Data_Sheet_1_Role of hypothetical protein PA1-LRP in antibacterial activity of endolysin from a new Pantoea phage PA1.docx حسب Ye Tian (220278)

"…After 24 h of incubation, the OD₆₀₀ value of pET28a-LRP decreased by 0.164 compared to pET28a. Furthermore, the lytic effect of co-expressed PA1-LRP and PA1-Lys was significantly stronger than each separately. …"

<b>Social conditions alter the growth, metabolic rate, behavioral traits, and food-shelter preferences in the qingbo </b><b><i>Spinibarbus sinensis</i></b> حسب Yu-Lin Zhang (9129227)

"…These findings suggest that visual social isolation may not be a significant stressor for qingbo, as the isolation-reared qingbo exhibited improved growth. …"

Forest plot for FEV1/FVC. حسب Xuqin Du (8803772)

"…</p><p>Results</p><p>A total of 16 RCTs involving 1,228 stable COPD patients were included. Compared to standard treatment, QJHTD significantly improved pulmonary function, with increases in FEV1 (MD = 0.32, 95% CI [0.25, 0.38], <i>p </i>= 0.000), FVC (MD = 0.30, 95% CI [0.22, 0.37], <i>p </i>= 0.000), FEV1/FVC (MD = 5.58, 95% CI [4.81, 6.34], <i>p </i>= 0.000), and PaO₂ (MD = 9.62, 95% CI [6.17, 13.08], <i>p </i>= 0.000), and a decrease in PaCO₂ (MD = -9.12, 95% CI [–11.96, –6.28], <i>p </i>= 0.000). …"

Data Sheet 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf حسب Meng Yi (7853249)

"…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …"

Summary of study eligibility criteria. حسب Biban Gill (1473337)

"…<div><p>Background</p><p>A dysbiotic vaginal microbiome (VMB) is associated with clinical conditions such as bacterial vaginosis (BV) and an increased risk of human immunodeficiency virus (HIV-1) infection. Considering the high prevalence of BV among African, Caribbean and Black (ACB) women, we conducted a prospective, randomized, open-label phase 1 clinical trial to determine the feasibility, safety and tolerability of administering low-dose estrogen, probiotics or both in combination to improve vaginal health and decrease HIV-1 susceptibility.…"

Summary of study participation and feasibility. حسب Biban Gill (1473337)

"…<div><p>Background</p><p>A dysbiotic vaginal microbiome (VMB) is associated with clinical conditions such as bacterial vaginosis (BV) and an increased risk of human immunodeficiency virus (HIV-1) infection. Considering the high prevalence of BV among African, Caribbean and Black (ACB) women, we conducted a prospective, randomized, open-label phase 1 clinical trial to determine the feasibility, safety and tolerability of administering low-dose estrogen, probiotics or both in combination to improve vaginal health and decrease HIV-1 susceptibility.…"

Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... حسب Wu Chen (569414)

"…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. Compared to untreated controls, 10-week DBD treatment significantly suppressed lung tumor growth, reduced lesion microvessel density, downregulated HIF-1α and VEGF expression, and ameliorated hematological dysregulation.…"

Table 1_Genetic variants in the vitamin D pathway genes are predictors of the risk of diabetic kidney disease in Central Asian Kazakhstani cohort with type 2 diabetes.docx حسب Binura Taurbekova (21692555)

"…</p>Results<p>The CYP27A1 rs17470271 T/T genotype was significantly associated with a reduced risk of DKD under the recessive model (AOR = 0.32, 95% CI: 0.11–0.93). …"

Single-driver controllability of brain networks. حسب Remy Ben Messaoud (20521877)

"…Values are shown for a representative subject. By decreasing <i>r</i> all values become positive and numerically reliable after a critical threshold <i>r</i>*. …"

Table 1_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx حسب Nianfeng Tang (21536069)

"…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…"

Table 3_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx حسب Nianfeng Tang (21536069)

"…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…"

Table 4_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx حسب Nianfeng Tang (21536069)

"…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…"

Table 2_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx حسب Nianfeng Tang (21536069)

"…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…"

Data Sheet 1_A dual inhibitor of TrxR1 and XIAP induces pyroptosis in melanoma.docx حسب Yuan Wang (14955)

"…In this study, we designed and synthesized a series of derivatives of natural compounds derived from Toona sinensis to simultaneously inhibit TrxR1 activity and destabilize the XIAP protein. The new dual-target inhibitor TRI-03 has significant antiproliferative effects on melanoma cells. …"

Supplemental Tables S1-S5 حسب Kevin Gries (21956942)

"…<p dir="ltr">Regular aerobic exercise decreases the risk of metabolic diseases, however reduced physical activity may attenuate these beneficial adaptations. …"

Table 1_Foxr1 deletion causes microcephaly and leads to cortical and hippocampal hypoplasia.xlsx حسب Hannah Waxman (21429320)

"…Cortical thinning is primarily driven by a significant reduction in layer 2/3 neurons, linked to impaired generation of later-born neurons. …"

Image 1_Foxr1 deletion causes microcephaly and leads to cortical and hippocampal hypoplasia.tif حسب Hannah Waxman (21429320)

"…Cortical thinning is primarily driven by a significant reduction in layer 2/3 neurons, linked to impaired generation of later-born neurons. …"

Charge Delocalization for Electrically Detachable Poly(ionic liquids) Ionoadhesives with Ultrahigh Mechanical Robustness حسب Shijie Sun (9385097)

"…In addition, charge delocalization sharply decreases the escaping energy of mobile ions and thus significantly facilitates ion hopping. …"

Charge Delocalization for Electrically Detachable Poly(ionic liquids) Ionoadhesives with Ultrahigh Mechanical Robustness حسب Shijie Sun (9385097)

"…In addition, charge delocalization sharply decreases the escaping energy of mobile ions and thus significantly facilitates ion hopping. …"

Charge Delocalization for Electrically Detachable Poly(ionic liquids) Ionoadhesives with Ultrahigh Mechanical Robustness حسب Shijie Sun (9385097)

"…In addition, charge delocalization sharply decreases the escaping energy of mobile ions and thus significantly facilitates ion hopping. …"