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significantly estimated » significantly mitigated (Expand Search), significant estimates (Expand Search), significantly overestimated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
estimated decrease » estimated release (Expand Search)
significantly estimated » significantly mitigated (Expand Search), significant estimates (Expand Search), significantly overestimated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
estimated decrease » estimated release (Expand Search)
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1141
Image 2_Global, regional, and national epidemiology of congenital heart disease in children from 1990 to 2021.tif
Published 2025“…Background<p>Congenital heart disease (CHD) is a leading cause of morbidity and mortality in children globally, with significant variations in outcomes across different regions.…”
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1142
Table 1_Global, regional, and national epidemiology of congenital heart disease in children from 1990 to 2021.docx
Published 2025“…Background<p>Congenital heart disease (CHD) is a leading cause of morbidity and mortality in children globally, with significant variations in outcomes across different regions.…”
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1143
Table 2_Global, regional, and national burden of acute hepatitis (1990–2021): a systematic analysis of the global burden of disease in 2021.xlsx
Published 2025“…</p>Conclusion<p>While global AVH burden is decreasing, significant disparities persist, warranting tailored interventions to enhance resource equity in high-SDI regions and strengthen healthcare infrastructure in low-SDI areas.…”
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1144
Table 4_Global, regional, and national epidemiology of congenital heart disease in children from 1990 to 2021.docx
Published 2025“…Background<p>Congenital heart disease (CHD) is a leading cause of morbidity and mortality in children globally, with significant variations in outcomes across different regions.…”
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1145
Image 1_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.tif
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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1146
Table 2_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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1147
Table 1_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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1148
Table 1_Global, regional, and national burden of acute hepatitis (1990–2021): a systematic analysis of the global burden of disease in 2021.docx
Published 2025“…</p>Conclusion<p>While global AVH burden is decreasing, significant disparities persist, warranting tailored interventions to enhance resource equity in high-SDI regions and strengthen healthcare infrastructure in low-SDI areas.…”
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1149
Table 2_Global, regional, and national epidemiology of congenital heart disease in children from 1990 to 2021.docx
Published 2025“…Background<p>Congenital heart disease (CHD) is a leading cause of morbidity and mortality in children globally, with significant variations in outcomes across different regions.…”
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1150
Table 3_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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1151
Image 1_Global, regional, and national epidemiology of congenital heart disease in children from 1990 to 2021.tif
Published 2025“…Background<p>Congenital heart disease (CHD) is a leading cause of morbidity and mortality in children globally, with significant variations in outcomes across different regions.…”
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1152
Algorithms for designing continuous curricula A: Decision tree showing the continuous version of ADP which includes actions that “grow” and “shrink” the increments between continuo...
Published 2025“…<p>See the text for more details of the task in the continuous setting. B: ADP significantly outperforms INC when the task is difficult (low <i>ε</i>). …”
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1153
Data Sheet 1_Global burden of disease among adolescents and young adults with drug use disorders, 1990–2021: based on GBD 2021.doc
Published 2025“…Additionally, we assessed the trend of the estimated annual percentage change (EAPC).</p>Results<p>Globally, the ASIR of new DUD cases among adolescents and young adults exhibited a decreasing trend from 1990 to 2021, with an EAPC of −0.46 (95% confidence interval: −0.52, −0.39). …”
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1154
Table 2_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…</p>Conclusions<p>While significant progress has been made in reducing the global burden of pediatric IE, major geographic and socio-demographic inequalities persist. …”
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1155
Table 1_Global, regional, and national disease burden and economic costs of cervical cancer (1991–2021): a multidimensional data synthesis analysis.docx
Published 2025“…Objectives<p>Cervical cancer remains a significant global health concern, particularly in less developed regions. …”
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1156
Table 1_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…</p>Conclusions<p>While significant progress has been made in reducing the global burden of pediatric IE, major geographic and socio-demographic inequalities persist. …”
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1157
Table 3_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…</p>Conclusions<p>While significant progress has been made in reducing the global burden of pediatric IE, major geographic and socio-demographic inequalities persist. …”
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1158
Data Sheet 1_Global, regional, and national epidemiology of otitis media in children from 1990 to 2021.docx
Published 2025“…Key risk factors identified include secondhand smoke, particulate matter pollution, low birth weight, and short gestation. Additionally, a significant inverse association was found between the SDI and the burden of OM, with age-standardized DALY rates decreasing markedly as SDI increased.…”
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1159
Table 1_Associations between systemic inflammatory indices and the risk of renal function decline in patients with type 2 diabetes mellitus: a retrospective cohort study.docx
Published 2025“…Renal function decline was defined as an estimated glomerular filtration rate decreasing by ≥ 40% from baseline. …”
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1160
Data Sheet 1_Global, regional, and national burden of ischemic heart disease attributed to non-optimal temperature, 1990–2021: an age-period-cohort analysis of the global burden of...
Published 2025“…Background<p>In recent years, non-optimal temperature has significantly impacted global health including ischemic heart disease (IHD).…”