DataSheet1_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…Cochran Q test was used to evaluate SNP estimate heterogeneity. MR-Egger and MR-PRESSO methods were utilized to detect horizontal pleiotropy.…”

Table 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx by Mattia Dalle Nogare (22696022)

“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”

Table 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx by Mattia Dalle Nogare (22696022)

“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”

Supplementary Material for: The Association Between Tumor Necrosis Factor-Alpha Inhibitor Use and Dementia Risk in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-... by figshare admin karger (2628495)

“…The pooled meta-analysis comparing the risk of dementia (hazard ratio [HR] = 0.77, 95% CI 0.64–0.93) and Alzheimer's disease (AD) (odds ratio = 0.31, 95% CI 0.23–0.43) between TNFi users and non-users showed a significant association. However, the pooled HR for AD risk was inconsistent. …”

DataSheet3_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…Cochran Q test was used to evaluate SNP estimate heterogeneity. MR-Egger and MR-PRESSO methods were utilized to detect horizontal pleiotropy.…”

Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx by Mattia Dalle Nogare (22696022)

“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”

DataSheet5_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…Cochran Q test was used to evaluate SNP estimate heterogeneity. MR-Egger and MR-PRESSO methods were utilized to detect horizontal pleiotropy.…”

DataSheet2_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…Cochran Q test was used to evaluate SNP estimate heterogeneity. MR-Egger and MR-PRESSO methods were utilized to detect horizontal pleiotropy.…”

DataSheet8_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.zip by Yongming Du (807059)

“…Cochran Q test was used to evaluate SNP estimate heterogeneity. MR-Egger and MR-PRESSO methods were utilized to detect horizontal pleiotropy.…”

Data Sheet 1_Spatial–temporal evolution and associated factors of older adult care institutions in Shanghai.xlsx by Xingxing Yin (7919447)

“…</p>Results<p>The number of older adult care institutions in Shanghai has seen significant growth over the past 20 years, increasing fourfold due to the rise in both public and private facilities. …”

Table 1_Effects of singing on vascular health in older adults with coronary artery disease: a randomized, crossover trial.docx by Mehri Bagherimohamadipour (21189317)

“…When assessing post- to pre- change, the live singing intervention showed a significant change of −0.62 ms² (SE 0.29, p = 0.036) in LnHF power.…”

Inference of cell-type proportions from bulk RNAseq and dynamics during myocardial infarction in α1A-AR-KO mice. by Brian Gural (21781982)

“…<b>(C)</b> Validation of the deconvolution pipeline using bulk RNAseq from pure cell type fractions as ground-truth samples, depicted in a ternary plot where each dot represents a replicate, color-coded by intended enriched cell type, indicating high accuracy of the composition estimates. <b>(D)</b> Estimation of cardiac cell type composition changes post-myocardial infarction (MI) and in α1A-AR knockout (cmAKO) mice, showing increased proportions of macrophages and fibroblasts and decreased proportions of cardiomyocytes, with more pronounced changes in cmAKO mice. …”

Table_1_Construction of a risk screening and visualization system for pulmonary nodule in physical examination population based on feature self-recognition machine learning model.X... by Fang Tian (360682)

“…A visualization system was created to estimate the risk of developing pulmonary nodules.</p>Results<p>Multivariable analysis identified older age, smoking or passive smoking, high psychological stress within the past year, occupational exposure (e.g., air pollution at the workplace), presence of chronic lung diseases, and elevated carcinoembryonic antigen levels as significant risk factors for pulmonary nodules. …”

Data Sheet 1_OvaRePred (HerTempo): an enhanced ovarian aging clock for personalized reserve assessment, endocrine age modeling, and predicting reproductive milestones across the fe... by Huiyu Xu (12255545)

“…AMH sampling on different cycle days showed only modest effects from minor fluctuations; only substantial AMH decreases significantly affected prediction accuracy. …”

Table 9_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis... by Tessa Rose Cornell (15460726)

“…HCF infection prevalence in horses and donkeys was 22.0% (n = 102/463, 95% CI 18.3–26.1%) and 5.4% (n = 5/92, 95% CI 1.8–12.2%), respectively. No significant agreement was measured between LAT and nested ITS-PCR results (κ < 0.00).…”

Table 1_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis... by Tessa Rose Cornell (15460726)

“…HCF infection prevalence in horses and donkeys was 22.0% (n = 102/463, 95% CI 18.3–26.1%) and 5.4% (n = 5/92, 95% CI 1.8–12.2%), respectively. No significant agreement was measured between LAT and nested ITS-PCR results (κ < 0.00).…”

Table 2_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis... by Tessa Rose Cornell (15460726)

“…HCF infection prevalence in horses and donkeys was 22.0% (n = 102/463, 95% CI 18.3–26.1%) and 5.4% (n = 5/92, 95% CI 1.8–12.2%), respectively. No significant agreement was measured between LAT and nested ITS-PCR results (κ < 0.00).…”

Table 10_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis... by Tessa Rose Cornell (15460726)

“…HCF infection prevalence in horses and donkeys was 22.0% (n = 102/463, 95% CI 18.3–26.1%) and 5.4% (n = 5/92, 95% CI 1.8–12.2%), respectively. No significant agreement was measured between LAT and nested ITS-PCR results (κ < 0.00).…”

Table 3_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis... by Tessa Rose Cornell (15460726)

“…HCF infection prevalence in horses and donkeys was 22.0% (n = 102/463, 95% CI 18.3–26.1%) and 5.4% (n = 5/92, 95% CI 1.8–12.2%), respectively. No significant agreement was measured between LAT and nested ITS-PCR results (κ < 0.00).…”

Table 8_Exploring Histoplasma species seroprevalence and risk factors for seropositivity in The Gambia’s working equid population: Baseline analysis of the Tackling Histoplasmosis... by Tessa Rose Cornell (15460726)

“…HCF infection prevalence in horses and donkeys was 22.0% (n = 102/463, 95% CI 18.3–26.1%) and 5.4% (n = 5/92, 95% CI 1.8–12.2%), respectively. No significant agreement was measured between LAT and nested ITS-PCR results (κ < 0.00).…”