يعرض 7,101 - 7,120 نتائج من 15,659 نتيجة بحث عن '(( significant decrease decrease ) OR ( significantly i decrease ))~', وقت الاستعلام: 0.70s تنقيح النتائج
  1. 7101

    DataSheet1_Glioma-associated oncogene homolog 1 in breast invasive carcinoma: a comprehensive bioinformatic analysis and experimental validation.docx حسب Teng Qi (278739)

    منشور في 2024
    "…</p>Results<p>The findings reveal dysregulated expression of GLI1 in numerous cancers, with a significant decrease observed in BRCA. …"
  2. 7102

    Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations حسب Han Liu (288039)

    منشور في 2025
    "…Amylomaltases (AMs) can modulate the biochemical properties of α-glucan through a distinctive cyclization feature to form α-1,4-glucoside-linked large-ring polysaccharides (cycloamyloses; CAs), endowing α-glucan with significant health benefits and medical value. …"
  3. 7103

    Image 1_Apolipoprotein C1 -317H1/H2 and the rs4420638 genetic variations and risk of gestational diabetes mellitus in Chinese women: a case-control study.jpeg حسب Wandi Ma (17295430)

    منشور في 2025
    "…However, the combined H1H1/AG+GG genotype was significantly more frequent in women with GDM than in the control group. …"
  4. 7104

    The T-type voltage-gated Ca<sup>2+</sup> channel Ca<sub>V</sub>3.1 involves in the disruption of respiratory epithelial barrier induced by <i>Pasteurella multocida</i> toxin حسب Haixin Bi (6867632)

    منشور في 2025
    "…Knocking out Ca<sub>V</sub>3.1 significantly reduced the cytotoxicity induced by PMT on swine respiratory epithelial cells and mitigated cytoplasmic Ca<sup>2+</sup> inflow stimulated by PMT. …"
  5. 7105

    Data Sheet 1_Pregnancy and contraceptive use among participants of childbearing potential in the HVTN 705 HIV vaccine trial in Southern Africa.docx حسب Pamela Mda (20390050)

    منشور في 2025
    "…Each additional year of age was associated with an 8% decrease in pregnancy incidence (p = 0.014). Women aged 31–35 years had the lowest pregnancy incidence [1.75 (0.48, 4.48) per 100 person-years]. …"
  6. 7106

    Table 2_Improvement of irritable bowel syndrome with glucagon like peptide-1 receptor agonists: a systematic review and meta-analysis.xlsx حسب Mohamed E. A. Mostafa (19834779)

    منشور في 2025
    "…GLP-1 and its analog ROSE-010 have been shown to inhibit the migrating motor complex and decrease gastrointestinal motility in IBS patients.…"
  7. 7107

    Image 2_Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method.jpeg حسب Shiyu Xiao (8147688)

    منشور في 2025
    "…The levels of some TGs in GLs and CEs in STs showed a significant elevation (p < 0.05, VIP > 1). In contrast, most kinds of MGDGs, HexCers, Cers, PEs and FA (18:2) demonstrated a notable decrease in the hippocampus of AD group (p < 0.05, VIP > 1).…"
  8. 7108
  9. 7109

    Table 1_Indole-3-acetic acid enhances ruminal microbiota for aflatoxin B1 removal in vitro fermentation.docx حسب Jiajin Sun (16813628)

    منشور في 2024
    "…AFB1 exposure altered the rumen fermentation pattern, with significantly decreased in the acetic acid/propionic acid ratio (p < 0.05). …"
  10. 7110

    Ybx1 regulation of its target mRNAs is m<sup>5</sup>C-depdendent (Related to Fig 5). حسب Jian Zhang (1682)

    منشور في 2025
    "…<b>(B)</b> RT-qPCR confirmed the expression decreases of Ybx1 target mRNAs in the <i>Ybx1</i> cKO cortices at E13.5, E15.5, and E17.5. …"
  11. 7111

    Effect of TRPML1 on inflammation in lymphedema mice. حسب Lijie Yang (694492)

    منشور في 2024
    "…Compared with that in the WT group, the expression of IL-1β/IL-6/TGF-β1/col-1/vimentin/α-SMA genes was significantly decreased in the TRPML1<sup>−/−</sup> group (*<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001).…"
  12. 7112

    Image 1_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff حسب Ayaka Goto (20858771)

    منشور في 2025
    "…This quantification was also performed in HGFs with suppressed Cav-1 expression using western blotting.</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …"
  13. 7113

    Ydj1 acetylation impacts multiple aspects of translation. حسب Siddhi Omkar (12413434)

    منشور في 2024
    "…<i>ydj1</i>Δ cells expressing plasmids encoding Ydj1 J-domain mutant proteins were transformed with plasmids for the expression of galactose-driven HA-tagged ribosomal proteins. …"
  14. 7114

    Rotarod performance. حسب Gerald Yu Liao (20490394)

    منشور في 2024
    "…</b> C57BL/6J mice at the same age groups also showed statistically significant age-related decrease in performance as seen in CB6F1J mice. …"
  15. 7115

    <b>L-Tryptophan as a Frontier in Diabetes Management: A Pilot Study</b> حسب dr.gayathri M rao (22045067)

    منشور في 2025
    "…A significant increase was seen in pancreatic GLP-1 levels in treatment group. …"
  16. 7116

    Image 1_Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes.tif حسب Yunus E. Dogan (19859574)

    منشور في 2025
    "…Introduction<p>Recombinant alpha-1 antitrypsin (AAT) therapy has been shown to have beneficial effects to mitigate the progression of various diseases. …"
  17. 7117

    Table 1_Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes.docx حسب Yunus E. Dogan (19859574)

    منشور في 2025
    "…Introduction<p>Recombinant alpha-1 antitrypsin (AAT) therapy has been shown to have beneficial effects to mitigate the progression of various diseases. …"
  18. 7118

    Investigating the Impact of Base Pair Mismatches on Cas13d Cleavage Efficiency Using Molecular Dynamics Simulations حسب Ye Liu (296340)

    منشور في 2025
    "…However, the presence of mismatches significantly undermines the cleavage efficiency of Cas13d to target RNA. …"
  19. 7119

    Table 1_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.docx حسب Linjie Peng (12553717)

    منشور في 2025
    "…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …"
  20. 7120