يعرض 6,301 - 6,320 نتائج من 6,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significantly high decrease ))~', وقت الاستعلام: 0.30s تنقيح النتائج
  1. 6301

    Data Sheet 1_Metabolic adaptation to acute metabolic stress via PFKFB3 upregulation in rodent beta cells.doc حسب Koki Chiba (5413028)

    منشور في 2025
    "…Introduction<p>Pancreatic beta cells undergo metabolic remodeling in response to metabolic overload, but the functional significance of this remains unclear. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) is a glycolytic regulator that may play a role in beta cell adaptation under acute metabolic stress. …"
  2. 6302

    Image 2_A natural PCID2-Targeting compound suppresses hepatocellular carcinoma progression: evidence from structure-based discovery and biological evaluation.jpeg حسب Zebanuer Yuemaierjiang (22702064)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) is a highly aggressive malignancy with limited therapeutic options and poor prognosis, highlighting the urgent need for novel targets and effective agents. …"
  3. 6303

    Supplementary file 1_A natural PCID2-Targeting compound suppresses hepatocellular carcinoma progression: evidence from structure-based discovery and biological evaluation.docx حسب Zebanuer Yuemaierjiang (22702064)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) is a highly aggressive malignancy with limited therapeutic options and poor prognosis, highlighting the urgent need for novel targets and effective agents. …"
  4. 6304

    Table 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.xlsx حسب Jing Wang (6206297)

    منشور في 2025
    "…Functionally, knocking down ACTR6 inhibited cell migration and proliferation, produced a G1 cell cycle arrest, and decreased the viability of liver cancer cells.</p>Conclusion<p>These findings demonstrate that ACTR6 is highly expressed in HCC and is associated with poor prognosis. …"
  5. 6305

    Table_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.docx حسب György Szklenarik (20296893)

    منشور في 2024
    "…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …"
  6. 6306

    Data_Sheet_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.DOCX حسب György Szklenarik (20296893)

    منشور في 2024
    "…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …"
  7. 6307

    Image 1_A natural PCID2-Targeting compound suppresses hepatocellular carcinoma progression: evidence from structure-based discovery and biological evaluation.png حسب Zebanuer Yuemaierjiang (22702064)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) is a highly aggressive malignancy with limited therapeutic options and poor prognosis, highlighting the urgent need for novel targets and effective agents. …"
  8. 6308

    Image 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.tif حسب Jing Wang (6206297)

    منشور في 2025
    "…Functionally, knocking down ACTR6 inhibited cell migration and proliferation, produced a G1 cell cycle arrest, and decreased the viability of liver cancer cells.</p>Conclusion<p>These findings demonstrate that ACTR6 is highly expressed in HCC and is associated with poor prognosis. …"
  9. 6309

    Chromatin accessibility profiling of Treg cells in acute urticaria حسب Leilei Wen (3551444)

    منشور في 2025
    "…We found that <i>IL1B</i> gene expression was also significantly increased in the skin lesions of both chronic spontaneous urticaria and solar urticaria compared to healthy controls. …"
  10. 6310

    Image 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.tif حسب Jing Wang (6206297)

    منشور في 2025
    "…Functionally, knocking down ACTR6 inhibited cell migration and proliferation, produced a G1 cell cycle arrest, and decreased the viability of liver cancer cells.</p>Conclusion<p>These findings demonstrate that ACTR6 is highly expressed in HCC and is associated with poor prognosis. …"
  11. 6311

    Table 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.docx حسب Jing Wang (6206297)

    منشور في 2025
    "…Functionally, knocking down ACTR6 inhibited cell migration and proliferation, produced a G1 cell cycle arrest, and decreased the viability of liver cancer cells.</p>Conclusion<p>These findings demonstrate that ACTR6 is highly expressed in HCC and is associated with poor prognosis. …"
  12. 6312

    Data collected from pregnant women for the analysis of placental anemia, placental malaria, Cytokines and birth anthropometric indices حسب Bamgboye Morakinyo Afolabi (16838970)

    منشور في 2025
    "…Women leaving in malaria endemic areas are at high risks for malaria infections and they might acquire significant clinical immunity before pregnancy, and placental malaria, though often asymptomatic, could have harmful effects on the fetus [10]. …"
  13. 6313

    Supplementary Material for: Urinary lactate-to-creatinine ratio during the first days of life correlates with the degree of brain damage in premature infants حسب Zasada M. (20394470)

    منشور في 2024
    "…Only the GBAS moderate+severe subgroup presented with a secondary increase in the ULCR on the 3rd DOL, whereas in the GBAS normal or mild, the ULCR oscillated around similar values or gradually decreased. Significant positive correlations were detected between the ULCR on the 3rd DOL and the lactate/creatinine and lactate/N-acetyl aspartate ratios measured via 1H-MRS at TEA (r=0.308; p=0.022 and r=0.334; p=0.013, respectively). …"
  14. 6314

    Image 1_The replication protein of duck circovirus unwinds dsDNA in an ATP-driven and metal ion-dependent manner from 3′ to 5′.pdf حسب Lihan Tao (20888465)

    منشور في 2025
    "…<p>Duck circovirus (DuCV) causes immunosuppression, co-infection and increased mortality in ducks, and the prevalence and infection rate of DuCV have risen in recent years, resulting in significant economic losses to the duck industry. Studying the mechanism of virus replication is particularly important for controlling DuCV infection. …"
  15. 6315

    Supplementary Material for: Light exposure on alertness after wake-up in healthy men: Comparing dim, bright, red and blue light حسب Mekschrat L. (19669585)

    منشور في 2024
    "…However, dim vs. bright light and RT did not interact (p = .758). Chronotype was a significant covariate in the interaction of dim vs. bright light and subjective sleepiness (p = .008). …"
  16. 6316

    Data Sheet 1_Self-esteem and peer pressure susceptibility mediating the link between maternal behavior and adolescent risk behaviors.pdf حسب Marija Milić (10895373)

    منشور في 2025
    "…Although parental influence decreases and peer influence increases during this time, parental behavior still plays a significant role. …"
  17. 6317

    Table 1_Biliary microbiota in disease-free, obstructive and post-drainage biliary tracts.docx حسب Guiyuan Zhang (13994877)

    منشور في 2025
    "…Furthermore, the increased incidence of bacterial infections following biliary drainage poses a significant clinical concern; however, the relationship between biliary drainage and biliary flora remains poorly understood. …"
  18. 6318

    Aquaporin and red cell O2 permeability حسب S. Al-Samir (20965502)

    منشور في 2025
    "…In addition, the AQP1 inhibitor 5-(phenoxymethyl)furan-2-carbaldehyde) (5-PMFC) decreases human red cell PO2 by ~40%. All these effects are highly visible at 7/10°C, but minor or absent at 25°C and 37°C, suggesting that O2 passage through the channel(s) increases less with temperature than O2 permeation through membrane lipids. …"
  19. 6319

    SEAwise report on the impact of socioeconomic effects of fisheries management adapted according to input from review workshops حسب Isabella Bitetto (20145735)

    منشور في 2025
    "…For demersal fleets, variable prices caused significant income shifts, though operational effort was independent of price. …"
  20. 6320

    PDLB - Balance Sheet حسب Nguyen Linh (19516642)

    منشور في 2024
    "…</p><p><br></p><p dir="ltr">On the expense side, there was significant concern into the 2023 results about non-interest expense. …"