DataSheet1_Coptisine enhances the sensitivity of chemoresistant breast cancer cells by inhibiting the function and expression of ABC transporters.PDF by Safaa Yehia Eid (17768736)

“…In MCF-7/ADR and MDA-MB-231/ADR cells, COP (31 μM) enhanced DOX cytotoxicity with CI (0.77 and 0.75), RR (2.58 and 3.33), and IB suggesting synergism. COP significantly inhibits ABCT function in resistant BC cell lines, increases Rho123 accumulation, and decreases efflux more than VER; 2.1 and 1.2-fold, respectively. …”

Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts by Yu-Tse Lee (19944891)

“…The synergistic effect of MSN-PEG/TA 25 combined with liposomal-encapsulated doxorubicin (Lipo-Dox) significantly boosted mouse survival rates, outperforming Lipo-Dox monotherapy. …”

Image 3_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff by José De Jesus Bravo-Silva (21898316)

“…</p>Results<p>Melatonin treatment significantly reduced ZIKV and DENV-4 replication and the associated inflammatory response in U87-MG cells. …”

Image 2_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff by José De Jesus Bravo-Silva (21898316)

“…</p>Results<p>Melatonin treatment significantly reduced ZIKV and DENV-4 replication and the associated inflammatory response in U87-MG cells. …”

Image 1_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a... by Linxi Qian (555385)

“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”

Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts by Yu-Tse Lee (19944891)

“…The synergistic effect of MSN-PEG/TA 25 combined with liposomal-encapsulated doxorubicin (Lipo-Dox) significantly boosted mouse survival rates, outperforming Lipo-Dox monotherapy. …”

Data Sheet 2_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip by JunBao Yu (22442218)

“…</p>Results<p>AFE treatment significantly alleviated the severity of colitis, as evidenced by reduced DAI scores, attenuated colon shortening, and improved histopathological damage. …”

Data Sheet 1_Differential concentrations of NaCl and K2Cr2O7 stress conditions: biophoton characteristics and quality prediction feasibility analysis of fresh Nepeta cataria L. lea... by Ruyu Wang (12611791)

“…</p>Results<p>Stress conditions significantly inhibited NcL growth and quality, leading to marked differences in biophoton emission, physiological and biochemical indicators, oxidative stress indexes and PG content between stress and control groups. …”

Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts by Yu-Tse Lee (19944891)

“…The synergistic effect of MSN-PEG/TA 25 combined with liposomal-encapsulated doxorubicin (Lipo-Dox) significantly boosted mouse survival rates, outperforming Lipo-Dox monotherapy. …”

Supplementary file 1_ZnO nanoparticles induce acute arrhythmia and heart failure in mice by disturbing cardiac ion channels.pdf by Xuexue Liu (3271641)

“…Mechanistically, exposure to ZnO NPs did not significantly affect the IK1, but it markedly decreased I_Na and I_Ca−L currents, resulting in a reduced amplitude and shortened duration of the action potential in cardiomyocytes. …”

Data Sheet 1_Personalized temporal interference stimulation targeting striatum reduces functional stability and dynamic connectivity variability in the sensorimotor network.docx by Dongsheng Tang (5526149)

“…</p>Results<p>(1) Functional stability: TI stimulation significantly decreased functional stability in bilateral SMA regions (predominantly SMA proper, with parts of pre-SMA) compared to Sham and baseline conditions (P < 0.01). (2) Dynamic functional connectivity: TI stimulation reduced dFC variability between the right striatum and left SMA region (predominantly SMA proper, with parts of pre-SMA) compared to baseline (P < 0.01). (3) Safety: No adverse cognitive effects or side effects were observed, with good blinding effectiveness maintained throughout the study.…”

Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i> in an organotypic 3D lung epithelial cell model by Merel Wauters (21333023)

“…Compared to the <i>lasB</i> mutant, the wild-type strain significantly decreased inflammation by degrading MCP-1, IL-1β, GM-CSF, and IL-8. …”

DataSheet1_Integration of smart charging of large-scale electric vehicles into generation and storage expansion planning: a case study in south china.pdf by Lei You (542435)

“…The numerical results show that the implementation of smart charging can significantly alter the decisions of GSEP. As the participation rate of smart charging improves from 0% to 90%, there is an additional 1,800 MW installation in wind and solar power, while the need to build new batteries is noticeably reduced; also, depending on the level of EV uptake, the annualized total system cost decreases by 5.11%–7.57%, and the curtailment of wind and solar power is reduced by 10.34%–19.64%. …”

What is the optimal In2Care stations density to achieve Aedes aegypti population reduction in a dengue endemic setting? by Rafael Freitas (16738416)

“…</p><p dir="ltr"><b>Conclusions/Significance:</b> The density of In2Care stations varied across neighborhoods, ranging from 220 to 555 stations per km². …”

Granite sample. by Run-Zhi Jia (21262716)

“…Prior to reaching peak strength, energy accumulation predominated, shifting to dissipation and release after the peak was surpassed. Notably, the impact of confining pressure on fthe elastic deformation energy of the rock mass was more significant than on dissipative deformation energy.…”

X-ray diffractometer and mineral composition. by Run-Zhi Jia (21262716)

“…Prior to reaching peak strength, energy accumulation predominated, shifting to dissipation and release after the peak was surpassed. Notably, the impact of confining pressure on fthe elastic deformation energy of the rock mass was more significant than on dissipative deformation energy.…”

The sample in 2015, 2018, and 2021. by Wenqi Li (137889)

“…<div><p>Exploring the spatial structure of residential land prices within metropolitan areas is crucial for identifying regional development disparities. It holds significant practical value for guiding the rational allocation of resources, optimizing land use efficiency, and promoting collaborative development across the metropolitan region. …”

Continuous-discontinuous coupling model. by Run-Zhi Jia (21262716)

“…Prior to reaching peak strength, energy accumulation predominated, shifting to dissipation and release after the peak was surpassed. Notably, the impact of confining pressure on fthe elastic deformation energy of the rock mass was more significant than on dissipative deformation energy.…”

Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study by Dong Dong (23216)

“…<p>Endoscopic nasopharyngectomy represents a significant intervention for recurrent nasopharyngeal carcinoma (NPC). …”

Enhanced Anthropogenic Contributions to Marine Aerosols and trace elements Compared to Coastal Regions in Northern China by Yang Zhou (17600586)

“…These results highlight significant interaction between sea salt and dust or anthropogenic elements, which may enhance the solubility of these trace elements. …”