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significantly impacts » significantly impact (Expand Search), significant impact (Expand Search), significantly improves (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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3241
Dupilumab improves sense of smell and clinical outcomes in patients with severe chronic rhinosinusitis with nasal polyps with anosmia
Published 2024“…<p>Loss of sense of smell is a cardinal symptom of chronic rhinosinusitis with nasal polyps (CRSwNP) and significantly impacts health-related quality-of-life. …”
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3242
Data Sheet 1_Beat-to-beat coronary wave intensity analysis: implications of backward waves originating from microvascular.docx
Published 2025“…Neither functional stenotic lesions nor vessel type [left anterior descending coronary artery (LAD) or right coronary artery (RCA)] significantly impacted quantitative parameters of the microvascular-originated backward waves.…”
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3243
Image 1_Innate immune pathway activation to modulate mesenchymal stromal cell (MSC) interactions with synovium and cartilage.jpeg
Published 2025“…STING-MSC-CM vs TLR-MSC-CM induced 38 significantly altered DEGs in synoviocytes, 20 in chondrocytes, and 47 in macrophages.…”
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3244
Data Sheet 1_Effects of irrigation and fertilization management on kiwifruit yield, water use efficiency and quality in China: A meta-analysis.zip
Published 2025“…The results showed that the response of kiwifruit to water management was particularly significant in areas with annual average rainfall > 800 mm and field water holding capacity > 28%, and excessive irrigation had a greater negative impact on yield and WUE. …”
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3245
Data Sheet 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.xlsx
Published 2025“…On the contrary, a chaotic home environment is associated with decreased well-being. We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …”
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3246
Table 1_Effects of irrigation and fertilization management on kiwifruit yield, water use efficiency and quality in China: A meta-analysis.xls
Published 2025“…The results showed that the response of kiwifruit to water management was particularly significant in areas with annual average rainfall > 800 mm and field water holding capacity > 28%, and excessive irrigation had a greater negative impact on yield and WUE. …”
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3247
Data Sheet 2_Improved early postoperative cognition in elderly gastrointestinal patients: a randomized controlled trial on the role of ultrasound-guided stellate ganglion block.doc
Published 2025“…The hemodynamic indicators showed a slight reduction in intraoperative blood pressure and decreased numerical rating scale scores on the first postoperative day without significant differences in other indicators.…”
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3248
Data Sheet 1_Improved early postoperative cognition in elderly gastrointestinal patients: a randomized controlled trial on the role of ultrasound-guided stellate ganglion block.doc...
Published 2025“…The hemodynamic indicators showed a slight reduction in intraoperative blood pressure and decreased numerical rating scale scores on the first postoperative day without significant differences in other indicators.…”
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3249
Data Sheet 1_Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis.zip
Published 2025“…These findings suggest that Leishmania infection may regulate PC remodeling in the host liver and increase membrane phospholipid metabolism, resulting in the production of a series of lipid mediators that participate in immune regulation; this could have a significant impact on the survival of Leishmania in the host and on the progression of the disease.…”
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3250
Supplementary file 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.docx
Published 2025“…On the contrary, a chaotic home environment is associated with decreased well-being. We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …”
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3251
Global divergent responses of soil heterotrophic respiration to nitrogen deposition
Published 2025“…Δ<i>R</i><sub>H</sub> significantly increased in alkaline soils (pH > 7.5) but decreased in acidic soils (pH < 5.5). …”
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3252
Toxic effects of tetracycline on non-target lichen <i>Evernia prunastri</i>
Published 2024“…At higher TC concentrations, 500 mg/L SOD activity was significantly elevated. In the case of CAT, APX and GR, TC at higher concentrations significantly decreased these enzymic activities. …”
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3253
Supplementary Material for: The effectiveness of regionalization of perinatal care and specific facility-based interventions: A systematic review
Published 2024“…Results: Implementation of regionalization programs significantly decreased maternal and perinatal mortality. …”
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3254
Numerical Study of the Mechanical Properties and Failure Mechanisms of Shale Under Different Loading Conditions
Published 2025“…The results reveal the following key findings: (1) With an increase in the bedding angle, the uniaxial compressive strength of shale shows a U-shaped change trend, while the tensile strength gradually decreases. Under the two loading conditions, the failure mechanism of the samples is significantly different, and the influence of the bedding distribution position on the direct tensile failure mode is more significant. (2) The confining pressure reduces the brittleness and anisotropy of shale by altering the internal stress distribution and inhibiting the propagation of microcracks. …”
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3255
Data Sheet 6_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip
Published 2025“…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
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3256
Data Sheet 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.docx
Published 2025“…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
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3257
Data Sheet 7_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip
Published 2025“…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
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3258
Data Sheet 3_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip
Published 2025“…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
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3259
Table 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.xlsx
Published 2025“…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
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3260
Data Sheet 2_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip
Published 2025“…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”