Susceptibility of RUNX1 promoter rs2071029 polymorphism to adjuvant chemotherapy-induced neutropenia in CRC حسب Xikai Luo (21520875)

"…Rs2071029T promoter activity was significantly higher than that of rs2071029C promoter (<i>p</i> = 0.014). …"

Table 2_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

Table 4_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

Table 1_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

Supplementary Material for: Characterisation of an ischaemia-reperfusion model for the formation of a stage II pressure injury in diabetic mice حسب figshare admin karger (2628495)

"…On day 10, db/db mice exhibited delayed wound closure, as well as impaired regeneration of the panniculus carnosus and dermis, with significantly decreased mRNA levels of VEGF and HSP90. …"

<b>Identification and Validation of LOXL2 as a Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma through Multi-Omics and Functional Analysis</b> حسب Ge Qiao (21802511)

"…A Cox proportional hazards model was employed to evaluate the prognostic significance and survival impact of these genes. Functional enrichment and Mendelian randomization analyses were conducted to elucidate the biological pathways and causal roles of lysyl oxidase-like 2 (LOXL2) expression. …"

Supplementary file 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotempor... حسب Ying Feng (151159)

"…Mental disease burden was positively and synergistically associated with PCOS, with the highest impact at BMI P30–60. In contrast, metabolic disease burden was significantly elevated in postmenopausal women, exhibiting a pattern distinct from that of PCOS.…"

Table 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotemporal analysis b... حسب Ying Feng (151159)

"…Mental disease burden was positively and synergistically associated with PCOS, with the highest impact at BMI P30–60. In contrast, metabolic disease burden was significantly elevated in postmenopausal women, exhibiting a pattern distinct from that of PCOS.…"

Data_Sheet_1_Respiratory pathogen analysis in pediatric inpatients unraveled the infection pattern of Mycoplasma pneumoniae post the COVID-19 pandemic.docx حسب Qihong Chen (541270)

"…NPIs reduced MP coinfections and mitigated their severity, while exerting a significant influence on bacterial coinfections with MP over the span of 5 years, in contrast to their impact on viral pathogens.…"

Image 1_NGF/ERK signaling-mediated epigenetic regulation of neuropathic pain in the cerebrospinal fluid-contacting nucleus.tif حسب Guangling Li (6931880)

"…Statistical analysis was performed, with significance set at a p-value of < 0.05.</p>Results<p>CI induced significant upregulation of NGF in the CSF-CN. …"

Table 6_How efficient are specialized public health services in China? A data envelopment analysis and geographically weighted regression approach.docx حسب Qian Bai (605328)

"…Moreover, the geographic variation was a significant issue affecting the sustainable and balanced performance of public health delivery system in China. …"

Table 4_Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential... حسب Daniel Leduc (9191783)

"…Here, we characterize the macrofaunal nematode communities of New Zealand cold seeps for the first time, and at deeper (> 1200 m) seep locations (Maungaroa, Glendhu and Urutī South). There were no significant difference in nematode abundance, species richness, diversity and evenness among the seep areas, which may reflect the lack of difference in most sediment variables. …"

Table 1_The global, regional, and national burden of pediatric stone disease: 1990–2021 and projections for the next two decades.docx حسب Sheng Chen (21971)

"…Background<p>Pediatric stone disease, once considered rare, has gained significant attention over the past decade owing to its rapidly increasing incidence. …"

Table 1_Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential... حسب Daniel Leduc (9191783)

"…Here, we characterize the macrofaunal nematode communities of New Zealand cold seeps for the first time, and at deeper (> 1200 m) seep locations (Maungaroa, Glendhu and Urutī South). There were no significant difference in nematode abundance, species richness, diversity and evenness among the seep areas, which may reflect the lack of difference in most sediment variables. …"

Table 8_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.xlsx حسب Xiaofeng Li (342614)

"…</p>Conclusion<p>We elucidated the significant impact of crotonylation on the ovarian cancer microenvironment and prognosis. …"

Table 9_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.xlsx حسب Xiaofeng Li (342614)

"…</p>Conclusion<p>We elucidated the significant impact of crotonylation on the ovarian cancer microenvironment and prognosis. …"

Table 2_How efficient are specialized public health services in China? A data envelopment analysis and geographically weighted regression approach.docx حسب Qian Bai (605328)

"…Moreover, the geographic variation was a significant issue affecting the sustainable and balanced performance of public health delivery system in China. …"

Table 7_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.csv حسب Xiaofeng Li (342614)

"…</p>Conclusion<p>We elucidated the significant impact of crotonylation on the ovarian cancer microenvironment and prognosis. …"

Table 3_Integrated analysis of single-cell and bulk transcriptomics reveals the prognostic value and underlying mechanisms of crotonylation in ovarian cancer.csv حسب Xiaofeng Li (342614)

"…</p>Conclusion<p>We elucidated the significant impact of crotonylation on the ovarian cancer microenvironment and prognosis. …"