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significantly impact » significant impact (Expand Search), significantly improve (Expand Search), significantly improved (Expand Search)
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2441
Image 1_PLK1 inhibition impairs erythroid differentiation.jpeg
Published 2024“…In this study, we utilized an in vitro human umbilical cord blood-derived CD34<sup>+</sup> cell-based erythroid differentiation system, alongside a murine model, to investigate the impact of PLK1 inhibitors on erythropoiesis. Our results indicate that PLK1 inhibitors, specifically GSK461364 and BI6727, significantly suppress the proliferation of erythroid cells, resulting in G2/M phase cell cycle arrest, increased apoptosis in erythroid cells, and the formation of abnormally nucleated late-stage erythroblasts. …”
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2442
Data Sheet 1_Phyllotaxy and environmental factors influences on leaf trait dimensions in Fraxinus mandshurica: a multidimensional approach within temperate forests.docx
Published 2025“…</p>Results<p>We found that (1) specific leaf area and leaf nitrogen concentration significantly increase along the phyllotaxy gradient (from phyllotaxy 1 to 6), while leaf dry matter content, leaf thickness, and stomatal density significantly decrease. …”
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2443
Supplementary file 1_Influence of circadian rhythm on the determination of the IMMune age indeX (IMMAX).docx
Published 2025“…Introduction<p>To study the impact of immunosenescence on various biological processes the determination of the immune age has gained much interest in recent years. …”
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2444
Table 1_Techno-economic analysis of ocean iron fertilization.docx
Published 2025“…Additionally, the effect of learning rates on determining prospective costs is shown through a sensitivity analysis to have a less significant impact on the overall costs of deployment and, in turn, future cost reductions when large parameter input uncertainties are present. …”
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2445
Image 4_Pediatric kidney transplant recipients are at an increased risk for dysbiosis.jpeg
Published 2025“…</p>Discussion<p>Pediatric KTx recipients demonstrated significant alterarions in gut microbiota composition, indicating dysbiosis. …”
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2446
Image 1_Pediatric kidney transplant recipients are at an increased risk for dysbiosis.jpeg
Published 2025“…</p>Discussion<p>Pediatric KTx recipients demonstrated significant alterarions in gut microbiota composition, indicating dysbiosis. …”
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2447
Image 3_Pediatric kidney transplant recipients are at an increased risk for dysbiosis.jpeg
Published 2025“…</p>Discussion<p>Pediatric KTx recipients demonstrated significant alterarions in gut microbiota composition, indicating dysbiosis. …”
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2448
Image 2_Pediatric kidney transplant recipients are at an increased risk for dysbiosis.jpeg
Published 2025“…</p>Discussion<p>Pediatric KTx recipients demonstrated significant alterarions in gut microbiota composition, indicating dysbiosis. …”
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2449
Supplementary Material for: Phoxilium® as a Phosphate-Sparing Solution for Continuous Renal Replacement Therapy in Paracetamol-Induced Acute Liver Failure
Published 2025“…Phoxilium® patients experienced a small but significant decrease in median arterial pH and standard base excess, which remained within normal limits, but lower than with Accusol® (p = 0.018 and p = 0.046, respectively). …”
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2450
Table 1_TikTok fitspiration and fitness ideal internalisation: gender differences in self-esteem and body satisfaction.docx
Published 2025“…</p>Results<p>Paired-samples t-tests revealed a significant decrease in body satisfaction post-exposure (p < 0.01, Cohen’s d = 0.47), while state self-esteem remained unchanged (p = 0.354, Cohen’s d = 0.023). …”
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2451
Video 1_Nanotopographic control of actin waves and growth cone navigation in developing neurons.avi
Published 2025“…We find that actin-wave speeds do not change significantly in the first 2 weeks of neurite development on flat substrates, but decrease over the same period in neurites on nanoridges. …”
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2452
Data Sheet 1_Nanotopographic control of actin waves and growth cone navigation in developing neurons.pdf
Published 2025“…We find that actin-wave speeds do not change significantly in the first 2 weeks of neurite development on flat substrates, but decrease over the same period in neurites on nanoridges. …”
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2453
Video 2_Nanotopographic control of actin waves and growth cone navigation in developing neurons.avi
Published 2025“…We find that actin-wave speeds do not change significantly in the first 2 weeks of neurite development on flat substrates, but decrease over the same period in neurites on nanoridges. …”
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2454
Table 1_Nanotopographic control of actin waves and growth cone navigation in developing neurons.xlsx
Published 2025“…We find that actin-wave speeds do not change significantly in the first 2 weeks of neurite development on flat substrates, but decrease over the same period in neurites on nanoridges. …”
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2455
Supplementary Material for: Temporal trends of pediatric stroke burden attributable to non-optimal temperature in the United States, 1990-2019: An analysis for the Global Burden of...
Published 2025“…Introduction: Pediatric stroke, though less common than in the elderly population, imposes a significant societal burden. With the increasing impact of climate change, this study aimed to assess the burden of different pediatric stroke subtypes attributable to non-optimal temperatures in the United States and estimate future trends. …”
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2456
Results of Welch’s t-test.
Published 2025“…<div><p>The COVID-19 pandemic triggered social and economic stagnation worldwide, significantly impacting people’s lives. In addition, the Russia-Ukraine war that began in 2022 resulted in rising food prices globally, severely affecting low- and middle-income countries. …”
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2457
PTSD symptom changes during Trauma-Focused Cognitive Behavioural Therapy (TF-CBT) in children and adolescents: a Single-Case Experimental Design study
Published 2025“…A Single-Case Experimental Design (SCED) is used to evaluate the changes and impact of the different modules of TF-CBT.</p> <p><b>Methods:</b> A SCED study with repetitive baseline was conducted. …”
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2458
Data Sheet 1_Antibiotic subclasses differentially perturb the gut microbiota in kidney transplant recipients.pdf
Published 2024“…</p>Results<p>Antibiotic administration was associated with a significant decrease in the Shannon alpha diversity index, a decreased abundance of 11 taxa including Eubacterium and Ruminococcus, and an increased abundance of 16 taxa including Enterococcus and Staphylococcus. …”
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2459
Data Sheet 1_Effects of group sports activities on physical activity and social interaction abilities of children with autism spectrum disorders.docx
Published 2025“…In social interaction ability, the duration of loneliness was significantly reduced (t = −2.567, p < 0.017, Cohen d = 0.57), and the duration of joint participation (t = −3.009, p < 0.007, Cohen d = 0.02) and the regular game (t = −2.511, p < 0.026, Cohen d = 0.46) were significantly increased, respectively. 4 weeks after the intervention, the sedentary behavior and loneliness of the experimental group both continued to decrease. …”
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2460
Data Sheet 1_Emotional prompting amplifies disinformation generation in AI large language models.docx
Published 2025“…Notably, emotional prompting had a significant impact on disinformation production rates, with models showing higher success rates when prompted with polite language compared to neutral or impolite requests. …”