Data Sheet 1_Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes.docx by Michael Hesse (439701)

“…Background<p>Pregnancy significantly affects the maternal cardiovascular system, with physiological adaptations characterized by cardiac hypertrophy and increased capillarization. …”

Table 1_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx by Baixing Wei (21461966)

“…However, the change in age-standardized rates from 1990 to 2021 declined significantly. The association between the Socio-demographic Index (SDI) and the burden of amputations in 2021 was not linear. …”

Integrating legumes into cropping systems enhances soil carbon and nitrogen content while reduces the soil carbon-to-nitrogen ratio: A global meta-analysis by Zhiqiang Lu (20145192)

“…Moreover, SOC and STN increased when legumes replaced fallow or gramineous soil, whereas SCN significantly decreased only when legumes replaced gramineous systems. …”

Image 2_CT angiography-derived three-dimensional pulmonary vein topography is related to the outcome after cryoballoon ablation.tiff by Martin Saal (21267734)

“…The number of occlusion attempts in the right inferior PV was significantly higher in the PVI failure group indicating a technical more complex balloon occlusion. …”

DataSheet1_Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles.docx by Abdul Mateen (12055673)

“…Pharmacokinetic parameters such as AUC_0-t, C_max MRT, Vd, and half-life (t_1/2) were enhanced significantly (p ≤ 0.001), while clearance was considerably decreased (p ≤ 0.001) for the chosen synthesized nanoparticles in contrast to the commercially accessible sorafenib formulation (Nexavar^®). …”

Supplementary file 1_The efficacy of resveratrol in the treatment of liver fibrosis: a systematic review and meta-analysis of preclinical studies.docx by Dehua Luo (22275916)

“…</p>Conclusion<p>Resveratrol significantly alleviates liver fibrosis in animal models via anti-inflammatory and antioxidant mechanisms. …”

Image 1_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.pdf by Melissa S. Monson (8281047)

“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”

Roxadustat alleviates cisplatin-induced acute kidney injury by regulating fatty acid oxidation and mitochondrial function by Xialin Li (20449207)

“…Roxadustat also remarkably decreased the expression of KIM-1 and NGAL. Furthermore, roxadustat significantly abolished the expression of Bax and cleaved caspase 3, two apoptosis marker proteins. …”

Table 4_Outcomes after liposuction-based treatment of lymphedema: a systematic review and meta-analysis.docx by Junzhe Chen (5729912)

“…Combined approaches achieved slightly lower reductions (87.31%), but significantly decreased compression dependence, improved lymphatic function, and enhanced QOL. …”

Table 1_Evaluation of a multi-epitope vaccine PME for Pasteurella multocida in mouse model.docx by Rui Zhang (13940)

“…Furthermore, the pathological lung damages in the His-PME group and the pcDNA3.1-PME group were significantly alleviated, and the bacterial loads in lung tissues were significantly decreased. …”

Supplementary file 1_Application of multidimensional gait feature fusion algorithm in gait assessment for patients with knee osteoarthritis.docx by Yuzhe Tan (22274731)

“…The incorporation of multidimensional features significantly enhanced the performance of all classification models: under multidimensional feature input, RF, SVM, DT, and KNN achieved accuracies of 96.93%, 92.44%, 90.29%, and 88.98%, respectively—all significantly outperforming models using single‐dimensional features.…”

Image_3_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG by Bin Zhang (64682)

“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”

Supplementary Material for: Seizure Burden Before and After Lidocaine as Add-on Therapy in (a)EEG-Confirmed Neonatal Seizures by figshare admin karger (2628495)

“…After LDC administration, median TSB decreased significantly from 31 (interquartile range, IQR 16–68) to 0 minutes (IQR 0–0, p<0.01), and MSB from 10 (IQR 6–41) to 0 min/hour (IQR 0–0, p<0.01). …”

Image 4_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf by Na He (295300)

“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”

Table 2_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.xlsx by Melissa S. Monson (8281047)

“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”

Table 1_Effect of membrane rigidification on the BrAFP1 expression and cold-tolerance in Brassica rapa.docx by Xiaoyun Dong (9706099)

“…The expression levels of cold-responsive genes, including cyclic nucleotide-gated channel 1 (CNGC1), open stomata 1 (OST1), and inducer of CBF expression 1 (ICE1), as well as membrane fluidity-related genes, such as acyl-lipid desaturase 2 (ADS2), fatty acid desaturase 2 (FAD2), and sensitive to freezing 2 (SFR2), were significantly increased following DMSO pretreatment, while BA treatment significantly inhibited the expression of these genes. …”

The regulation of AsfR on tmRNA expression mediates bacterial motility and virulence in <i>aeromonas veronii</i> by Huimin Chang (12537320)

“…Consistently, the transcription level of tmRNA was significantly decreased in Δ<i>asfR</i> compared with WT of <i>A. veronii</i> by quantitative real-time PCR (RT-qPCR) analyses. …”

Data Sheet 1_Daily online adaptation enhances target coverage in prostate cancer radiotherapy: a retrospective analysis.pdf by Hanna Malygina (22545980)

“…Interquartile ranges decreased across all metrics.</p>Conclusions<p>Adaptation significantly improved target dose metrics compared to non-adapted plans, without compromising organs-at-risk sparing. …”

Modulating Aesthetic Furniture Preferences through Music: A Multimodal Neurophysiological Study Using Neural Ordinary Differential Equations Networks by Jiufang Lv (20807355)

“…</p><p dir="ltr">The findings revealed that musical intervention significantly modulated neural activity in specific frequency bands: prediction error for tactile density in the Alpha band decreased by 26.9%, while prediction accuracy for exquisiteness in the Beta band improved significantly. …”

DATA.xlsx by Zhichun Yang (21466757)

“…We found that total ecosystem ¹⁵N recovery was significantly higher under UAN than CAN during early stages (7-120 days), although this difference diminished by 365 days. …”