يعرض 4,161 - 4,180 نتائج من 4,412 نتيجة بحث عن '(( significant decrease decrease ) OR ( significantly impact decrease ))~', وقت الاستعلام: 0.37s تنقيح النتائج
  1. 4161
  2. 4162

    Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …"
  3. 4163

    Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …"
  4. 4164

    Data Sheet 1_Lethal and sublethal effects of chemical and bio-insecticides on Spodoptera frugiperda adults: new perspectives for “attract-and-kill” control strategies.pdf حسب Nourhan A. El-Said (22434748)

    منشور في 2025
    "…Sublethal exposure to chlorantraniliprole significantly reduced larval and pupal development durations, decreased pupal weights, and shortened adult longevity in the offspring, without significantly affecting larval mortality, pupation rate, or emergence rate. …"
  5. 4165

    Table_1_Major air pollution and climate policies in NYC and trends in NYC air quality 1998–2021.docx حسب Kathleen Lau (19855266)

    منشور في 2024
    "…In our CCCEH cohorts, between 1998 and 2016, the annual average PM<sub>2.5</sub> and NO<sub>2</sub> concentrations also decreased significantly by 51 and 48%, respectively. …"
  6. 4166

    Data Sheet 1_Preliminary evaluation of a novel serotype O foot-and-mouth disease mRNA vaccine.docx حسب Jingang Zhao (20416198)

    منشور في 2025
    "…<p>Foot-and-mouth disease virus (FMDV) is one of the most significant animal pathogens worldwide, severely impacting the health and productivity of pigs, cattle, sheep, and other ungulates. …"
  7. 4167

    Data Sheet 2_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.docx حسب Wenjun Li (41954)

    منشور في 2025
    "…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …"
  8. 4168

    Data Sheet 1_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.pdf حسب Wenjun Li (41954)

    منشور في 2025
    "…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …"
  9. 4169

    Table1_The association of physical activity with kidney function risk among adults with long working hours.docx حسب Tenglong Yan (14132220)

    منشور في 2024
    "…However, whether PA can offset the negative impact of long working hours on kidney function was unclear, which is the focus of this study.…"
  10. 4170

    Data Sheet 5_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

    منشور في 2025
    "…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"
  11. 4171

    Data Sheet 9_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

    منشور في 2025
    "…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"
  12. 4172

    Data Sheet 6_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

    منشور في 2025
    "…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"
  13. 4173

    Data Sheet 10_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

    منشور في 2025
    "…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"
  14. 4174

    Data Sheet 8_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

    منشور في 2025
    "…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"
  15. 4175

    Data Sheet 1_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

    منشور في 2025
    "…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"
  16. 4176

    Data Sheet 11_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

    منشور في 2025
    "…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"
  17. 4177

    Supplementary file 1_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.xlsx حسب Erdengqieqieke Ye (19542808)

    منشور في 2025
    "…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"
  18. 4178

    Data Sheet 4_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

    منشور في 2025
    "…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"
  19. 4179

    Data Sheet 7_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

    منشور في 2025
    "…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"
  20. 4180

    Data Sheet 3_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

    منشور في 2025
    "…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"