<b>Epigenetic signatures of treatment with intravenous furosemide plus hypertonic saline solution in decompensated heart failure patients: A Randomized Controlled Trial ( RCT)</b> by Antonino Tuttolomondo (3222708)

“…</p><p dir="ltr">Conclusions: Our findings revealed that in subjects with ADHF , treatment with i.v. furosemide plus HSS significantly decreased the serum levels of IL-6, sST2, hsTnT, galectin-3, and NT-proBNP and modulated some miRNA expression.…”

Data Sheet 1_Global burden of disease for colorectal cancer due to diet low in whole grains from 1990 to 2021 and its projections to 2050: analysis of the global burden of disease... by Mei Yang (51996)

“…Age analysis shows that the disease burden is highest in the 50–85 age group, with males having a significantly higher risk than females. The BAPC model predicts that by 2050, global ASMR and ASDR will further decline, and decomposition analysis shows that population growth is the main reason for the increase in burden.…”

Supplementary file 1_Full-dose versus reduced-dose comparison of direct oral anticoagulants for extended treatment of venous thromboembolism: a systematic review and meta-analysis... by Renshu Zhang (22775495)

“…</p>Conclusion<p>Reduced-dose DOACs were associated with a significant decrease in the risk of major bleeding/CRNMB compared with full-dose DOACs, but were not associated with a significant increase in the risk of recurrent VTE. …”

Data Sheet 1_Empagliflozin’s cardioenergetic protective effects through PPARα pathway modulation in heart failure.pdf by Hua Wei (60877)

“…Post-treatment, MRGlu and glucose uptake decreased markedly in the empagliflozin (EMPG) group, while no significant changes were observed in the fenofibrate (FF) group. …”

Data Sheet 1_The disproportionate burden of pulmonary arterial hypertension among the elderly: global, regional, and national trends from 1990 to 2021—findings from the 2021 global... by Meng Tang (139012)

“…Crucially, the disease burden was significantly higher among females and, notably, the elderly population compared to males and younger age groups. …”

Analyzing the chemical environment of bent bamboo (<i>Phyllostachys iridescens</i>) sections using XRD, XPS, and FTIR analysis by Xuehua Wang (1903936)

“…This indicates that VW undergoes more significant degradation of cellulose and hemicelluloses, while CW experiences a greater loss of extracts. …”

Video 1_The clinical application value of mixed reality in robotic laparoscopic partial nephrectomy.mp4 by Xin Chang Zou (20129301)

“…Within the subgroup with a R.E.N.A.L. score of less than 7 points, the MR group only showed a significant reduction in operation time [(134.55 ± 150.190) min vs. (150.19 ± 28.638) min, P = 0.045], with no notable differences in other parameters. …”

Table 1_The association between oxidative balance scores and all-cause mortality and cancer-specific mortality in cancer survivors: a retrospective cohort study.doc by Ran He (207626)

“…Background<p>Numerous studies have established that oxidative stress significantly affects the long-term survival of cancer survivors. …”

Lactate removal improves overall immune response: by Priyan Bhattacharya (11986545)

“…In highly immune-accessible TMEs, the application of anti-PD1 renders a significant decrease in lactate compared to its pre-ICI counterpart. …”

Data Sheet 1_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.docx by Tao Zhang (43681)

“…Although developed regions had higher incident cases, deaths, and DALYs, they showed more significant declines in ASRs. …”

Table 3_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.xlsx by Tao Zhang (43681)

“…Although developed regions had higher incident cases, deaths, and DALYs, they showed more significant declines in ASRs. …”

Table 2_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.docx by Tao Zhang (43681)

“…Although developed regions had higher incident cases, deaths, and DALYs, they showed more significant declines in ASRs. …”

Table 1_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.docx by Tao Zhang (43681)

“…Although developed regions had higher incident cases, deaths, and DALYs, they showed more significant declines in ASRs. …”

Supplementary Material for: Burden of Neurological disorders in children and adolescents (<20 years old) in North Africa and the Middle East (NAME) from 1990 to 2021 by figshare admin karger (2628495)

“…Abstract Background: Neurological disorders impose a significant health burden globally, particularly in regions like North Africa and the Middle East (NAME) with unique healthcare and societal challenges. …”

Table 1_Oral microbiome components predict response to neoadjuvant chemotherapy in triple-negative breast cancer patients.xlsx by Xiaoyan Fu (5578187)

“…Post-chemotherapy, patients with positive responses demonstrated an increase in Clostridium and Microbacterium species, along with a decrease in Streptococcus and Neisseria. In contrast, no significant changes were observed in the microbiota of patients with poor chemotherapy responses. …”

Image 1_Toward brain-computer interface speller with movement-related cortical potentials as control signals.tiff by José Jesús Hernández-Gloria (20981315)

“…Significant differences in MRCP features were observed between conditions with Laplacian filtering, whereas no significant differences were found in single-site Cz recordings. …”

<i>PSAT1</i> gene as a biomarker for targeting triple negative breast cancer in presence of Rapamycin by Mehdi Roshanian Bakhsh (22469915)

“…The expression of <i>PSAT1</i> in TNBC group was significant higher than normal and other subtypes (<i>p ≤ 0.0001</i>), and was introduced as a biomarker in TNBC that its expression was <i>down-regulated</i> by Rapamycin based on <i>in silico</i> studies. …”

Raw_data_N_adition_increased_SOC_PNAS.xlsx by Guoyong Yan (14273351)

“…We found that SOC significantly increased with N addition, driven by the combined responses of plants, soil, and microbes. …”

Farm labor costs per 0.1 hectares in kg of wheat. by Barak Garty (21696716)

“…Prolonged droughts significantly decrease wine production and extend recovery times beyond a decade. …”

DNMT1 reduces cisplatin sensitivity partially through downregulating FOXO3a in ovarian cancer cells by Chong Guo (5819105)

“…FOXO3a overexpression could significantly enhance cisplatin sensitivity. Meta-analysis also revealed opposite effects on OC patients- prognosis: higher expression of DNMT1 is a risk factor for both overall survival and disease-free survival, while high FOXO3a may improve the 5-year survival rate in high-grade serous adenocarcinoma OC patients. …”