Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Image 3_Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005–2024.jpeg by Zheyuan Ding (4281394)

“…The reported incidence of syphilis decreased by an average of −3.53% per year across all age groups (95% CI: −4.34, −2.70%). …”

Image 2_Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005–2024.jpeg by Zheyuan Ding (4281394)

“…The reported incidence of syphilis decreased by an average of −3.53% per year across all age groups (95% CI: −4.34, −2.70%). …”

Effect of fasudil on clinical outcomes of pulmonary hypertension: a systematic review and meta-analysis by Wanying Bao (19665769)

“…<p>Pulmonary hypertension (PH) is a life-threatening condition with high mortality, categorized into Group 1-5 by distinct etiologies. …”

Table_1_Combinatorial protection of cochlear hair cells: not too little but not too much.DOCX by Arwa Kurabi (344167)

“…All compounds were added at a dosage below that required for significant protection in the assay, and only this single dose was then employed. …”

Table 1_Global burden and future trends of gastric cancer in women of reproductive age: estimates from the GBD 2021 Study, 1990–2050.xlsx by Nan Jiang (21252)

“…Although incidence is higher in men, GC remains a significant health issue for women of reproductive age (15–49 years) due to biological, hormonal, and socioeconomic factors. …”

Tectonic and metallogenic processes along the east Tethyan metallogenic domain (Lhasa-southern Tibet, Kohistan island arc and Chagai magmatic belt): a perspective review by Muhammad Hafeez (11642068)

“…Fertile porphyries display large-ion lithophile element (LILE) enrichment, high-field-strength element (HFSE) depletion, and negative Ti-Nb-Ta anomalies, consistent with oxidized magmas formed in active subduction zones with significant crustal input. …”

Table 2_Global burden and future trends of gastric cancer in women of reproductive age: estimates from the GBD 2021 Study, 1990–2050.xlsx by Nan Jiang (21252)

“…Although incidence is higher in men, GC remains a significant health issue for women of reproductive age (15–49 years) due to biological, hormonal, and socioeconomic factors. …”

Supplementary file 1_Healthy lifestyle moderates the association between recent negative life events and depressive symptoms: a cross-sectional study.docx by Yang Yang (45629)

“…The overall lifestyle was observed as significant moderating role on the association between RNLEs and depressive symptoms (OR, 95%CI: 0.61 [0.40–0.95]).…”

Table 1_Global, regional, and national disease burden and economic costs of cervical cancer (1991–2021): a multidimensional data synthesis analysis.docx by Yidi Ma (9507153)

“…Objectives<p>Cervical cancer remains a significant global health concern, particularly in less developed regions. …”

Data Sheet 1_Global burden and future trends of gastric cancer in women of reproductive age: estimates from the GBD 2021 Study, 1990–2050.zip by Nan Jiang (21252)

“…Although incidence is higher in men, GC remains a significant health issue for women of reproductive age (15–49 years) due to biological, hormonal, and socioeconomic factors. …”

Data Sheet 1_White matter functional networks in the developing brain.docx by Yali Huang (621760)

“…Additionally, 8-year-olds showed a greater distribution of brain activity energy in the high-frequency range of 0.01–0.15 Hz. Significant developmental differences in brain white matter functional networks exist between the two group, characterized by increased inter-network FC, decreased intra-network FC, and higher high-frequency energy distribution. …”

Data Sheet 1_Effective inhaler technique education is achievable - assessment and comparison of five inhaler devices errors.docx by Monika Marko (7926311)

“…Statistically significant differences in the inhalation technique assessment (before education, visit 1, and visit 2) were shown for Cyclohaler and pMDI (p < 0.0001), Turbuhaler (p = 0.0014), Diskus (p = 0.0025) and Ellipta (p = 0.0091).…”

Supplementary Material for: Delayed Onset of Central Serous Chorioretinopathy (CSCR) following corticosteroid treatment for Giant Cell Arteritis (GCA): A Case Report by figshare admin karger (2628495)

“…Following gradual tapering of his prednisone dosage, subsequent OCT confirmed significant reduction in SRF, with VA improving to 20/30 within three months. …”

Exploring the variations and potential of carbon stock in the tropical dry deciduous forests of West Bengal, India by Dipankar Bera (20798568)

“…<p>Each pool of the forest ecosystem plays a significant role, as they are interconnected and store atmospheric carbon. …”

<b><i>Acropora intermedia</i></b> genome by Wentao Han (12381793)

“…<p dir="ltr">The genus <i>Acropora</i>, notable for its diversity and widespread distribution, has recently garnered significant attention, serving as a key model for coral conservation and restoration. …”

Supplementary file 1_Characterizing rainfall patterns and dynamics in the Little Ruaha catchment, southern Tanzania.docx by Florence H. Mahay (22374706)

“…On the other hand, increasing trends which were not significant at Iringa met and Mafinga stations. In terms of seasonal rainfall, the Iringa Met and Kilima stations demonstrated decreasing trends which were significant at Kilima. …”

DataSheet1_Identification of osmotic stress resistance mediated by MdKAI2 in apple.docx by Hongyang Guo (9466516)

“…The phenotypic traits, resistance indicators, and transcriptional and metabolic regulation of MdKAI2 were identified. KAR1, a highly active form of KAR, markedly promoted the root growth of Gala cultivar tissue culture‒generated plants, possibly through increases in ABA and TZR contents and decreases in the GA3 content. …”

DataSheet2_Identification of osmotic stress resistance mediated by MdKAI2 in apple.docx by Hongyang Guo (9466516)

“…The phenotypic traits, resistance indicators, and transcriptional and metabolic regulation of MdKAI2 were identified. KAR1, a highly active form of KAR, markedly promoted the root growth of Gala cultivar tissue culture‒generated plants, possibly through increases in ABA and TZR contents and decreases in the GA3 content. …”

Data_Sheet_1_Analysis of the global burden of cardiovascular diseases linked to exposure to ambient particulate matter pollution from 1990 to 2019.docx by Binbin Zou (11358315)

“…The ASDR and DALYs increased in low-Socio-demographic Index (SDI), low–middle-SDI, and middle-SDI countries, while they decreased in high-SDI countries. The highest burden was observed in Central Asia, North Africa, the Middle East, East Asia, and South Asia. …”