Video 4_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Data Sheet 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Data Sheet 2_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx by Xinxin Wang (134010)

“…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …”

Data Sheet 1_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx by Xinxin Wang (134010)

“…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …”

Table 1_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx by Xinxin Wang (134010)

“…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …”

Data Sheet 3_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx by Xinxin Wang (134010)

“…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …”

Supplementary file 1_Associations between the METS-IR index and cognitive function in community-dwelling Chinese middle-aged and older adult individuals: a cross-sectional study.do... by Nian Jiang (1338381)

“…In addition, there was a specific nonlinear relationship between the METS-IR index and cognitive impairment (the inflection point was 38.1). Lowering the METS-IR index below 38.1 through lifestyle changes and diet control can significantly reduce the risk of cognitive impairment and may decrease the incidence of dementia.…”

Supplementary file 2_Associations between the METS-IR index and cognitive function in community-dwelling Chinese middle-aged and older adult individuals: a cross-sectional study.do... by Nian Jiang (1338381)

“…In addition, there was a specific nonlinear relationship between the METS-IR index and cognitive impairment (the inflection point was 38.1). Lowering the METS-IR index below 38.1 through lifestyle changes and diet control can significantly reduce the risk of cognitive impairment and may decrease the incidence of dementia.…”

Data Sheet 1_The mediating role of body surface area-adjusted basal metabolic rate: effects of low muscle mass and central obesity on cognitive impairment in Chinese patients with... by Ya-Jie Zhai (20609765)

“…Central obesity, low muscle mass, and low energy expenditure significantly elevate CI risk in this population.</p>…”

Dendritic spine density in both apical and basal porcine cortical pyramidal cells 1 hour after impact. by Brendan Hoffe (20775702)

Table 2_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.docx by Ilmari Pyykkö (2855153)

“…QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…”

Data Sheet 3_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.pdf by Ilmari Pyykkö (2855153)

“…QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…”

Table 1_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.docx by Ilmari Pyykkö (2855153)

“…QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…”

Data Sheet 2_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.pdf by Ilmari Pyykkö (2855153)

“…QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…”

Image 6_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif by Ilmari Pyykkö (2855153)

“…QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…”

Image 4_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif by Ilmari Pyykkö (2855153)

“…QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…”

Image 5_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif by Ilmari Pyykkö (2855153)

“…QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…”

Image 1_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif by Ilmari Pyykkö (2855153)

“…QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…”