Structural analysis of wild type and mutated variants of CXCR4. by Bonoshree Sarkar (20469331)

“…The changes in H-bond in the 3D structure of the CXCR4 protein likely have a significant impact on the structure functions of the protein.…”

Data_Sheet_1_A randomized double-blinded study assessing the effect of different doses of transnasal dexmedetomidine on the median effective concentration of ropivacaine for a caud... by Fu Wang (10556)

“…Compared to group IN-NS, the EC50 value of ropivacaine in IN-DEX2 was significantly decreased by 21.4% (p = 0.001), while there was no significant difference between group IN-NS and IN-DEX1 (p = 0.125). …”

Unraveling the Effects of Epigallocatechin-3-gallate on Hepatocellular Carcinoma Cells: A Comparative Analysis of Monolayer vs Multicellular Tumor Spheroids by Mariana dos Reis Simpronio (21876938)

“…The cell culture condition influenced EGCG effects on gene expression and cell viability, with more significant effects in monolayer than in MTS. After 15 days, control MTS showed cellular dissociation, whereas EGCG-treated MTS showed decreased cell viability and no growth. …”

Loss of H2A.Z from transcription start sites was correlated with, but not required for, HU-induced gene activation. by Hilary T. Brewis (11798006)

“…The p-values, generated using hypergeometric probability, indicate if the overlap in each group was significantly greater (red) or less (blue) than excepted by chance (black = non-significant). …”

Effectiveness of Interventions to Reduce Sedentary Behaviour in People with Chronic Obstructive Pulmonary Disease: A Systematic Review of Randomised Controlled Trials by Stefanie Harding (21025237)

“…</p> <p>1086 studies were identified; six met inclusion criteria, and two reported a decreased sedentary time. Nordic walking reduced sedentary time by 128 minutes/day compared to baseline, significantly more than the control group (<i>p</i> < 0.01). …”

Data Sheet 2_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.pdf by Linjie Peng (12553717)

“…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …”

Data Sheet 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf by Mattia Dalle Nogare (22696022)

“…</p>Results<p>CIBERSORTx demonstrated the highest sensitivity (r > 0.85) for detecting pituitary cell types, although accuracy decreased for TME components. Application to ten GH-secreting PitNETs with known histological contamination and to public datasets consistently revealed residual normal tissue across hormone-secreting subtypes, excluding silent tumors. …”

Data Sheet 1_Duodenal obstruction due to two congenital bands: a case report and literature review.pdf by Shiqiu Xiong (238109)

“…Physical examination revealed abdominal tenderness and decreased bowel sounds. Contrast x-ray showed an obstructed passage of contrast through the third part of the duodenum. …”

DataSheet2_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.docx by Marek Sierzega (3846406)

“…However, the analysis of paired samples failed to demonstrate a decreasing concentration gradient between the portal and peripheral blood for any of the myokines, evidencing against their release by the primary tumour. …”

Life Cycle Assessment to Quantify Global Warming and Human Health–Respiratory Impacts of Using Composites from Waste Wind Turbine Blades as Feedstock for Cement Clinker and Fibergl... by Caroline V. Cameron (22355207)

“…The increasing deployment of wind turbines also creates significant waste when turbine materials reach their end-of-life. …”

Data Sheet 1_Biorefinery—inspired, two-step valorization strategy to manage plant-based recalcitrant organic waste, involving solvent extraction, and fermentation with Bacillus cla... by Sreejith Meppoyilam (20563139)

“…The concentrated supernatant showed significant inhibition of Salmonella enterica and Shigella dysenteriae. …”

Supplementary file 1_Use of erythromycin and metoclopramide in hospitalized dogs: a multicenter historical cohort study.docx by Ee Fung Teo (21181196)

“…There were also significant differences in prokinetic use between institutions.…”

Table 1_Belimumab-driven reductions in retinal microvascular density assessed by optical coherence tomography angiography: insights from systemic lupus erythematosus patients.docx by Maierhaba Maitiyaer (18947791)

“…</p>Result<p>LN patients showed significantly reduced macular vascular density compared with non-LN patients. …”

Data Sheet 1_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.docx by Shirong Ruan (15414081)

“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”

Data used in the simulations. by Anna Ferretto (17473110)

“…However, there is a significant knowledge gap regarding how current and future forest management practices will affect carbon turnover time. …”

Table 1_Remission of obsessive-compulsive disorder using ketogenic metabolic therapy in support of exposure and response prevention: a retrospective case report.docx by Nicole Laurent (11870390)

“…</p>Results<p>Within three weeks of initiating KMT and subsequent ERP, daily compulsive behaviors decreased from 3–8 hours to less than one hour. Significant reductions in DOCS symmetry/ordering subscale scores were sustained at 95 weeks. …”

Data_Sheet_1_Cytomegalovirus results in poor graft function via bone marrow-derived endothelial progenitor cells.pdf by Weiran Lv (715679)

“…Introduction<p>Poor graft function (PGF), characterized by myelosuppression, represents a significant challenge following allogeneic hematopoietic stem cell transplantation (allo-HSCT) with human cytomegalovirus (HCMV) being established as a risk factor for PGF. …”

Table 2_Predicting ventilator-associated lower respiratory tract infection outcomes using sequencing-based early microbiological response: a proof-of-concept prospective study.docx by Ji Zhou (481629)

“…The RQR was calculated as the quantification of A. baumannii determined by QtNGS after treatment to pretreatment. RQR significantly increased on day 4 in the non-survival group (median 5.285), and decreased in the survival group (median 0.1864). …”

DataSheet4_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…”

Video 8_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4 by Shirong Ruan (15414081)

“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”