM-mediated suppression of apoptosis through regulation of p53, Bax, cleaved caspase-3, and Bcl-2 expression. High-dose DHM significantly attenuated retinal thinning (10.7% reduction), decreased pigment loss, and ameliorated structural disorganization in the outer nuclear layer (ONL). …”

Table 1_Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.docx by Peng Zhang (2071)

“…</p>Results<p>Functional and pathway enrichment analysis demonstrated that BBR significantly modulated the inflammation-related signaling pathways of AS. …”

Table 1_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.docx by Hongyu Zhou (352858)

“…Western blot analysis further confirmed DHM-mediated suppression of apoptosis through regulation of p53, Bax, cleaved caspase-3, and Bcl-2 expression. High-dose DHM significantly attenuated retinal thinning (10.7% reduction), decreased pigment loss, and ameliorated structural disorganization in the outer nuclear layer (ONL). …”

Supplementary file 1_Translocator protein deficiency blocks the ferroptosis of malignant peripheral nerve sheath tumors through glutathione peroxidase 4.pdf by Xiaoli Zhang (135098)

“…TSPO-knockdown MPNST cells exhibited significant resistance to ferroptotic cell death. Additionally, biochemical characterization indicated that TSPO deficiency decreased intracellular Fe²⁺ and ROS. …”

Table 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.docx by Feifei Yang (334047)

“…</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…”

Image 4_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…”

Image 2_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…”

Table 2_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.doc by Feifei Yang (334047)

“…</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…”

Image 3_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…”

Table 3_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.xlsx by Feifei Yang (334047)

“…</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…”

Image 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…</p>Conclusions<p>Collectively, this study reveals the significance of iron overload in remodeling hematopoietic ecosystem and affecting HSC and LAM function in AML, providing new insights into the multifaceted role of iron overload in leukemia.…”